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Publications - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/research/publications/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Site Search. Site Search. Publications. Institute of Metabolic Science-Metabolic Research Laboratories. -
https://www.immunology.cam.ac.uk/taxonomy/term/77/feed
https://www.immunology.cam.ac.uk/taxonomy/term/77/feed23 Feb 2024: Endogenous NPCs subsequentlymigrate toward the ischemic lesion where they promote tissue remodelingand neural repair. ... Transplanted NPCs are thought to act mainlyvia trophic and immune modulatory effects thereby complementing the<br /> restorative -
Dr Cristina Rada | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/car%40mrc-lmb.cam.ac.uk23 Feb 2024: isotype switching. gene targeting. retrovirus. cell culture. fluorescence microscopy. somatic hypermutation. -
Professor Sir David Baulcombe FRS | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/baulcombe23 Feb 2024: The specific binding to 21-nt double-stranded RNAs is crucial for the anti-silencing activity of Cucumber vein yellowing virus P1b and perturbs endogenous small RNA populations. -
Economic and Social History at Cambridge
https://www.econsoc.hist.cam.ac.uk/academic_visitors.html7 Mar 2024: Progress in this area should shed light on the reasons for the stability and instability of the tax system, and should enable us to distinguish endogenous from exogenous factors. -
New publication | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/news/gilley-paper23 Feb 2024: NMNAT2 is an endogenous axon maintenance factor that preserves axon health by blocking Wallerian-like axon degeneration. -
Dr Nick Lynch | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/staff/dr-nick-lynch23 Feb 2024: In vivo biosynthesis of endogenous and of human C1 inhibitor in transgenic mice: tissue distribution and colocalization of their expression. -
Dr Nicole Kaneider | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/kaneider23 Feb 2024: However, GPR35’s endogenous, relevant ligands and its function remain enigmatic. Via specific, consciously designed and specific lipopeptides I aim to modulate GPR35 function to reveal its biological function, and will -
https://www.psychiatry.cam.ac.uk/blog/tag/alcohol/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/alcohol/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction. -
Chatterjee group - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/research/our-research-teams/chatterjee-group/23 Feb 2024: This knowledge led us to design a thyroid hormone analogue which dissociates a transcription repression complex from mutant TRα better than endogenous ligand, providing proof-of-principle for developing such compounds -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/11/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/11/feed23 Feb 2024: Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous peptide ligand. ... and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). -
Daniel Fazakerley - Institute of Metabolic Science-Metabolic Research …
https://www.mrl.ims.cam.ac.uk/research/principal-investigators/daniel-fazakerley-2/23 Feb 2024: A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology. -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/10/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/10/feed23 Feb 2024: Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous peptide ligand. ... and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). -
https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/26
https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/2623 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-02-06T11:14:05","modified_gmt":"2015-02-06T11:14:05","slug":"publications","status" -
https://www.psychiatry.cam.ac.uk/blog/tag/news-2/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/news-2/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction. -
Dr. Rachel Hewitt | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/rachel-hewitt23 Feb 2024: Frontiers in Immunology. 2017 | journal-article. PMID: 28367148DOI: 10.3389/fimmu.2017.00284. An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells. -
https://www.immunology.cam.ac.uk/taxonomy/term/66/feed
https://www.immunology.cam.ac.uk/taxonomy/term/66/feed23 Feb 2024: the anti-silencing activity of Cucumber vein yellowing virus P1b and perturbs endogenous small RNA populations.RNA. -
Professor Andrew Lever | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/amll1%40medschl.cam.ac.uk23 Feb 2024: Person keywords:. rotavirus. cell processes. RNA structure. retrovirus. RNA packaging. Contact us. -
