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AOC Minutes 18th August 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_180823_redacted.pdf23 Jan 2024: There were 36 SC18’s this month Commonalities included nose bleeds, microchips, tumours exceeding limits. -
AOC Minutes 22nd September 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_220923_redacted.pdf14 May 2024: Minutes. four compound related. Five different lumps other than tumours, six microchip incidents, two seizures and two hind limb paralysis. -
AOC minutes 17th November 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_171123_redacted.pdf14 May 2024: Commonalities: 1 Microchip, 1 hind limb paralysis, 16 compound-related (cell solution, MIA toxicity, high IGA), 10 mice found dead, 9 weight loss, 2 irradiation, 2 Leukaemia, 2 G/A IVIS, -
AOC Minutes 21st April 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_210423_redacted.pdf17 Jan 2024: Other commonalities are microchip bruising and haemorrhage, nose bleeds, Tamoxifen animals, and metastatic tumour. -
AOC Minutes 17th February 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_170223_redacted.pdf17 Jan 2024: reported that there have been 31 Standard Condition 18’s since the last meeting with repeat issues regarding Weight loss; Microchip bruising/haemorrhage; i/p injection; o/g technique; miss-dose; -
AOC Minutes 19th May 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_190523_redacted.pdf17 Jan 2024: health issues, 5 mice ‘found dead’, 1 trembling, 6 Microchip bruising/haemorrhage/wounds, 4 Tamoxifen (2 OG, 2 i/p), 1 eye concern, 5 tumours, 1 post-surgical procedure, 1 weight -
Regulation of the mammalian reproductive axis
https://www.ubs.admin.cam.ac.uk/system/files/public/regulation_of_the_mammalian_reproductive_axis._non-technical_summary_redacted.pdf30 Apr 2024: Some mice will have small microchips implanted subcutaneously to allow future identification or for monitoring temperature. ... Subcutaneous implantation of microchips will be carried out under sterile conditions and are not expected to have any -
Discovery and development of treatments for immunological diseases
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf29 Apr 2024: In a typical simple immune challenge experiment, adult mice would be implanted with identification microchips under anaesthetic and a few days later weighed and dosed (the dose given being related to -
PK and PKPD studies to support Respiratory and Immunology research
https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf30 Apr 2024: In a typical pharmacokinetic experiment, adult mice would be implanted with identification microchips under anaesthetic and a few days later weighed and dosed (the dose given being related to the weight
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