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Opinion: Want to eradicate viruses? They made us who we are |…
https://www.cam.ac.uk/research/discussion/opinion-want-to-eradicate-viruses-they-made-us-who-we-are28 Feb 2017: While HIV infects immune cells, when a retrovirus instead infects the cells that produce eggs or sperm, the viral DNA can be inherited by any offspring. ... All these viruses which inserted into our DNA long ago are termed endogenous retroviruses (ERVs). Results that match 1 of 2 words
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The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress…
www-vendruscolo.ch.cam.ac.uk/aprile2017sr.pdf17 Sep 2017: Cas9 system21 for disruption of endogenous expression of the DNAJB6 gene in HEK293T cells. ... B) Immunocytochemistry showing expression of the endogenous DNAJB6a and DNAJB6b forms in α-syn-DsRed HEK293T cells. -
PowerPoint Presentation
https://www.ch.cam.ac.uk/files/posters/Duer2.pdf28 Aug 2017: Possible assignments are given below. This suggeststhat there are endogenous precursors of glycating sugars such aspoly-(ADP-ribose) which can be converted to glycating sugars,ribose-5-phosphate and ribose. -
Folate and formaldehyde: from vitamin to genotoxin to DNA building…
https://www2.mrc-lmb.cam.ac.uk/folate-and-formaldehyde-from-vitamin-to-genotoxin-to-dna-building-block/17 Aug 2017: They further showed that when the protection against this molecule is removed in mice then the levels of endogenous formaldehyde rise leading to overwhelming DNA damage and rapid death. -
Science issue: On the road to beating HIV / AIDS | Murray Edwards…
https://www.murrayedwards.cam.ac.uk/news/our-blogs/she-talks-science/science-issue-on-the-road-to-beating-hiv-aids28 Sep 2017: Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)”. -
REPORT◥ PROTEOSTASIS UBE2O is a quality control factor fororphans ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017b.pdf4 Aug 2017: Catalytically inactive UBE2O(C1040S) alsorecovered endogenous and exogenous RPL24(but no detectable ubiquitinated forms), whereasUBE2O(DCR2) interacted poorly with RPL24 (fig.S10D). ... The heterogeneity of ubiquitin bands in the samples with cytosol is -
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www.damtp.cam.ac.uk/user/gold/pdfs/dynactin.pdf16 Oct 2017: phenotype. (D–E) Confocal images of fluorescent in situ hybridisations (FISH) to endogenous oskar mRNA in a. -
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence …
www.jiggins.gen.cam.ac.uk/pdfs/lewis2017.pdf5 Dec 2017: Virus identification and genome assembly. To identify viruses, we first mapped RNA-Seq reads to the genome of the host species to exclude genome-derived transcripts, thus filtering out endogenous viral ... Nat. Commun. 7, 13856 (2016). 9. Ghildiyal, M. -
Common class of chemicals increase cancer risk by breaking down DNA…
https://www.cam.ac.uk/research/news/common-class-of-chemicals-increase-cancer-risk-by-breaking-down-dna-repair-mechanisms1 Jun 2017: A class of environmental and endogenous toxins induces BRCA2 haploinsufficiency and genome instability. -
REPORT◥ PROTEIN HOMEOSTASIS Mechanistic basis for a moleculartriage…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017.pdf19 Jan 2017: endogenous proteins with recombinant variantsrevealed the functional roles for all of the factorsand interactions. ... C) Immunoblots (IB) for triage components of control or BAG6 complex-depleted RRL replenished with recombinant BAG6 sub-complexes used
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