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21 - 30 of 114 search results for p53

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  2. Dr Vaithish Velazhahan | Gonville & Caius

    https://www.cai.cam.ac.uk/people/dr-vaithish-velazhahan
    24 Jul 2024: and Schrick, K., 2020. Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53.

  3. Featured Articles Archives - Page 14 of 32 - School of Clinical…

    https://www.medschl.cam.ac.uk/category/feature/page/14/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  4. Graduate Poster Display | Pembroke

    https://www.pem.cam.ac.uk/college/news/graduate-poster-display
    24 Jul 2024: Chiba Ene (PhD Medical Sciences) - Histone demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Activity through Lysine Demethylation.

  5. Dr Mattia Frontini | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/mfrontini
    23 Feb 2024: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. ... CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.

  6. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/pi/huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  7. spongistatin 1

    https://www-jmg.ch.cam.ac.uk/data/molecules/polyketides/spongistatin.html
    18 Jul 2024: s66;P5;P57;P53;P52;P50;P24;N8;s3;s76;d76;N15;s79;N17;N29;N24;s82;s84;d84;/rC:-.3572,3.7125,0;-.3572,2.8875,0;1.0717,2.

  8. Research - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/research/
    23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

  9. Publications | Knowles Lab

    https://www-knowles.ch.cam.ac.uk/publications
    24 Jul 2024: Journal: Scientific Reports 12 (1). ------------------------------. Characterization of full-length p53 aggregates and their kinetics of formation.

  10. Ingo Ringshausen | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/ingo-ringshausen
    23 Feb 2024: Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Cancer Cell, 2006. 10(6): p. 501-14 PMID:17157790. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI The pathological response to DNA damage does not

  11. Protein engineering pioneer awarded Royal Society Copley Medal |…

    https://www.ch.cam.ac.uk/news/protein-engineering-pioneer-awarded-royal-society-copley-medal
    24 Jul 2024: His work is now focussed on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53 – the so-called “Guardian of the Genome” – in order to design novel

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