https://www.immunology.cam.ac.uk/taxonomy/term/44/feed
https://www.immunology.cam.ac.uk/taxonomy/term/44/feed23 Feb 2024: Endogenous NPCs subsequentlymigrate toward the ischemic lesion where they promote tissue remodelingand neural repair. ... Transplanted NPCs are thought to act mainlyvia trophic and immune modulatory effects thereby complementing the<br /> restorative -
Stephen O'Rahilly - Institute of Metabolic Science-Metabolic…
https://www.mrl.ims.cam.ac.uk/research/principal-investigators/professor-sir-stephen-orahilly/23 Feb 2024: Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GD15. Proc Natl Acad Sci U S A. -
Production of VSV-G retroviral virus by CaCl2 Transfection | Ron Lab
https://ron.cimr.cam.ac.uk/production-vsv-g-retroviral-virus-cacl2-transfection23 Feb 2024: Search site. Ron Lab. Production of VSV-G retroviral virus by CaCl2 Transfection. Production of VSV-G retroviral virus by CaCl2 Transfection. Starting Material – 293T Cells. Plasmids: pJK3. pCMV-tat-HIV. pL-VSV-G. Specific DNA (pBabe plasmid). -
Peptidomics and Proteomics Core - Institute of Metabolic…
https://www.mrl.ims.cam.ac.uk/research/core-facilities/peptidomics_and_proteomics-core-facility/23 Feb 2024: Bioinformatics analyses are performed using PEAKS, capable of performing normal proteomics experiments, and identifying endogenous peptides of up to 65 amino acids in length. ... Peptidomic analysis of endogenous plasma peptides from patients with -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/46/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/46/feed23 Feb 2024: Cambridge Cardiovascular - Department of Pharmacology https://www.cardiovascular.cam.ac.uk/institutions/dir-pharmacology en Dr Lay Ping Ong https://www.cardiovascular.cam.ac.uk/staff/dr-lay-ping-ong <div class="field field-name-field-sd-consultancy -
Dr Stefano Pluchino | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/spp24%40cam.ac.uk23 Feb 2024: We have identified a new complementary mechanism by which directly induced NSCs (iNSCs) respond to endogenous inflammatory metabolic signals to inhibit the activation of type-1 mononuclear phagocytes (MPs) in vivo -
https://www.psychiatry.cam.ac.uk/blog/tag/addiction/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/addiction/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction. -
Research Projects - Department of Clinical Neurosciences
https://www-neurosciences.medschl.cam.ac.uk/workandstudy/postgraduate-training/research-projects/23 Feb 2024: co-supervised with A Nicaise and I Mohorianou). Recent work suggests that cellular ageing, known as senescence, of endogenous stem-like cells in the brain may contribute to the chronic inflammation ... We have developed a novel RABID sequencing-based -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/28/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/28/feed23 Feb 2024: Cambridge Cardiovascular - Department of Biochemistry https://www.cardiovascular.cam.ac.uk/institutions/dir-biochemistry en Dr Aishwarya Jacob https://www.cardiovascular.cam.ac.uk/staff/dr-aishwarya-jacob <div class="field field-name-body -
Dr Su Metcalfe | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/smm1001%40cam.ac.uk23 Feb 2024: only promotes survival but also supports tissue integration; and (iii) promoting endogenous stem and precursor cells in situ. -
https://www.medschl.cam.ac.uk/category/newsletter/newsletter-issue-23/…
https://www.medschl.cam.ac.uk/category/newsletter/newsletter-issue-23/feed/23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute -
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction. -
Neuroinflammation & MS - Department of Clinical Neurosciences
https://www-neurosciences.medschl.cam.ac.uk/research/immune-dysfunction-in-the-nervous-system/23 Feb 2024: Previously we showed that bexarotene, a licensed retinoid X receptor gamma agonist, promotes endogenous brain repair, but was too toxic to be given to people with MS. -
Dr Nunzio Iraci | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/dr-nunzio-iraci23 Feb 2024: v) Target cells require endogenous Stat1 and Ifngr1 to activate Stat1 signalling. -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/55/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/55/feed23 Feb 2024: a href="https://www.ncbi.nlm.nih.gov/pubmed/28293165" target="_self">[Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide -
https://www.psychiatry.cam.ac.uk/blog/tag/valerie-voon/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/valerie-voon/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction. -
https://www.immunology.cam.ac.uk/taxonomy/term/48/feed
