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11 - 20 of 70 search results for news |u:www2.mrc-lmb.cam.ac.uk

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  2. How two proteins work together in DNA damage detection - MRC…

    https://www2.mrc-lmb.cam.ac.uk/how-two-proteins-work-together-in-dna-damage-detection/
    Thumbnail for How two proteins work together in DNA damage detection - MRC Laboratory of Molecular Biology 7 Feb 2020: These new structures, and the concomitant increased understanding of how PARPs create the ADP-ribosylation that initiates DNA repair processes, could potentially lead to improvements in PARP inhibitor efficacy and novel
    By: pmabbs, @MRC_LMB

  3. How cells avoid and resolve ribosome traffic jams - MRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/how-cells-avoid-and-resolve-ribosome-traffic-jams/
    Thumbnail for How cells avoid and resolve ribosome traffic jams - MRC Laboratory of Molecular Biology 16 Jul 2020: Ribosome collisions along an mRNA ‘road’ relay a message to stop new ribosomes from entering while a tow truck clears the wreckage. ... To maximise efficiency, new ribosomes start translating an mRNA before previous ones have finished.
    By: pmabbs, @MRC_LMB

  4. A new layer of complexity in GPCR signalling could explain…

    https://www2.mrc-lmb.cam.ac.uk/a-new-layer-of-complexity-in-gpcr-signalling-could-explain-differences-in-receptor-function-and-drug-response/
    Thumbnail for A new layer of complexity in GPCR signalling could explain differences in receptor function and drug response - MRC Laboratory of Molecular Biology 5 Nov 2020: A new layer of complexity in GPCR signalling could explain differences in receptor function and drug response. ... Nature. Nature News & Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,.
    By: pmabbs, @MRC_LMB

  5. A novel tau fold in the neurodegenerative disease corticobasal…

    https://www2.mrc-lmb.cam.ac.uk/a-novel-tau-fold-in-the-neurodegenerative-disease-corticobasal-degeneration/
    Thumbnail for A novel tau fold in the neurodegenerative disease corticobasal degeneration - MRC Laboratory of Molecular Biology 13 Feb 2020: These new structures also reveal the presence of additional molecules in a cavity within the filament. ... patients. Understanding how and why tau assembles into different disease-specific structures will also be beneficial for the development of new
    By: pmabbs, @MRC_LMB

  6. First structure of a fungal GPCR - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/first-structure-of-a-fungal-gpcr/
    Thumbnail for First structure of a fungal GPCR - MRC Laboratory of Molecular Biology 2 Dec 2020: Design of new, improved drugs with fewer side-effects requires a fuller understanding of their structures.
    By: pmabbs, @MRC_LMB

  7. Scientific collaboration to focus on search for new, improved…

    https://www2.mrc-lmb.cam.ac.uk/scientific-collaboration-to-focus-on-search-for-new-improved-detectors-for-low-energy-cryo-em/
    Thumbnail for Scientific collaboration to focus on search for new, improved detectors for low energy cryo-EM - MRC Laboratory of Molecular Biology 11 Mar 2020: Scientific collaboration to focus on search for new, improved detectors for low energy cryo-EM. ... detector was essential to fully realise the potential of the new microscope design.
    By: pmabbs, @MRC_LMB

  8. How is the Fanconi Anaemia pathway activated to remove DNA lesions? - …

    https://www2.mrc-lmb.cam.ac.uk/how-is-the-fanconi-anaemia-pathway-activated-to-remove-dna-lesions/
    Thumbnail for How is the Fanconi Anaemia pathway activated to remove DNA lesions? - MRC Laboratory of Molecular Biology 17 Feb 2020: New study, led by Pablo Alcón and Shabih Shakeel in Lori Passmore’s group, in collaboration with KJ Patel in the PNAC Division, uncovers a unique molecular “clamp and pin” mechanism that activates the D2l complex, which then recruits enzymes
    By: Matthew Fry, @MRC_LMB, @MRC_LMB

  9. A simple, novel mechanism to safeguard the integrity of the human…

    https://www2.mrc-lmb.cam.ac.uk/a-simple-novel-mechanism-to-safeguard-the-integrity-of-the-human-genome/
    Thumbnail for A simple, novel mechanism to safeguard the integrity of the human genome - MRC Laboratory of Molecular Biology 21 Aug 2020: To provide a comprehensive analysis of all possible STR permutations, Pierre, working with Guillaume Guilbaud also from Julian’s group, developed a new high-throughput assay that allows measurement of DNA
    By: pmabbs, @MRC_LMB

  10. LMB Band 6 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/research/animal-research/lmb-band-6/
    Thumbnail for LMB Band 6 - MRC Laboratory of Molecular Biology 21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. LMB Band
    By: @MRC_LMB

  11. Ribosomal rescue in our mitochondria - MRC Laboratory of Molecular…

    https://www2.mrc-lmb.cam.ac.uk/ribosomal-rescue-in-our-mitochondria/
    Thumbnail for Ribosomal rescue in our mitochondria - MRC Laboratory of Molecular Biology 27 Nov 2020: Mitochondrial ribosomes are different from those in the cytoplasm of human cells and little is known about their quality control. Venki Ramakrishnan’s group has discovered a novel pathway to rescue stalled mitoribosomes and determined structures
    By: pmabbs, @MRC_LMB

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