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  2. Uncovering the structure of the serotonin receptor - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/uncovering-the-structure-of-the-serotonin-receptor/
    Thumbnail for Uncovering the structure of the serotonin receptor - MRC Laboratory of Molecular Biology 21 Jun 2018: Understanding the activation mechanism of the serotonin receptor and the mode of binding of a failed anti-migraine drug, donitripan, will hopefully aid the development of new and improved drugs. ... Comparing the new G. o. -receptor structure to other
  3. Tau filament structures differ between neurodegenerative diseases -…

    https://www2.mrc-lmb.cam.ac.uk/tau-filament-structures-differ-between-neurodegenerative-diseases/
    Thumbnail for Tau filament structures differ between neurodegenerative diseases - MRC Laboratory of Molecular Biology 30 Aug 2018: These new structures show how tau folds in disease-specific ways, providing evidence for the hypothesis that different molecular structures of filamentous tau give rise to the diversity of symptoms between ... Comparison of the new structures of
  4. How the earliest life on Earth may have replicated itself - MRC…

    https://www2.mrc-lmb.cam.ac.uk/how-the-earliest-life-on-earth-may-have-replicated-itself/
    Thumbnail for How the earliest life on Earth may have replicated itself - MRC Laboratory of Molecular Biology 16 May 2018: He then engineered the best version to be able to copy pieces of itself, and assemble them together into new full synthetic copies. ... This new synthetic biology of triplet based RNA replication might also have biotechnological applications, such as
  5. Max Perutz Lecture to be given by Eric Gouaux - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-eric-gouaux/
    Thumbnail for Max Perutz Lecture to be given by Eric Gouaux - MRC Laboratory of Molecular Biology 22 Nov 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
  6. Understanding how TRIM21 is regulated during viral infection - MRC…

    https://www2.mrc-lmb.cam.ac.uk/understanding-how-trim21-is-regulated-during-viral-infection/
    Thumbnail for Understanding how TRIM21 is regulated during viral infection - MRC Laboratory of Molecular Biology 19 Apr 2018: New work from Leo James’ group in the LMB’s PNAC Division has now revealed how TRIM21 is regulated so that it is only switched on at the right time. ... In addition, Leo’s lab has recently developed a new technique, ‘TrimAway’, which uses
  7. Uncovering how alcohol-derived metabolites damage the genome of stem…

    https://www2.mrc-lmb.cam.ac.uk/uncovering-alcohol-derived-metabolites-damage-genome-stem-cells/
    Thumbnail for Uncovering how alcohol-derived metabolites damage the genome of stem cells - MRC Laboratory of Molecular Biology 4 Jan 2018: This new research has several implications for human health. It provides a simple explanation for how alcohol, which is a source of acetaldehyde, causes genetic damage and therefore acts as a ... In addition, the new insight into the function of p53 in
  8. Minutes of the CCP4 Ligands Meeting March 2018

    https://www2.mrc-lmb.cam.ac.uk/coot/ligands/minutes-ccp4-ligands-meeting-march-2018.html
    23 Mar 2018: Briefly mentioned Coot's new N-linked carbohydrate builder. Note: we are using latest CCP4 expert version. ... But new users will be confused. AP: PE to investigate making some videos.
  9. Controlling actin polymerisation in clathrin mediated endocytosis -…

    https://www2.mrc-lmb.cam.ac.uk/controlling-actin-polymerisation-in-clathrin-mediated-endocytosis/
    Thumbnail for Controlling actin polymerisation in clathrin mediated endocytosis - MRC Laboratory of Molecular Biology 7 Jun 2018: The molecular details elucidated by this new research may open avenues to develop drugs to fight infections and to design complementary therapeutic strategies for some types of cancers.
  10. Reversing a decline in cellular transport in ageing nerve cells - MRC …

    https://www2.mrc-lmb.cam.ac.uk/reversing-a-decline-in-cellular-transport-in-ageing-nerve-cells/
    Thumbnail for Reversing a decline in cellular transport in ageing nerve cells - MRC Laboratory of Molecular Biology 29 Mar 2018: This work opens new avenues for attempting to manipulate transport in a therapeutic setting.
  11. How cells selectively enhance gene expression in response to stress - …

    https://www2.mrc-lmb.cam.ac.uk/how-cells-selectively-enhance-gene-expression-in-response-to-stress/
    Thumbnail for How cells selectively enhance gene expression in response to stress - MRC Laboratory of Molecular Biology 5 Sep 2018: In order to make new proteins, genes are first transcribed to produce messenger RNA (mRNA) molecules, that are then translated into proteins. ... This means that this new role for tRNAs in the control of gene expression could have a role in human disease.

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