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https://www.mrc-mbu.cam.ac.uk/files/impi-2020-q3pre.xlsx1 Oct 2021: Table Legend. Supplementary Data: IMPI. Data sets for protein-encoding human genes in Ensembl. Annotation includes: Evidence of subcellular localisation; Manual curation of literature; IMPI localisation score for likelihood of a mitochondrial -
School of Clinical Medicine Cambridge Institute for Medical Research…
https://www.cimr.cam.ac.uk/files/cimr_anniversary_research_report_2018_web.pdf23 Jun 2021: retrovirus silencing. 18 A key quality control step in ribosome assembly. ... We discovered the ‘Human Silencing Hub’ (HUSH), an epigenetic transcriptional repressor complex which silences newly integrated retroviruses such as HIV, as well as -
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https://www.mrc-mbu.cam.ac.uk/files/impi-2021-q4pre-20211001-dist_0.xlsx4 Oct 2021: Legend. Integrated Mitochondrial Protein Index (IMPI) [2021Q4pre-20211001]. Sheets:. 1) Table Legend. 2) IMPI All Human Genes (Ensembl): All human genes with annotation, curation and IMPI localisation score. Ensembl Gene ID: Gene identifier for Results that match 1 of 2 words
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Cryptochrome proteins are integral to maintain time within the…
https://www2.mrc-lmb.cam.ac.uk/cryptochrome-proteins-are-integral-to-maintain-time-within-the-brains-master-clock/20 Jan 2022: Published on. 20 January, 2022. A schematic showing the effect of CRY1 on the relationships between localisation and intracellular mobility of endogenous fluorescently tagged PER2 as well as circadian rhythmicity of ... Real-time imaging of endogenous -
Nine Cambridge scientists among the new 2022 Fellows announced by the …
https://www.cam.ac.uk/research/news/nine-cambridge-scientists-among-the-new-2022-fellows-announced-by-the-royal-society10 May 2022: His discovery of the ‘HUSH’ epigenetic silencing complex explains how the genome distinguishes new genetic material from endogenous genes through recognition of intronless DNA. -
2022 John Kendrew Lecture to be given by Alice Ting - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/2022-john-kendrew-lecture-to-be-given-by-alice-ting/5 May 2022: Enzyme-catalyzed proximity labeling (PL) has emerged as a powerful and generalizable method to map the locations and interactions of endogenous proteins in the context of living cells, applicable to even -
Functional human replisome reconstituted for the first time - MRC…
https://www2.mrc-lmb.cam.ac.uk/functional-human-replisome-reconstituted-for-the-first-time/18 May 2022: Replisomes facing exogenous and endogenous stress, or replisome components that have become mutated, have also been identified as a characteristic of cancerous cells. -
Cambridge University Reporter Special
https://www.reporter.admin.cam.ac.uk/reporter/2008-09/weekly/6157/25.html28 Jan 2022: therapies. In addition a better understanding of the molecular mechanisms regulating stem cell behaviour will lead to the development of small molecules that can influence the differentiation of endogenous stem cells. -
Fluid Mechanics of Mosaic Ciliated Tissues
www.damtp.cam.ac.uk/user/lauga/papers/204.pdf29 Nov 2021: While the flowdriven by a single such vortex decays quickly with distancefrom the skin, we show that long range contributions ofother bundles slows the decay of this endogenous flow anddetermines the ... Lateralvelocity at (e) x; y ð0; 0Þ and (f) ð40 -
Fluid Mechanics of Mosaic Ciliated Tissues
www.damtp.cam.ac.uk/user/gold/pdfs/mosaic.pdf2 Nov 2021: While the flowdriven by a single such vortex decays quickly with distancefrom the skin, we show that long range contributions ofother bundles slows the decay of this endogenous flow anddetermines the ... Lateralvelocity at (e) x; y ð0; 0Þ and (f) ð40
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