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AOC minutes 17th November 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_171123_redacted.pdf14 May 2024: Commonalities: 1 Microchip, 1 hind limb paralysis, 16 compound-related (cell solution, MIA toxicity, high IGA), 10 mice found dead, 9 weight loss, 2 irradiation, 2 Leukaemia, 2 G/A IVIS, -
Regulation of the mammalian reproductive axis
https://www.ubs.admin.cam.ac.uk/system/files/public/regulation_of_the_mammalian_reproductive_axis._non-technical_summary_redacted.pdf30 Apr 2024: Some mice will have small microchips implanted subcutaneously to allow future identification or for monitoring temperature. ... Subcutaneous implantation of microchips will be carried out under sterile conditions and are not expected to have any -
Discovery and development of treatments for immunological diseases
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf29 Apr 2024: In a typical simple immune challenge experiment, adult mice would be implanted with identification microchips under anaesthetic and a few days later weighed and dosed (the dose given being related to -
PK and PKPD studies to support Respiratory and Immunology research
https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf30 Apr 2024: In a typical pharmacokinetic experiment, adult mice would be implanted with identification microchips under anaesthetic and a few days later weighed and dosed (the dose given being related to the weight
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