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Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: collar, may facilitate substrate entry and possibly also. help with translocation into the AAA+ channel. ... tral channel, which possibly facilitates the entry of cer-. tain substrates (and itself). -
01Eichler(Hedge)
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/33_Hegde_RS_Chapter_2005.pdf31 Oct 2005: By contrast, translocation into the ER (open arrow) is often regarded as a constitutive process wherethe presence of a signal sequence in a protein predetermines its entry into the ER. ... Thus, the entry of proteins into the ER is not necessarilya -
Structure of the hexagonal surface layer on Caulobacter crescentus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/s-layer-nmicrobiol201759.pdf6 Apr 2017: All residues in the RsaA249–1026 X-ray structure are well ordered,reflecting a requirement that the S-layer lattice must avoid flexibleloops, as they would be easy targets for hostile ... Despite forming a con-tinuous sheet, there is a requirement for -
Dynamic Filaments of the Bacterial Cytoskeleton
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2006.pdf19 Apr 2006: arrow). (center,top) Note the closed conformation (PDB entry 1MWM) and (bottom) the open conformation of the apoand ADP-bound forms of ParM, both from E. ... right) AMPPNP-bound FtsA from T. maritima (PDB entry 1E4G)(136). www.annualreviews.org • -
Quality and quantity control at the endoplasmic reticulum
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/65_Hegde_RS_COCB_2010.pdf7 Jun 2010: Given the ability of certain proteins to insert in,and possibly traverse the lipid bilayer spontaneously, withno essential requirement for membrane proteins demon-strated [34], alternatives to protein-conducting channelsshould probably ... 20! Bernasconi -
The mechanisms of integral membrane protein biogenesis
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf22 Sep 2021: The minimum requirement for SRP recognition is a predominantly hydrophobic sequence of approximately seven amino acids. ... e | Tail- anchored (TA) protein insertion by the guided entry of TA protein (GET) pathway. -
mmi_3991.fm
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ftsn2004.pdf15 Apr 2004: The requirement of FtsN for cell division in. E. coli. became obvious with a conditional null allele of the. ... Residues A127-L132apparently contribute a fourth helix, the Table entries forwhich are italicized here because they involve non-nativeresidues -
Bacterial chromosome segregation: structure andDNA binding of the Soj …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/soj_embo2005.pdf30 Jan 2005: confirming that ATP-dependent dimerisation is the critical. requirement for assembly of the protein onto DNA (Figure. ... domains dimerise, a requirement for HTH-mediated DNA. binding (Leonard et al, 2004). -
The structure of human thyroglobulin
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TG_Nature2020.pdf31 Jan 2020: To validate our list of requirements for hormonogenesis from poly-peptide chains, we set out to engineer synthetic T4 hormonogenic sites into the unrelated bacterial MBP. ... 4. Cahnmann, H. J., Pommier, J. & Nunez, J. Spatial requirement for coupling of -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: Functional Requirements. Having determined the assembly and subcellular organization of CreS, we next addressed the molecular determinants of CreS- dependent cell curvature generation. ... Nevertheless, correct CreS assembly is not the only functional
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