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AP2 adaptors for clathrin-mediated endocytosis: These are Cargo…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/index.html26 Sep 2011: Classical adaptors: e.g. the AP2 adaptor complex. appendages). The hinge domains bind to clathrin terminal domains. AP1, AP3 and AP4 adaptors have similar subunit compositions and bind to different cargo and accessory proteins (see Adaptor table 1). -
New intracellular transport system discovered. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-intracellular-transport-system-discovered/10 Oct 2011: Search this website. New intracellular transport system discovered. New intracellular transport system discovered. ... Thus, this new transport system is much more flexible than constricted movement along microtubules.
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New evidence of nuocyte involvement in allergic asthma - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-evidence-of-nuocyte-involvement-in-allergic-asthma/18 Nov 2011: New evidence of nuocyte involvement in allergic asthma. Published on. 18 November, 2011. ... This discovery is an important step in determining whether nuocytes could be a new drug target for asthma treatment.
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Breakthrough in Fanconi Anaemia research. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/breakthrough-in-fanconi-anaemia-research/10 Feb 2011: KJ’s group have discovered a new gene in the mouse FA pathway known as SLX4.
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Propagation of mutant SOD1 misfolding. - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/propagation-of-mutant-sod1-misfolding/23 Feb 2011: Amyotrophic lateral sclerosis (ALS) is caused by the progressive dysfunction of specific nerve cells that control muscle movement. It belongs to a group
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Leon Lagnado Receives Prestigious HFSP Award. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/leon-lagnado-receives-prestigious-hfsp-award/13 May 2011: Leon Lagnado from the LMB’s Neurobiology Division has been awarded a Human Frontiers Science Program (HFSP) Grant. The HFSP is an international funding
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Link Between Ribosome Maturation and Cancer - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/link-between-ribosome-maturation-and-cancer/3 May 2011: They not only define the mechanism underlying a fundamental step in ribosome biogenesis, but also directly identify new approaches to treat the disease.
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Digitization of visual signals in the retina - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/digitization-of-visual-signals-in-the-retina/29 Jun 2011: Using the zebrafish as a model organism, Leon’s group have used new techniques developed in the lab to image the retina of live fish and monitor how the synaptic connections
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LMB scientists reconstruct ‘Nature’s first enzyme’. - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-reconstruct-natures-first-enzyme/8 Apr 2011: The origin of life is one of the great, unsolved mysteries of biology. In a quest to improve understanding of how life might have originally emerged, a
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A small molecule to correct protein folding defects. - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/a-small-molecule-to-correct-protein-folding-defects/10 Mar 2011: to design new drugs that could benefit a broad range of diseases.
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