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Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models…
https://www2.mrc-lmb.cam.ac.uk/marta-shahbazi-wins-2019-3rs-prize-for-applying-new-in-vitro-models-to-study-early-embryo-development/12 Jun 2020: Search this website. Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development. ... Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development.
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Ankyrins: a missing molecular link in mechanical senses - MRC…
https://www2.mrc-lmb.cam.ac.uk/ankyrins-a-missing-molecular-link-in-mechanical-senses/22 Apr 2020: Hearing and touch depend on the ability of sensory neurons to be activated by a force, such as pressure or vibration from sound, and then pass information on to the brain. William Schafer’s group has identified some of the key proteins that make
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TRIM21 links antibody and T cell immunity to combat viral infection - …
https://www2.mrc-lmb.cam.ac.uk/trim21-links-antibody-and-t-cell-immunity-to-combat-viral-infection/4 Dec 2020: This reveals a new mechanism of immune synergy between antibodies and T cells, which are often thought to work quite separately. ... Therefore, this work provides multiple new concepts that could be exploited in the development of treatments for and
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Coot Cryo-EM Tutorial 2: Fitting and Mutating | Coot Development Blog
https://www2.mrc-lmb.cam.ac.uk/coot/blog/2020/10/20/Coot-Cryo-EM-main.html20 Oct 2020: Compare this maps with the original. You should find that the new (smooth) map is easier to understand. ... use the Display Manager to delete the first (mrc) map. Change the contour Step for the new Maps:. -
High-resolution structure of a GPCR-arrestin complex - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/first-high-resolution-structure-of-a-gpcr-arrestin-complex/17 Jun 2020: Understanding minute structural differences in (G protein-coupled receptor) GPCR complexes could lead to the design of more efficacious drugs that have fewer side effects
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A connection between stress detection and lifestyle decisions in…
https://www2.mrc-lmb.cam.ac.uk/a-connection-between-stress-detection-and-lifestyle-decisions-in-worms/24 Nov 2020: Rebecca Taylor’s group has identified a signalling molecule that connects detection of a stressful environment by the nervous system with molecular defence mechanisms in other tissues and leads to changes in feeding behaviour and reproduction.
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A map to show the way to sense smell, temperature, and humidity - MRC …
https://www2.mrc-lmb.cam.ac.uk/a-map-to-show-the-way-to-sense-smell-temperature-and-humidity/23 Jul 2020: Producing maps of how neurons connect with each other (connectomes) allows scientists to build and test theories of brain function. Greg Jefferis’ group have presented the first full map of olfactory, thermosensory, and hygrosensory projection
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A synthetic molecule that can restore lost connections in the brain - …
https://www2.mrc-lmb.cam.ac.uk/a-synthetic-molecule-that-can-restore-lost-connections-in-the-brain/28 Aug 2020: The brain contains an enormous number of connections, known as synapses. Their loss is associated with many disorders. Radu Aricescu’s group and collaborators in Japan and Germany have designed a molecule that restores synapses in animal disease
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Opening of LMB Containment Level 3 lab fast-tracked to help fight the …
https://www2.mrc-lmb.cam.ac.uk/opening-of-lmb-containment-level-3-lab-fast-tracked-to-help-fight-the-covid-19-pandemic/23 Oct 2020: I have also started working on a new project with Radu Aricescu and Jan Löwe to test new vaccine candidates. ... chip model to understand the immune response to Mycobacterium tuberculosis and develop new drug treatments.
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Structures of virus-like capsids involved in learning and memory…
https://www2.mrc-lmb.cam.ac.uk/structures-of-virus-like-capsids-involved-in-learning-and-memory-formation/23 Jan 2020: The neuronal gene Arc plays important roles in neural plasticity, learning and memory-related molecular processes and has been shown to mediate intercellular RNA transfer by forming viral-like capsids. John Briggs’ group has now solved the first
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