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She leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus. ... Viruses 3(11) 2192-2213. Kenyon JC, Lever AML (2011) XMRV, Prostate Cancer and Chronic Fatigue Syndrome.

27 Jun 2024: Cambridge Infectious Diseases - Addenbrooke's Hospital https://www.infectiousdisease.cam.ac.uk/departments/addenbrookes-hospital en Dr John Clark https://www.infectiousdisease.cam.ac.uk/staff/dr-john-clark <div class="field field-name-body field-type

23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution

12 May 2021: the process by which new variants likely arise, and also reporting the first data on Pfizer BioNTech vaccine-induced antibody responses against the B.1.1.7 ‘Kent UK’ variant. ... His research investigates the basis for pathological immune activation

27 Jun 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory

27 Jun 2024: CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. ... 2009). Multiple redundant stress resistance mechanisms are induced i<i>n Salmonella enterica </i>serovar Typhimurium<i> </i>in response to modulation

28 Jun 2024: 29875319.pdf" target="_blank">[PDF]</a></p> <p><a href="http://www.ncbi.nlm.nih.gov/pubmed/29540581" target="_blank"><b>Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes ... ncbi.nlm.nih.gov/pubmed/28530713" target="_blank"><b>BACH2

23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95.

22 Oct 2013: The researchers first examined genetic information from individuals who suffer from immunodeficiency and are predisposed to infections. ... The newly identified disease has been called Activated PI3K-δ Syndrome (APDS) after the enzyme that is affected

23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe