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PII: S1388-1981(99)00150-X
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10570253.pdf20 Apr 2002: from PLC-N1 (pdb entry code 1MAI) was determined independently of the structure of theremainder of the enzyme (pdb entry code 2ISD). ... Sequence analysis suggests that. Fig. 7. The C2 domain. The C2 domains from PLC-N1 and PKCL (pdb entry code 1A25) are -
30 Apr 2004 18:9 AR AR214-BB33-09.tex AR214-BB33-09.sgm…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2004.pdf1 May 2004: have similar, almost exchangeable functions, asdemonstrated recently by a gain-of-function point mutation in FtsA that removesthe requirement for ZipA completely (45). ... maritima(Figure 10). The protein was found to polymerizeeasily under mild -
PII: S0166-2236(03)00131-0
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/25_Hegde_RS_TINS_2003.pdf30 Jun 2003: neurodegeneration [1]. Yet, all heritable and transmissibleprion diseases seem to share certain characteristicpathological changes and an obligate requirement forPrP expression, suggesting at least some common aspectsto their pathogenesis. -
Molecular mechanism and physiological functions of clathrin-mediated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/McMahon%20NRMB%202011.pdf19 Jul 2011: In this case, the clathrin lattice may serve as a signalling platform for actin polymerization, which may thus make it indispen sible for cellular entry of these very large cargoes. ... The pathway is also exploited by toxins, viruses and bacteria to -
PII: S0014-5793(01)02216-5
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MinD%20FEBS.pdf5 Mar 2001: 3. Results. Structurally MinD closely resembles other nucleotide bind-ing proteins such as nitrogenase iron proteins and GTPasessuch as Ffh (PBD entry 1NG1 [20]), part of the signal recog-nition particle ... The nucleotide binding surface of MinD is the -
nature14896 493..505
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/95_Brown_A_Nature_2015.pdf19 Aug 2015: In the structures here, the essentialNIKS sequence (residues 61–64)21, located at the end of helix a2,imposes a requirement for uridine in the first (11) position via inter-actions ... Purines would be disfavoured at the 11 position by steric -
Structural and Mechanistic Comparison of Prokaryotic and Eukaryotic…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9466937.pdf15 Jan 1998: Results and Discussion. The PI-PLC fold. The crystal structures of PI-PLC from Bacilluscereus (bPI-PLC; PDB entry code 1PTD) and PI-. ... entry ofphospholipid head groups into the active site orthe release of product following catalysis. -
Protein-driven membrane stresses in fusion and fission
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovCurvature2010.pdf21 Feb 2011: Proteins as energy generators for membraneremodelingMembrane remodeling, either by fusion or fission, canoccur if two physical requirements are fulfilled. ... Thereare two important requirements for this mechanism ofmembrane fusion. First, the -
Protein-driven membrane stresses in fusion and fission
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Kozlov%20Trends%20Biochem%20Sci%202010.pdf20 Nov 2010: Proteins as energy generators for membraneremodelingMembrane remodeling, either by fusion or fission, canoccur if two physical requirements are fulfilled. ... Thereare two important requirements for this mechanism ofmembrane fusion. First, the -
Bacterial actin MreB assembles in complex with cell shape protein RodZ
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf17 Feb 2010: superposition on the DNA complex of phage 343 repressor. (PDB entry 2or1; Aggarwal et al, 1988). ... Colour code as in (B). Double-stranded DNA in grey (taken from pdb entry 2OR1).
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