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Dr Vaithish Velazhahan | Gonville & Caius
https://www.cai.cam.ac.uk/people/dr-vaithish-velazhahan5 Jul 2024: and Schrick, K., 2020. Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53. -
Dr Mattia Frontini | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/mfrontini23 Feb 2024: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. ... CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination. -
Graduate Poster Display | Pembroke
https://www.pem.cam.ac.uk/college/news/graduate-poster-display6 Jul 2024: Chiba Ene (PhD Medical Sciences) - Histone demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Activity through Lysine Demethylation. -
Publications | Centre for Experimental Biophysical Chemistry
https://www.ch.cam.ac.uk/biophyschem/publications?authors_op=word&page=59 Jul 2024: Nat Neurosci. (2022). 25,. 1582. (doi: 10.1038/s41593-022-01206-2). Characterization of full-length p53 aggregates and their kinetics of formation. -
Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/pi/huntly23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead -
Research - Professor Marciniak's Group
https://www.med.cam.ac.uk/marciniak/research/23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress. -
Publications | Knowles Lab
https://www-knowles.ch.cam.ac.uk/publications9 Jul 2024: Journal: Scientific Reports 12 (1). ------------------------------. Characterization of full-length p53 aggregates and their kinetics of formation. -
Protein engineering pioneer awarded Royal Society Copley Medal |…
https://www.ch.cam.ac.uk/news/protein-engineering-pioneer-awarded-royal-society-copley-medal9 Jul 2024: His work is now focussed on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53 – the so-called “Guardian of the Genome” – in order to design novel -
Ingo Ringshausen | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/directory/ingo-ringshausen23 Feb 2024: Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Cancer Cell, 2006. 10(6): p. 501-14 PMID:17157790. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI The pathological response to DNA damage does not -
Search Publications | Publications
https://publications.ch.cam.ac.uk/publications-search?page=7969 Jul 2024: Structural biology of the tumor suppressor p53.
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