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https://www.pdn.cam.ac.uk/taxonomy/term/59/feed
https://www.pdn.cam.ac.uk/taxonomy/term/59/feed10 Jul 2024: Department of Physiology, Development and Neuroscience - Academics https://www.pdn.cam.ac.uk/directory/faculty en Sumru Bayin https://www.pdn.cam.ac.uk/staff/bayin <div class="field field-name-field-sd-consultancy field-type-list-boolean -
Publications - Kaser Group
https://www.med.cam.ac.uk/kaser/publications/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Kaser Group. Publications. Reviews & Editorials. 2024 University of Cambridge. -
Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/directory/brian-huntly23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead -
Dr Pentao Liu | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some -
Professor Margaret Ashcroft | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell -
Publications - Professor Marciniak's Group
https://www.med.cam.ac.uk/marciniak/publications/23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress. -
Computational modelling of cancer and aging | Department of Genetics
https://www.gen.cam.ac.uk/research/research-groups/computational-modelling-cancer-and-aging10 Jul 2024: Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia. -
Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…
https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast9 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and -
https://www.pdn.cam.ac.uk/taxonomy/term/58/feed
https://www.pdn.cam.ac.uk/taxonomy/term/58/feed10 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis. -
Dr Maria Christophorou | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/christophorou23 Feb 2024: She did her PhD with Gerard Evan at UCSF, where she was able to dissect the relative contributions of different p53 activating signals towards tumour suppression using mouse models of conditional ... p53 perturbation.
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