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Structures of endocytic proteins
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/research/structur/structure.html27 Jun 2007: Gallery of structure for endocytic proteins. There are also links to pages for many endocytic and trafficking proteins. -
Epsin1 tubulation and membrane bending
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/index.html27 Sep 2007: see also News and Views and highlights in Nature Cell Biology, Nature reviews in molecular cell biology, and a mini review in Cell (Cell October 18, 2002: 111 (2):143-146). -
Labparty
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/people/Labparty/labparty.html25 Jun 2007: -
Recruitment of clathrin to membranes by amphiphysin2
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/BARdomains/Amphiphysin_clathrin.html27 Jun 2007: click on image to see a higher resolution version (824 kb) in a new window). -
Prel progr with speakers
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/Prog_PCH_conference.pdf25 Jul 2007: Markus Plomann, Cologne, D Britta Qualmann, Magdeburg, D Ann Siehoff-Icking, Frankfurt, D Richard Stanley, New York, USA. ... Alan Munn, Brisbane, Australia. Mohan Balasubramanian, Singapore. 16:45 Coffee break 17:15 Keynote lecture Pietro de Camilli, -
HARVEY T McMAHON
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/people/CV2006d.html25 Jun 2007: This allowed us to identify new ligands for this domain simply by database trawling. ... Nature 365, 163-166. (see also News and Views). McMahon, H.T. and Nicholls, D.G. -
NSMB0607 RH.indd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/nsmb0607-467.pdf18 Jun 2007: Now, MacKinnon and colleagues have used isothermal titration calorimetry (ITC) and new structural data to investigate how ions are selected by KcsA and the contributions they make in promoting the conductive -
3919Commentary Introduction Kinesin motors use energy supplied by ATP …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/JCScommentary.pdf31 Oct 2007: 1) The tethered, ADP-bound lead head is free to find a new binding site. ... N., Muller,J. and Mandelkow, E. (2000). A new look at the microtubule binding patterns ofdimeric kinesins. -
DOI: 10.1126/science.1136985 , 120 (2007); 316Science et al.Maria C.…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Alonso_Science.pdf6 Apr 2007: The title SCIENCE is a. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. -
doi:10.1016/j.jmb.2007.08.056
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Oliva_FtsZ_JMB_2007.pdf11 Oct 2007: We propose a new model in whichlateral interactions help determine the curvature of protofilaments. ... Similarly, our new pair of AaFtsZ:GDPand AaFtsZ:8-morpholino-GTP show even smallerdifferences (rmsd 0.2 Å). -
ANALYSIS Integrating molecular and network biologyto decode…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007.pdf22 Aug 2007: c, Changing hubs: clathrin is recruited andpolymerization stabilizes the forming vesicle, displacing the AP2recruitment hub and becoming the new organizing hub. ... Clustered hubs’ are a new sub-type of hubs not previously described (Supplementary -
PowerPoint Presentation
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/ITC/Calorimetry%20Tutorial.ppt_files/Calorimetry%20Tutorial.ppt.ppt4 Dec 2007: H must be large and negative (gain new bonds). S must be large and positive (gain more entropy). -
Supplementary Text & Figs
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007Sup.pdf22 Aug 2007: be appropriately interpreted. Part 3: Clustered-hubs. Clustered-hubs are a new subtype of hubs not previously described. ... new subtype of hubs that we find in CME. These can be composed of proteins with. -
DOI: 10.1126/science.1135394 , 239 (2007); 317Science et al.Nabil…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17626883.pdf8 Dec 2007: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. -
PowerPoint Presentation
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Interactomes/NetworkWebTalk_files/NetworkWebTalk.html.ppt21 Aug 2007: AP2 loses its position as a hub. Clathrin is the new. ... AP2. E. Energy is used to re-prime the system for a new start. -
