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Per Bullough - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-per-bullough/30 Mar 2021: Search this website. Per Bullough. Per Bullough was a Ph.D. student in the Structural Studies Division at LMB from 1985-1989 developing new methods of low-dose imaging of biological -
Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/geoffrey-grigg/21 May 2021: Geoffrey Grigg (1926 - 2008) Geoffrey Grigg was an Australian visitor to the LMB with Fred Sanger in 1972-1974 and Greg Winter in 1988, and often visited -
2021 Max Perutz Lecture to be given by David Baker - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/2021-max-perutz-lecture-to-be-given-by-david-baker/20 Apr 2021: This milestone accomplishment highlights the potential of protein engineering to produce new materials to reform and regulate biological systems. ... Our goal is to design a new generation of proteins that address current-day problems not faced during -
“The LMB provides an unsurpassed environment for both new ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=1885218 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics. -
Tail of SARS-CoV-2 Spike protein is optimised to reach the cell…
https://www2.mrc-lmb.cam.ac.uk/tail-of-sars-cov-2-spike-protein-is-optimised-to-reach-the-cell-surface-causing-infection-to-spread-to-neighbouring-cells/10 Sep 2021: Most of these new Spike proteins accumulate in an intracellular structure named Golgi which assembles new viruses. ... the Golgi apparatus, then hold it there whilst new viruses are made. -
Early transcriptional patterning of a forming tissue is essential to…
https://www2.mrc-lmb.cam.ac.uk/early-transcriptional-patterning-of-a-forming-tissue-is-essential-to-morphogenesis-of-a-tubular-organ/8 Nov 2021: Time-lapse quantitative study of developing salivary glands in Drosophila embryos, conducted by Katja Röper’s group, reveals the key control factors behind cells’ behavioural transitions that are essential for correct organ formation. -
Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C, -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x75.html24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h. -
‘Making Visible’ poetic illuminations move to the LMB - MRC…
https://www2.mrc-lmb.cam.ac.uk/making-visible-poetic-illuminations-move-to-the-lmb/10 Dec 2021: Making Visible’ allowed colleagues to connect with each other and explore their scientific work in new, creative ways. -
Dan Brown (1923 - 2010) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dan-brown-1923-2010/30 Mar 2021: Dan Brown 1923 - 2012 It is with great sadness that we report that Dan Brown, who had been battling cancer for some time, died on Tuesday April 24, 2012, -
How the fate of immune cell precursors is decided - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/how-the-fate-of-immune-cell-precursors-is-decided/11 Jan 2021: 11 January, 2021. Discovery of a new checkpoint that controls the development of innate immune cells with a key role in parasite defence and allergy. ... This led to their proposal of a new transcription factor network to explain how RORα regulates -
Coot Scripting Interface: cc-interface.hh Source File
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/cc-interface_8hh_source.html24 Aug 2021: 474 // return the status and vector of chain-ids of the new chain ids. ... 1312 mmdb::Manager new_molecule_by_symmetry_matrix_from_molecule(mmdb::Manager mol,. -
The Coot User Manual
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html1 Mar 2021: The Coot User Manual -
Behind the scenes: Paul Hart and the development of IT at the LMB -…
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-paul-hart-and-the-development-of-it-at-the-lmb/20 Dec 2021: The biggest challenge. Several year later the new building project came my way. ... I’d worked on a couple of new building projects, but never as a lead. -
Dinolite Instructions
https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions_detailed_2021.22_LJM.doc18 Oct 2021: If no new image appears, move the mouse until it does (you may see the last image taken otherwise). ... 5. To take a new image, place your mouse over anything other than an existing thumbnail. -
Coot Scripting Interface: c-interface.h Source File
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html24 Aug 2021: 447. 457 int add_ligand_delete_residue_copy_molecule(int imol_ligand_new,. ... If it doesn't then we /. 1527 / go down a (new 20060920) different path. /. -
KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=2135527 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/. -
KENDREW LECTURE(Part 2) Wednesday 13th October @ 4.00 pmDetails ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=2135627 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/. -
Setting the stage: development of sample holders for electron ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=2129521 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium. -
Behind the scenes: Maria Daly and the flow cytometry facility - MRC…
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-maria-daly-and-the-flow-cytometry-facility/31 Mar 2021: Behind the scenes: Maria Daly and the flow cytometry facility Maria Daly is manager of the LMB’s Flow Cytometry Facility, which provides LMB scientists -
Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure. -
BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x64.html24 Aug 2021: default_new_atoms_b_factor() : c-interface.h. -
Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/30 Mar 2021: the centre of the new field of molecular biology. -
Mark Bretscher - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mark-bretscher/30 Mar 2021: Mark S. Bretscher Mark Bretscher studied Chemistry at the University of Cambridge, before joining the MRC Laboratory of Molecular biology as a research -
Heart cell clocks help coordinate daily cardiac function - MRC…
https://www2.mrc-lmb.cam.ac.uk/heart-cell-clocks-help-coordinate-daily-cardiac-function/21 Oct 2021: Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through -
Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC…
