Search

4 Jan 2018: This result suggests that the critically important p53 stress response in stem cells fundamentally differ from the response seen in other cells. ... In addition, the new insight into the function of p53 in blood stem cells may explain why certain blood

17 Sep 2020: 2020) A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation Stem Cell Reports 32888504.

24 Sep 2010: Alan will continue to lead his research on the p53 tumour suppressor protein at the LMB with an MRC programme grant for the next five years.

4 Aug 2020: Alan’s most recent interest is in the tumour suppressor p53, with the aim to understand how mutations affect its function, so that novel anti-cancer drugs may be designed to

Chin, W. Fischle, S.M. Gasser. Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.

24 Nov 2021: Inset, model of the molecular mechanism by which ADH5 and CSB cooperate to protect cells from damage, which is sensed by the stalled transcription machinery and can trigger p53 dependent activation

Chin, W. Fischle, S.M. Gasser. (53) Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.

Fischle, S.M. Gasserem. u00a0/em/pnpstrongAcetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration./strongbr /na

3 Apr 2024: Fischle, S.M. Gasserem. /em/p p(53)strongAcetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration./strongbr / a

Fischle, S.M. Gasserem. u00a0/em/pnp(53)u00a0strongAcetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration./strongbr /na

22 Oct 2002: Johnstone, R.W., Ruefli, A.A., and Lowe, S.W. (2002). Cell 108,roles of Rb and p53 and provides molecular clues as to 153–164.how these famous tumor suppressors ... 2000). Carcinogenesis 21, 485–495.regulatory pathway involving p53, Rb, BH3-only

12 Nov 2006: pro-survival molecule BclXL. Similar negative regulation of YAP (not. shown) leads to repression of the p53 related transcription factor p73. ... reciprocal changes in the classic NF-kB pro-survival pathway and the. pro-apoptotic p53 pathway.

11 Nov 1999: Barrett, J. C. Differential regulation of p21 by p53 and Rb in cellular. ... et al. Involvement of p85 in p53-dependent apoptotic response to oxidative stress.

19 Nov 2019: Krstic-Demonacos, N. B. La Thangue, A TPR motif cofactor contributes to p300 activity in the p53 response. ... Knapp, N. B. La Thangue, A. N. Bullock, The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.

12 Nov 2009: 2007) G10, G11 i. CRY P53 domain 6.5 27.0 CPE, Joel Kaar &Nicolas Basse.

16 Oct 2009: early in DNA damage response and regulateRAP80 localization. Many cell cycle checkpoint proteins, includingATM, Chk2, BRCA1, and p53, play critical rolesin the maintenance of genomic stability.

29 Jan 2024: Chin, W. Fischle, S.M. Gasser. EMBO J. 2011. 30: 2610-2621. (53) Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.

19 Dec 2016: By default, the applet shows details of a test Delta screen (Delta screen p53) which contains PEG3350 as precipitant, glycerol as cryoprotectant, etc. ... In Delta screen p53, component 7 is a cryoprotectant (glycerol). The concentration of

1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and

22 Jul 2007: with KRAS (G13D) and P53(S241F) mutations). These lines. were infected with retrovirus expressing iDab#6-memb, and.