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Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure. -
BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in -
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf29 Aug 2021: Q5 High-Fidelity 2X Master Mix (New England Biolabs,. Ipswich, MA, USA) as per manufacturer’s instructions. -
A unified evolutionary origin for the ubiquitous protein transporters …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/BMC_Biology_2021.pdf15 Dec 2021: s hydrophilic groove and its capping hydrophobicresidue are homologous to key residues in SecY’s hydro-philic funnels and its pore ring, respectively.In light of this new correspondence, we -
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https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received: -
The mechanisms of integral membrane protein biogenesis
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf22 Sep 2021: These areas have recently seen the discovery of new machinery, mechanis-tic insights from structural and bioinformatics analysis, and the emergence of new concepts. ... Here we consider comparatively recent new insights into the basis of SRP substrate -
Science Journals — AAAS
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf26 Aug 2021: The PSMC5 construct for in vitro translation in the PURE system was similar to that in pSP64, but in the T7-based PURExpress plasmid from New England Biolabs. ... The resin was then. 6. washed 5 times in PSB, and transferred to a new tube.
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