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21 - 30 of 74 search results for news |u:www.ubs.admin.cam.ac.uk

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  2. Development of humanised mouse models for study of cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf
    29 Apr 2024: This could lead to development of new therapies that are more effective and cause fewer side effects to patients. ... More specifically, we expect to generate at least one new therapy and advance it to a stage that it can be investigated further in large

  3. PK and PKPD studies to support Respiratory and Immunology research

    https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf
    30 Apr 2024: To enable us to decide what doses of new treatments we need to use in our respiratory and immunology disease models. ... There are multiple stages of non-animal screening of new molecules that are in place before testing in rodent.

  4. Discovery and development of treatments for immunological diseases

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf
    29 Apr 2024: goal by enabling us to test new therapeutic hypothesis in vivo relevant to new treatments for immune mediate diseases. ... This de-risks again the potential for using new therapeutic agents which are unlikely to achieve active concentrations at the

  5. Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf
    30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... We also expect, in the medium term, that our research will lead to the development of new behavioural treatments.

  6. Proteotoxicity in development and ageing (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf
    30 Apr 2024: There is no cure for neurodegenerative disorders and thus, finding a new common target is at utmost importance. ... We have created new mouse lines with specific mutations in genes that disrupt one of the stress response pathway that is called

  7. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: Discoveries made on new bacterial species will be published and available to other researchers. ... We continuously consider their use and development in light of new experimental data.

  8. Development of Molecular Imaging and Theranostic Agents for Cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf
    30 Apr 2024: Some of these methods are aimed at providing information to develop new therapies for these diseases. ... We are developing new ways to image cancer and inflammation and find novel ways of treating these diseases.

  9. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: For breeding design we use several online resources, especially when bringing in a new strain. ... care for our strains and to identify any new and better treatments that could be utilised.

  10. Gut hormone modulation of metabolism (non-technical summary)_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/gut_hormone_modulation_of_metabolism_non-technical_summary_redacted.pdf
    30 Apr 2024: Our findings should guide these attempts and clarify the mechanisms of action these new therapies employ. ... When animals are exposed to new diets or environments they receive training sessions.

  11. Embryonic origins of heart disease

    https://www.ubs.admin.cam.ac.uk/system/files/public/embryonic_origins_of_heart_disease_non-technical_summary_redacted.pdf
    29 Apr 2024: The new bedding material generated much less dust. What published best practice guidance will you follow to ensure experiments are conducted inthe most refined way? ... Therefore, the project licence holder will have regular discussions with the Named

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