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LMB Fellows - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/lmb-fellows/23 Apr 2024: His application of forward-genetic screens discovered the Human Silencing Hub ‘HUSH’, the critical transcriptional epigenetic repressor complex for silencing both newly integrated retroviruses and mobile endogenous retrotransposons. -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: This yielded protein levels of CreS similar to endogenous levels in wt strain CB15N (SI Appendix, Fig. ... Subcellular Organization of CreS Filaments. The ultrastructure of endogenous CreS assemblies at normal levels in C. -
Mouse developmental genetics to study neurodevelopment and disease…
https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf30 Apr 2024: Importantly, in the long term, this project will provide a springboard to utilize endogenous neural stem cells as therapeutic entry points for regenerative medicine in the brain.
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