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23 Jul 2024: Carazo, M. Mann & W. Baumeister (2009) "New insights into the molecular architecture of the 26S proteasome". ... S.H.W. Scheres & P. Gros (2001) "Conditional optimization: a new formalism for protein structure refinement".

25 Jan 2024: Cell Biology Division The Division aims to understand the biological organisation of cells and organisms, and the molecular mechanisms underlying their

6 Jun 2024: We also explore new insights into protein folding and evolution, suggested by non-trivial relationships discovered during the classification of new protein families in SCOP and SCOP2. ... Structural classification of proteins and structural genomics: new

15 Feb 2024: The LMB is saddened to learn of the death of Samantha Skehel, who worked as Grants Manager in the Finance Team and later Technical Officer in the Lab Services and Purchasing Team. Since 2015, she has been based at the Isaac Newton Institute for

19 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-and-events/information-for-journalists/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes

21 May 2024: Greg Jefferis’ group in the LMB’s Neurobiology Division, in collaboration with scientists at the Janelia Research Campus, have predicted the sign of each synapsis in the fruit fly brain.

8 Jul 2024: Useful Links   UKRI use of animals in research The National Centre for the Replacement, Refinement and Reduction of Animals in Research Understanding

23 Feb 2024: We work on developing new instruments and methods for imaging biological molecules, (DNA, RNA and proteins), at atomic resolution. ... Using this new technology, we study the detailed mechanisms of biomolecules to understand how they function.

23 Feb 2024: In another line of research, we use experimental cryo-EM together with our own image processing developments to discover new protein structures. ... RELION-3: new tools for automated high-resolution cryo-EM structure determination.

26 Mar 2024: Delineating the molecular mechanisms that impart daily rhythms to our biology is therefore important for understanding human health and may provide new insights into the prevention and treatment of many diseases.

1 Jul 2024: Synthetic biology enables us to control certain genetic programs and introduce novel phenotypes in model bacteria such as E. coli, though as a field we

5 Jan 2024: preparation. The Passmore lab developed new gold and graphene specimen supports that improve cryo-EM images.

31 Jan 2024: Published on. 31 January, 2024. Jason Chin spoke to BBC’s Roland Pease about his group’s new EcORep orthogonal replication system that enables rapid protein evolution in E.coli and ... how it could help create new substances to be used in medicine &

17 Jan 2024: recollected that Kiyoshi had told her that “It’s never too late to try and learn something new”.

16 May 2024: Each year the Royal Society recognizes excellence in science and technology through its medals, awards and prize lectures and the election of new Fellows.

23 Feb 2024: Our broad goal is to understand how smell turns into behaviour in the fruit fly brain. We currently use a combination of genetic labelling and

23 Feb 2024: The machines that comprise this proteostasis network include the ribosome, which synthesizes new proteins, chaperones that help new proteins fold, and degradation factors that eliminate incorrect or damaged proteins. ... We expect that our results will

15 May 2024: The compartments of the secretory and endocytic pathways are connected by membrane-bound carriers that bud from, and then fuse with, specific organelles.

29 Apr 2024: 2023: Finally, divisome core complex resolved. Cell division in the vast majority of bacteria depends on the synthesis of new cell wall peptidoglycan and is catalysed by the divisome.

21 May 2024: Academy of Medical Sciences The Academy of Medical Sciences is an independent body in the UK that represents the diverse spectrum of medical science –