https://www.immunology.cam.ac.uk/taxonomy/term/48/feed23 Feb 2024: In vivo biosynthesis of endogenous and of human C1 inhibitor in transgenic mice: tissue distribution and colocalization of their expression. ... PMID: 28367148DOI: 10.3389/fimmu.2017.00284</p> <p></p> <p>An endogenous nanomineral chaperones luminal -
Dr Janet Maguire - Experimental Medicine and Immunotherapeutics (EMIT)
https://emit.medschl.cam.ac.uk/people/investigators/dr-anthony-davenport/dr-janet-maguire/23 Feb 2024: Pyr. 1. ]apelin-13. (1–12). is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr. ... Elabela/Toddler is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration -
Dr Joseph Cheriyan - EMIT
https://emit.medschl.cam.ac.uk/people/investigators/dr-joseph-cheriyan/23 Feb 2024: Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13. -
https://www.medschl.cam.ac.uk/category/schoolnews/research-news/otr/fe…
https://www.medschl.cam.ac.uk/category/schoolnews/research-news/otr/feed/23 Feb 2024: p strongIdentification of Endogenous and Surrogate Ligands for Orphan GPCRs – Through Computational Drug Design Methods/strongbr / David Gloriam, Associate Professor, Department of Drug Design and Pharmacology, University of Copenhagen/p p -
https://www.med.cam.ac.uk/morrell/wp-json/wp/v2/pages/26
https://www.med.cam.ac.uk/morrell/wp-json/wp/v2/pages/2623 Feb 2024: R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, strongMorrell NW/strong, Maguire JJ, Davenport AP.u00a0 Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in -
https://www.phpc.cam.ac.uk/gerontology/wp-json/wp/v2/pages/18
https://www.phpc.cam.ac.uk/gerontology/wp-json/wp/v2/pages/1824 Feb 2024: Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition ( EPIC ). Endocr Relat Cancer. 2008 Jun;15(2):485-497./lin/ulnulnliRohrmann S, ... Endogenous androgens and risk of -
Professor Kevin Brindle FMedSci FRS | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/kmb1001%40cam.ac.uk23 Feb 2024: The relationship between endogenous thymidine concentrations and F-18 FLT uptake in a range of preclinical tumour models. -
SARM1 activation and blocking | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/blog/sarm1-activation-and-blocking23 Feb 2024: An elevated NMN:NAD ratio favours SARM1 activation. A preprint from our collaborators in Italy reports that this holds at physiological levels of both metabolites, and that there are additional endogenous -
https://www.immunology.cam.ac.uk/taxonomy/term/40/feed
https://www.immunology.cam.ac.uk/taxonomy/term/40/feed23 Feb 2024: Cambridge Immunology Network - CITIID https://www.immunology.cam.ac.uk/departments/cambridge-institute-for-therapeutic-immunology-infectious-disease Cambridge Institute of Therapeutic Immunology and Infectious Disease en Professor Ravindra Gupta -
New vaccine targets for a neglected malaria parasite | Cambridge…
https://www.cimr.cam.ac.uk/research-advances/new-vaccine-targets-neglected-malaria-parasite23 Feb 2024: The researchers also leveraged the genetic plasticity of P.knowlesi by using CRISPR-Cas9 to create P.knowlesi lines in which endogenous genes had been exchanged with their P. -
Dr Jonathan Dodd | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/jonathan.dodd%40cimr.cam.ac.uk23 Feb 2024: Endogenous IL-21 regulates pathogenic mucosal CD4 T-cell responses during enhanced RSV disease in mice. -
https://www.immunology.cam.ac.uk/taxonomy/term/12/feed
https://www.immunology.cam.ac.uk/taxonomy/term/12/feed23 Feb 2024: In vivo biosynthesis of endogenous and of human C1 inhibitor in transgenic mice: tissue distribution and colocalization of their expression. -
Tissue and Cell Imaging (TCI) Core - Institute of Metabolic…
https://www.mrl.ims.cam.ac.uk/research/core-facilities/tissue-and-cell-imaging-tci-core/23 Feb 2024: A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology. -
Retroviruses integrate into a shared, non-palindromic DNA motif - MRC …
https://www.mrc-bsu.cam.ac.uk/blog/retroviruses-integrate-into-a-shared-non-palindromic-dna-motif/23 Feb 2024: understand how this integration is targeted — how does the retrovirus “choose” where to insert its genetic material? -
https://www.immunology.cam.ac.uk/taxonomy/term/24/feed
https://www.immunology.cam.ac.uk/taxonomy/term/24/feed23 Feb 2024: In vivo biosynthesis of endogenous and of human C1 inhibitor in transgenic mice: tissue distribution and colocalization of their expression. -
https://www.immunology.cam.ac.uk/taxonomy/term/58/feed
https://www.immunology.cam.ac.uk/taxonomy/term/58/feed23 Feb 2024: p> <p></p> <p><strong>Our key goals are to understand:</strong><br /> </p> <p> -how cells distinguish viral from endogenous nucleic acids<br /> -how the immune response against double-stranded
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