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Poster Abstracts | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/poster-abstracts23 Feb 2024: Background: The apelin receptor, a class A GPCR, binds two endogenous peptide ligands, apelin and ELA, to induce potent vasodilatation and increase cardiac output. ... Considering these limitations, we are developing a novel method for stimulating -
vsvg_pseudtyped_retrovirus_101209_0clip_image004.png | Ron Lab
https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage004png23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image004.png. 2024 University of Cambridge. -
Dr Wei Li | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wli23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Research
https://www.med.cam.ac.uk/li/research/23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Dr Janet Maguire | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/jmaguire23 Feb 2024: Pyr. 1. ]apelin-13. (1-12). is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr. ... Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration -
Robyn Macrae | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/robyn-macrae23 Feb 2024: Title: The apelin signalling system is composed of the G-protein coupled apelin receptor and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). ... Structure and pharmacology of the apelin receptor with a recommendation that -
Dr Andrew Sage | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/asage23 Feb 2024: Recently, our lab defined the direct overall contribution of endogenous antibodies to atherosclerosis in a fully immunocompetent model. -
Professor Robert Glen | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/rglen23 Feb 2024: FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes. -
Professor Guy Brown | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/gbrown23 Feb 2024: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease. -
Professor Colin Taylor | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/ctaylor23 Feb 2024: Endogenous signalling pathways and caged-IP. 3. evoke Ca. 2+. puffs at the same abundant immobile intracellular sites.
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