Structural and Membrane Binding Analysis of the PhoxHomology Domain…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17581820.pdf8 Dec 2007: Fatty acid-free bovine serum albumin was from Bayer(Kankakee, IL). Restriction endonucleases and other enzymesfor molecular biology were from New England Biolabs (Beverly,MA). ... Bem1p-PX, but alsothe mechanism by which this PX domain interacts -
Structural insight into the ESCRT-I/-II link and itsrole in ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17215868.pdf14 Jun 2007: We also show that a new component of. ESCRT-I, Mvb12 (YGR206W), engages ESCRT-I directly. ... ESCRT-I binds directly to a new subunit, Mvb12,. forming a stable 1:1:1:1 heterotetrameric complex. -
LETTERS Structural basis for selective recognition of ESCRT-IIIby the …
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17928861.pdf8 Dec 2007: 2Department of Molecular Biology and Genetics and Institute for Cell andMolecular Biology, Biotechnology Building, Cornell University, Ithaca, New York 14853, USA. -
Structural analysis of the ParR/parC plasmidpartition complex Jakob…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MollerJensen_ParR_EMMBO_2007.pdf4 Oct 2007: model of ParM-mediated plasmid partition that takes the new. ParR structure into account. ... T, Warren GL (1998) Crystallography &NMR system: a new software suite for macromolecular structuredetermination. -
Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: trates a capacity for small proteins to target the ‘undruggable’. protein interaction surface, presenting a new spectrum of. ... Springer: New York, USA. CCP4 (1994) The CCP4 suite: programs for protein crystallography.Acta Crystallogr D 50: 760–763 -
doi:10.1016/j.str.2007.05.002
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/FCH02F-BARHenne07.pdf2 Jun 2007: Structure. Article. Please cite this article in press as: Henne et al., Structure and Analysis of FCHo2 F-BAR Domain: A Dimerizing and Membrane RecruitmentModule that Effects Membrane Curvature, Structure (2007), doi:10.1016/j.str.2007.05.002. -
The structural basis of novel endosome anchoringactivity of KIF16B ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17641687.pdf23 Jul 2007: andImmunology, Weill Medical College of Cornell University, New York,NY, USA. -
nrm2162.indd
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17450176.pdf14 Jun 2007: Several previously unsuspected key links between multiple ESCRT subunits, phospholipids and ubiquitin have now been elucidated, which, together with the detailed morphological analyses of ESCRT-depletion phenotypes, provide new insights into -
tra_578 1..18
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Burtey%20IVF%20Traffic%2007.pdf15 May 2007: 1Institut Cochin, Université Paris Descartes, CNRS(UMR 8104), Paris, France2INSERM, U567, 75014 Paris, France3MRC Laboratory of Molecular Biology, Cambridge,CB2 2QH, UK4The Laboratory of Cellular Biophysics, The RockefellerUniversity, New York, NY -
Molecular Biology of the CellVol. 18, 3681–3691, September 2007 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/48_Rutkowski_DT_MBC_2007.pdf15 Aug 2007: The unfolded protein re-sponse (UPR) consists principally of two broad strategies fordealing with ER stress: increased clearance of misfoldedproteins from the ER lumen and reduction of new proteininflux into the ... This phosphor-ylation leads to rapid -
CELL AND MOLECULAR PHYSIOLOGY Intracellular Ca2+ release via the ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/44_Ong_HL_Pflug_Arch_2007.pdf15 Feb 2007: Biochim Biophys Acta 1711:33–40. 7. Haigh NG, Johnson AE (2002) A new role for BiP: closing theaqueous translocon pore during protein integration into the ERmembrane. -
"Rational Design and Evaluation of FRET Experiments to Measure…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/40_Snapp_EL_Curr_Prot_2006.pdf11 May 2007: UNIT 17.9Rational Design and Evaluation of FRETExperiments to Measure ProteinProximities in Cells. Defining the repertoire of interactions thata particular protein can undergo is crucialfor understanding its function and regulation.Characterizing
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