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23 Feb 2024: necrosis factor-alpha therapy for severe enteropathy in patients with common variable immunodeficiency (CVID). ... The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to

23 Feb 2024: Search site. Cambridge Immunology Network. Professor Jonathan Luke Heeney. Vaccine induced immunity. ... Immune correlates of natural and vaccine induced immunity. Viral evasion of host responses.

23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating

23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests:&nbsp;</div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire

23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution

23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe

23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS.

23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38. ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

23 Feb 2024: JA, Lehner PJ (2014) TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. ... and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study.<span>Lancet</span>.

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require

23 Feb 2024: Cambridge Immunology Network - Immunogenetics https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/immunogenetics The complex effects of genotype on phenotype in immunology Every immunologist makes use of genetics at some level but the

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... blank">Simian Immunodeficiency Virus envelope glycoprotein

23 Feb 2024: Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. ... Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.