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23 Feb 2024: Published in The Lancet Oncology, researchers evaluated the role of the Cytosponge atypia, p53 overexpression, and clinical risk factors (age, sex, and segment length) to prioritise patients for endoscopy.

23 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-02-06T11:14:05","modified_gmt":"2015-02-06T11:14:05","slug":"publications","status"

23 Feb 2024: 2018) Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.

23 Feb 2024: Swigart, and G.I. Evan. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Finch, L.B. Swigart, and G.I. Evan. Thepathological response to DNA damage does not contribute to p53-mediated tumour suppression.

29 Jan 2024: Chin, W. Fischle, S.M. Gasser. EMBO J. 2011. 30: 2610-2621. (53) Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.

27 Jul 2024: Department of Pharmacology - Academic Staff https://www.phar.cam.ac.uk/directory/academicstaff An A-Z directory of all Department members can be found here. The Department provides contact details for all members of the Department. Please follow the

27 Jul 2024: Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia.

23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some

26 Jul 2024: He hates collars, takes no milk in his tea through fear of dead flies, and is a confirmed Peripatetic after bump-suppers” (Chanticlere, Lent Term 1909, p53 and p37 respectively).