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Understanding Infection Pathogenesis to Guide Therapies…
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf30 Apr 2024: Mice that are immunised can show mild signs of discomfort that should last no more than 24 hours. -
Neurobehavioural Mechanisms Underlying Mood, Anxiety and…
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf30 Apr 2024: We have published these findings in animal welfare journals. However, 24% of animals will need to experience more than three shocks, with the maximum number of footshocks that will be delivered ... Moderate: 76%. Severe: 24%. What will happen to animals -
Neuronal circuit mechanisms underlying cognitive memory judgements…
https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf30 Apr 2024: A typical study lasts between 12-24 months during which time a marmoset may receive approx. ... Such effects typically resolve within 2 hours but can extend to approximately 24 hours. -
Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …
https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf30 Apr 2024: PPL number: | Granted: 03 Jul 23 | Expires: 03 Jul 28. Downloaded: 9:27pm, 25 Apr 2024 Page 2 of 11. Objectives and benefitsDescription of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing. -
Determining mechanisms of tumour development and relapse following…
https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf29 Apr 2024: As the mice are checked daily, at most, a mouse would experience paralysis for no more than 24 hours. -
Understanding the cell biology behind cardiovascular diseases…
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_cell_biology_behind_cardiovascular_diseases_non-technical_summary_redacted.pdf30 Apr 2024: subcutaneous 20ml/kg 2 24. Exceptions to this would be thioglycollate IP, which needs to be given in 1ml (standard practice), and the HDTV injection. -
New treatments for renal and liver disease (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatments_for_renal_and_liver_disease_non-technical_summary_redacted.pdf30 Apr 2024: Even with timely dialysis, the death rates in patients with kidney failure vary from 20% to 50% over 24 months. -
Mechanisms controlling cell division and cell identity during…
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_cell_division_and_cell_identity_during_development_reprogramming_and_disease_redacted.pdf30 Apr 2024: These animals will be killed unless there are signs of recovery within 24 hours. -
Neural, physiological and behavioural mechanisms underlying cognition …
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf30 Apr 2024: A typical study lasts between 12-24 months during which time an animal may receive approx. ... Such effects typically resolve within 3 hours but can extend to approximately 24 hours. -
Development of humanised mouse models for study of cancer…
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf29 Apr 2024: In such cases, the animals will be culled if these clinical signs do not respond to treatment (such as high energy and easily digestible diet) and persist for up to 24
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