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Understanding TRIM21 activation allows Trim-Away toolbox expansion -…
https://www2.mrc-lmb.cam.ac.uk/understanding-trim21-activation-allows-trim-away-toolbox-expansion/9 Mar 2021: In fact, this may explain why TRIM21 evolved this requirement for clustering as anything entering the cell coated with multiple antibodies must require a quick response and degradation.
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ProSHADE: ProSHADE_internal::ProSHADE_distances Class Reference
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d1/d6f/class_pro_s_h_a_d_e__internal_1_1_pro_s_h_a_d_e__distances.html1 Nov 2018: It returns a vector of vectors of energy level distances from the fragment to all passing database entries. ... It returns a vector of vectors of trace sigma distances from the fragment to all passing database entries. -
30 Apr 2004 18:9 AR AR214-BB33-09.tex AR214-BB33-09.sgm…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2004.pdf1 May 2004: have similar, almost exchangeable functions, asdemonstrated recently by a gain-of-function point mutation in FtsA that removesthe requirement for ZipA completely (45). ... maritima(Figure 10). The protein was found to polymerizeeasily under mild -
Opening of LMB Containment Level 3 lab fast-tracked to help fight the …
https://www2.mrc-lmb.cam.ac.uk/opening-of-lmb-containment-level-3-lab-fast-tracked-to-help-fight-the-covid-19-pandemic/23 Oct 2020: sure the laboratory met all legal requirements. ... Leo: In the context of COVID-19, everyone is looking at the spike protein – which coats the outside of the virus particle and mediates cell entry – and how spike antibodies stop
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PII: S0014-5793(01)02216-5
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MinD%20FEBS.pdf5 Mar 2001: 3. Results. Structurally MinD closely resembles other nucleotide bind-ing proteins such as nitrogenase iron proteins and GTPasessuch as Ffh (PBD entry 1NG1 [20]), part of the signal recog-nition particle ... The nucleotide binding surface of MinD is the -
Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: collar, may facilitate substrate entry and possibly also. help with translocation into the AAA+ channel. ... tral channel, which possibly facilitates the entry of cer-. tain substrates (and itself). -
Bacterial chromosome segregation: structure andDNA binding of the Soj …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/soj_embo2005.pdf30 Jan 2005: confirming that ATP-dependent dimerisation is the critical. requirement for assembly of the protein onto DNA (Figure. ... domains dimerise, a requirement for HTH-mediated DNA. binding (Leonard et al, 2004). -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: Functional Requirements. Having determined the assembly and subcellular organization of CreS, we next addressed the molecular determinants of CreS- dependent cell curvature generation. ... Nevertheless, correct CreS assembly is not the only functional -
Bacterial actin MreB assembles in complex with cell shape protein RodZ
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf17 Feb 2010: superposition on the DNA complex of phage 343 repressor. (PDB entry 2or1; Aggarwal et al, 1988). ... Colour code as in (B). Double-stranded DNA in grey (taken from pdb entry 2OR1). -
PII: S1388-1981(99)00150-X
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10570253.pdf20 Apr 2002: from PLC-N1 (pdb entry code 1MAI) was determined independently of the structure of theremainder of the enzyme (pdb entry code 2ISD). ... Sequence analysis suggests that. Fig. 7. The C2 domain. The C2 domains from PLC-N1 and PKCL (pdb entry code 1A25) are
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