https://www2.mrc-lmb.cam.ac.uk/francis-crick-lecture-to-be-given-by-michel-c-nussenzweig/8 Nov 2021: Michel received a B.C. summa cum laude from New York University in 1976, a PhD degree with Ralph Steinman from Rockefeller University in 1981 and an M.D. ... degree from New York University Medical School in 1982. Following this he completed a medical -
Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/wasi-faruqi-awarded-mbe-in-queens-birthday-honours/14 Jun 2021: Wasi (Abdul Raffey) Faruqi, from the LMB’s Structural Studies Division, has been made a MBE in the Queen’s 2021 Birthday Honours List -
Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC…
https://www2.mrc-lmb.cam.ac.uk/michel-goedert-awarded-the-2021-hartwig-piepenbrock-dzne-prize/15 Oct 2021: Hopefully, the new knowledge will lead to the development of safe and effective mechanism-based therapies for common neurodegenerative diseases.”. -
Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/max-perutz-1914-2002/30 Mar 2021: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures -
John Finch Collection - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/john-finch-collection/31 Mar 2021: He came to the new LMB in 1962 with the Birkbeck group, which was now led by Aaron Klug after Rosalind’s death in 1958. -
César Milstein Lecture to be given by Hans Clevers - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-hans-clevers/23 Nov 2021: Hans Clevers from the Hubrecht Institute will deliver the 2021 César Milstein Lecture on how organoids can be used to model human diseases. -
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf29 Aug 2021: Q5 High-Fidelity 2X Master Mix (New England Biolabs,. Ipswich, MA, USA) as per manufacturer’s instructions. -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x75.html24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h. -
Madeline Lancaster on serendipity and adventure in science - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-on-serendipity-and-adventure-in-science/22 Sep 2021: Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids – -
A colourful welcome back for the LMB Arts and Crafts Show - MRC…
https://www2.mrc-lmb.cam.ac.uk/a-colourful-welcome-back-for-the-lmb-arts-and-crafts-show/5 Aug 2021: The LMB Arts and Crafts Show: showcasing the creative talents of the LMB -
Dr. George Pieczenik - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dr-george-pieczenik/30 Mar 2021: Dr. George Pieczenik Dr. George Pieczenik worked in the MRC Laboratory of Molecular Biology at intervals during the years 1972-1987. He was an early -
Bretscher Archive - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/manuscripts-correspondence/bretscher-archive/28 Sep 2021: Search this website. Bretscher Archive. The MRC Unit moved out of the Cavendish Laboratory to the new LMB site in early 1962. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html14 Apr 2021: Henderson, R. IUCrJ 3, 3-7 (2016). CryoEM at IUCrJ: a new era. ... Caspar, D.L.D. Nature, News & Views 345, 666-667 (1990). Bacteriorhodopsin - at last! -
16262551036386 1..32
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received: -
A unified evolutionary origin for the ubiquitous protein transporters …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/BMC_Biology_2021.pdf15 Dec 2021: s hydrophilic groove and its capping hydrophobicresidue are homologous to key residues in SecY’s hydro-philic funnels and its pore ring, respectively.In light of this new correspondence, we -
The mechanisms of integral membrane protein biogenesis
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf22 Sep 2021: These areas have recently seen the discovery of new machinery, mechanis-tic insights from structural and bioinformatics analysis, and the emergence of new concepts. ... Here we consider comparatively recent new insights into the basis of SRP substrate -
Science Journals — AAAS
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf26 Aug 2021: The PSMC5 construct for in vitro translation in the PURE system was similar to that in pSP64, but in the T7-based PURExpress plasmid from New England Biolabs. ... The resin was then. 6. washed 5 times in PSB, and transferred to a new tube. -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x64.html24 Aug 2021: default_new_atoms_b_factor() : c-interface.h. -
Madeline Lancaster awarded the 2021 ISSCR Dr Susan Lim Award - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-awarded-the-2021-isscr-dr-susan-lim-award/26 Jan 2021: They found that ChP cells express ACE2, the receptor needed for SARS-CoV-2 entry, on their surface and that the virus was able to infect and produce new virus inside ... The development of cerebral organoids has significant implications not only for -
Hans Boye - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-hans-boye/30 Mar 2021: Hans Boye Hans Boye was a research student with Francis Crick from October 1961-1964, and was Crick's second and last student. His area of research was on -
Bernard Jacrot - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/bernard-jacrot/30 Mar 2021: With Maier-Leibnitz, they recruited the young German and French scientists and engineers who designed and built a new generation of instruments (some of which were politely considered to be ‘odd’ ... He established a group in structural virology that -
Chris Tate and Sjors Scheres elected Fellows of Royal Society - MRC…
https://www2.mrc-lmb.cam.ac.uk/chris-tate-and-sjors-scheres-elected-fellows-of-royal-society/6 May 2021: Each year the Fellows of the Royal Society elect up to 52 new Fellows, and up to 10 new Foreign Members. ... Our new Fellows and Foreign Members are all at the forefronts of their fields from molecular genetics and cancer research to tropical open -
Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/herbert-freddie-gutfreund/18 Nov 2021: Herbert ‘Freddie’ Gutfreund Freddie Gutfreund was born in Vienna on 21st October 1921. In 1938, aged 17, he arrived in England as a refugee, initially to -
Furin protease is not essential for SARS-CoV-2 infection - MRC…
https://www2.mrc-lmb.cam.ac.uk/furin-protease-is-not-essential-for-sars-cov-2-infection/29 Jan 2021: This process might play a role in virus spread between cells even in the absence of production of new virus particles. ... The emergence of new SARS-CoV-2 variants is a real concern as they can threaten the effectiveness of the approved SARS-CoV-2
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