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  2. Understanding the maternal age effect in human oocytes - MRC…

    https://www2.mrc-lmb.cam.ac.uk/understanding-the-maternal-age-effect-in-human-oocytes/
    Thumbnail for Understanding the maternal age effect in human oocytes - MRC Laboratory of Molecular Biology 15 Dec 2015: Human eggs are frequently aneuploid, meaning they have the wrong number of chromosomes, and this is a major cause of pregnancy loss and Down syndrome.
  3. Human egg defects caused by error-prone spindle assembly - MRC…

    https://www2.mrc-lmb.cam.ac.uk/human-egg-defects-caused-by-error-prone-spindle-assembly/
    Thumbnail for Human egg defects caused by error-prone spindle assembly - MRC Laboratory of Molecular Biology 5 Jun 2015: Miscarriages and genetic disorders, such as Down's syndrome, are often caused by errors when an egg develops from its progenitor cell, the oocyte. Most
  4. Spliceosome U4/U6.U5 tri-snRNP structure revealed by cryo-EM - MRC…

    https://www2.mrc-lmb.cam.ac.uk/spliceosome-u4u6-u5-tri-snrnp-structure-revealed-by-cryo-em/
    Thumbnail for Spliceosome U4/U6.U5 tri-snRNP structure revealed by cryo-EM - MRC Laboratory of Molecular Biology 25 Jun 2015: Genes in eukaryotic organisms are frequently interrupted by non-coding segments called introns. Before the protein can be produced, the entire length of each gene including the introns, is transcribed to produce precursor messenger RNA (pre-mRNA).
  5. Cryo-EM imaging of ribosomes shows the origin of leukaemia - MRC…

    https://www2.mrc-lmb.cam.ac.uk/cryo-em-imaging-of-ribosomes-shows-the-origin-of-leukaemia/
    Thumbnail for Cryo-EM imaging of ribosomes shows the origin of leukaemia - MRC Laboratory of Molecular Biology 19 Oct 2015: Ribosomes, the molecular machines in cells that make proteins, are constructed in a series of discrete steps to create both a large and a small subunit.
  6. Hands-on activities by LMB scientists at the Cambridge Science…

    https://www2.mrc-lmb.cam.ac.uk/hands-on-activities-by-lmb-scientists-at-the-cambridge-science-festival/
    Thumbnail for Hands-on activities by LMB scientists at the Cambridge Science Festival - MRC Laboratory of Molecular Biology 27 Mar 2015: Children queued up excitedly during the Saturday and Sunday daytime sessions to use the microscopes, and the exhibit was also very popular in the new adults-only session on the Saturday
  7. Freeze-thaw cycles turn life’s simple building blocks into functional …

    https://www2.mrc-lmb.cam.ac.uk/freeze-thaw-cycles-turn-lifes-simple-building-blocks-into-functional-macromolecules/
    Thumbnail for Freeze-thaw cycles turn life’s simple building blocks into functional macromolecules - MRC Laboratory of Molecular Biology 5 May 2015: There is compelling evidence that in the distant past, our single-celled ancestors used RNA, a chemical cousin of DNA, for both genetic information
  8. A fundamental protection mechanism against formalin in mammals is…

    https://www2.mrc-lmb.cam.ac.uk/a-fundamental-protection-mechanism-against-formalin-in-mammals-is-revealed/
    Thumbnail for A fundamental protection mechanism against formalin in mammals is revealed - MRC Laboratory of Molecular Biology 25 Sep 2015: This new knowledge has implications for human health: children effected by the cancer and bone marrow failure syndrome Fanconi anaemia are unable to repair the DNA damage caused by formaldehyde.
  9. Structure of ParM reveals how plasmids are maintained in bacteria -…

    https://www2.mrc-lmb.cam.ac.uk/structure-of-parm-reveals-how-plasmids-are-maintained-in-bacteria/
    Thumbnail for Structure of ParM reveals how plasmids are maintained in bacteria - MRC Laboratory of Molecular Biology 27 Apr 2015: The structure of the actin-like protein ParM in different states has been revealed by Tanmay Bharat and Jan Löwe in collaboration with Garib Murshudov
  10. BOLT, a fast and selective way to regulate protein function in live…

    https://www2.mrc-lmb.cam.ac.uk/bolt-a-fast-and-selective-way-to-regulate-protein-function-in-live-cells/
    Thumbnail for BOLT, a fast and selective way to regulate protein function in live cells - MRC Laboratory of Molecular Biology 19 May 2015: Jason Chin’s group from the LMB’s PNAC Division have created a new technique called BOLT that can selectively regulate specific proteins inside cells that could not previously be targeted. ... affected. Genetically engineering an entirely new site
  11. 2015 Francis Crick Lecture to be given by Emmanuelle Charpentier -…

    https://www2.mrc-lmb.cam.ac.uk/2015-francis-crick-lecture-to-be-given-by-emmanuelle-charpentier/
    Thumbnail for 2015 Francis Crick Lecture to be given by Emmanuelle Charpentier - MRC Laboratory of Molecular Biology 21 Sep 2015: She then continued her work in the United States where she held Research Associate positions at the Rockefeller University, New York University Langone Medical Center and the Skirball Institute of Biomolecular

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