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  2. PPL number: | Granted: 24 Sep 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_physical_cues_in_nervous_system_function_in_wild_type_and_transgenic_anima_redacted.pdf
    19 Aug 2021: The long-term goal of this research is to discover new mechanisms controlling the growth of nerve cells.
  3. PPL number: | Granted: 14 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_transposable_elements_in_cichlid_fish_development_and_evolution_nts_redacted.pdf
    13 Sep 2021: Our investigations and the data generated are expected to lead to new collaborations with other researchers. ... We will incorporate new recommendations on animal welfare, as soon as possible after their publication.
  4. PPL number: | Granted: 04 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_and_treatment_of_pulmonary_vascular_diseases_redacted.pdf
    18 Jun 2021: We aim to develop new approaches to treatment that target the pathways identified from human genetic studies. ... We will disseminate new knowledge and findings by publishing our results in internationally recognised scientific journals.
  5. PPL number: | Granted: 06 Jul 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_the_immune_system_in_cardiovascular_disease_nts_expires2026_redacted.pdf
    13 Sep 2021: However, our understanding of how this happens is still limited, and this has prevented scientists from finding new effective treatments. ... Our results will therefore benefit the scientific community through the provision of important new knowledge
  6. PPL number: | Granted: 22 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/impact_of_sensory_and_electrical_activity_on_neuronal_function_nts_redacted.pdf
    13 Sep 2021: Chiefly, outputs will include generation of new knowledge, which will be timely and freely disseminated as publications in open-access journals, full datasets, and conference presentations. ... Before behavioural testing, mice will be acclimatised to the
  7. PPL number: | Granted: 02 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf
    18 Jun 2021: We expect to test new compounds that inhibit alpha-synuclein aggregation into clumps and spreading to delay the development of pathology. ... Several collaborations are in place and will be developed to obtain new tools to further the understanding of
  8. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_integrated_stress_response_in_respiratory_disease_nts_redacted.pdf
    13 Sep 2021: All new information will be presented at scientific conferences and published as peer-reviewed research articles. ... When repeated or prolonged interventions are required, animals will be acclimitised to new environments (e.g.
  9. PPL number: | Granted: 24 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_genetically_altered_animals_for_regenerative_neuroimmunology_research_redacted_0.pdf
    18 Jun 2021: We are using new-born mice to collect cells to grow and keep in a dish to do experiments. ... provide additional sources of new recommendations and advances in animal techniques and clinically applicable models.
  10. PPL number: | Granted: 04 Feb 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/tuberculosis_pathogenesis_treatment_in_zebrafish_and_medaka_nts_redacted.pdf
    19 Aug 2021: Animals from these new lines will be used to generate eggs by natural spawning. ... In the case of new chemicals, pilot experiments will be used to test chemical toxicity.
  11. PPL number: | Granted: 12 Feb 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/promoting_proliferation_in_non-regenerative_tissues_nts_expires2026_redacted.pdf
    13 Sep 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.

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