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  2. Breakthrough in structural biology reveals mitochondrial ribosome…

    https://www2.mrc-lmb.cam.ac.uk/breakthrough-in-structural-biology-reveals-mitochondrial-ribosome-structure/
    Thumbnail for Breakthrough in structural biology reveals mitochondrial ribosome structure - MRC Laboratory of Molecular Biology 28 Mar 2014: new proteins into the EM maps and optimise their fit.
  3. The mother’s role in protecting the fetal genome from aldehyde damage …

    https://www2.mrc-lmb.cam.ac.uk/the-mothers-role-in-protecting-the-fetal-genome-from-aldehyde-damage-is-revealed/
    Thumbnail for The mother’s role in protecting the fetal genome from aldehyde damage is revealed. - MRC Laboratory of Molecular Biology 22 Aug 2014: The fact that the mother can protect the genomic integrity of the developing fetus is a new and significant finding.
  4. 1 Clear StrategyTM Screen I MD1-14 A 6 × ...

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB10.pdf
    2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to
  5. ProSMART Tutorial - Part 2a

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/prosmart_tutorial/files/part_2a.html
    14 Apr 2014: Firstly, follow these steps:. Start a new session - close PyMOL, then re-open it. ... Start a new ProSMART CCP4i job, and load 1ryx.pdb and 1ryx_prosmart_refine.pdb as the target and reference structures, respectively.
  6. PowerPoint Presentation

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/Ligand-meeting-July-9.pptx
    9 Jul 2014: Second option, two candidates. 12. Building the new Dictionary Clustering the data from COD. ... 15. Generator of molecule geometries using the new Dictionary. A “greedy” global optimization scheme.
  7. ProSMART Tutorial - Part 2b

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/prosmart_tutorial/files/part_2b.html
    14 Apr 2014: Firstly, follow these steps:. Start a new session - close CCP4mg, then re-open it. ... Firstly follow these steps:. Start a new session - close CCP4mg, then re-open it.
  8. ProSMART Tutorial - Part 1

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/prosmart_tutorial/files/part_1.html
    14 Apr 2014: For our next round of refinement:. Open a new REFMAC5 job in the CCP4i GUI. ... Provide the original 1ryx.mtz structure factor file in the "MTZ in" fields, and provide the new modified model in the "PDB in" field.
  9. JCSG+ Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB11.pdf
    2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to
  10. PowerPoint Presentation

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2014/media/Food_For_Thought.pptx
    30 Apr 2014: Amino acids to make new proteins and neurotransmitters. Vitamins to carry out essential processes, especially B vitamins, and to act as antioxidants (E & C).
  11. refmac keywords

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/refmac_keywords.html
    6 Oct 2014: 2) Put zero inside the sphere centred at current atom with new radius. ... n4 - weighting options. New instructions (a little bit more flexible and useful for complex molecules):.
  12. Madeline A. Lancaster Culturing feeder-free human ES cells Modified…

    https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/download/Culturing-feeder-free-human-ES-cells.docx
    21 Mar 2014: 2. Prepare new Matrigel plates as above or warm pre-prepared Matrigel coated dishes in the incubator. ... Add additional media needed. c. Generally minimize pipetting! 8. Transfer 0.5 ml cells per new well and place back in the incubator, being careful
  13. 7 NOVEMBER 2014 • VOL 346 ISSUE 6210 7 ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/90_Shao_S_Science_2014.pdf
    8 Nov 2014: that benefit from bacteria. Validation of. this promising new cell culture model for. ... The power of quantitative proteomics may. well shift how new biological pathways are.
  14. Onl_Er_embj_201488930_GA 1..3

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/86_Hegde_RS_EMBO_2014.pdf
    10 Jun 2014: The new studies focus on tail-anchored. (TA) membrane proteins, defined topologi-.
  15. Word macros that will translate a highlighted area of ...

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/resources/computer/word_macros/TranslateIncNucleotide2.docx
    4 Feb 2014: Selection.Font.Name = "Courier New". Selection.Font.Size = 8. Selection.TypeText (output).
  16. MinCD cell division proteins form alternating copolymeric cytomotive…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ncomms6341.pdf
    6 Dec 2014: analyses, we show that MinD activates MinC by forming a new class of alternating. ... We combined our new crystalstructure with the EcMinD dimer structure, revealing twointeresting features (Fig.
  17. Madeline A. Lancaster Culturing feeder-dependent human iPS/ES cells…

    https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/download/Culturing-human-ES-and-iPS-cells.docx
    21 Mar 2014: Add 1 ml hES media to well. 10. Resuspend hiPSC pellet in 1 ml hES media per new well of 6-well plate and triturate gently with P1000 tip to get ... 7. Wash the old well with another 1 ml hES media and transfer to new well.
  18. pone.0107211 1..10

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/leoa2014.pdf
    3 Sep 2014: LeoA, B and C from Enterotoxigenic Escherichia coli(ETEC) Are Bacterial DynaminsKatharine A. Michie1.¤a, Anders Boysen2., Harry H. Low1.¤b, Jakob Møller-Jensen2, Jan Löwe1. 1 MRC Laboratory of Molecular Biology, Structural Studies Division,
  19. Tutorial 4: Statistical Theory;Why is the Gaussian Distribution so ...

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-4-statistical-theory/?wpdmdl=18816&refresh=668d521cbbbac1720537628
    20 Mar 2014: 7. Use a ‘for loop’ to iteratively recreate a new random Bin(100, 0.4) sample of100 observations and overplot the corresponding empirical density functionsonto the plot of the Normal density
  20. INVITED REVIEW Mechanosensory molecules and circuits in C. elegans ...

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-2.pdf
    10 Dec 2014: INVITED REVIEW. Mechanosensory molecules and circuits in C. elegans. William R. Schafer. Received: 3 June 2014 /Revised: 30 June 2014 /Accepted: 2 July 2014 /Published online: 23 July 2014# The Author(s) 2014. This article is published with open
  21. DOI: 10.1126/science.1256917, 963 (2014);346 Science et al.Thomas G.…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Science-2014-Gligoris-963-7.pdf
    21 Nov 2014: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... Cross-linking cohesin containing cysteinesat all three interfaces generated a new formform (Ci) whose electrophoretic mobility
  22. elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf
    6 Jun 2014: The elongasome ensures that new glycan strands cross-linked by short peptides are inserted along the peptidoglycan scaffold during cell elongation (den Blaauwen et al., 2008; Goffin and Ghuysen, 1998; Matsuhashi
  23. Tutorial 4: Statistical Theory;Why is the Gaussian Distribution so ...

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/statistical_theory_why_is_the_gaussian_distribution_so_popular.pdf
    20 Mar 2014: 7. Use a ‘for loop’ to iteratively recreate a new random Bin(100, 0.4) sample of100 observations and overplot the corresponding empirical density functionsonto the plot of the Normal density
  24. elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf
    31 Dec 2014: eLife digest Cell division is the process by which new cells are made. ... In the long run, intricate knowledge of how a bacterial cell divides might enable the design of new classes of antibiotics targeting the molecular machinery involved.DOI:
  25. Use and misuse of statistics

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture1_Intro.pptx
    23 Feb 2014: 8. Knowledge. New system. Model. Experiment. Estimate. Verify. Predict. A simple diagram of scientific research: When you know the system. ... Then you use observations and build some sort of model and then check it against the (new) data.
  26. Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/introduction_to_r.pdf
    6 Mar 2014: 2. Use x, along with mathematical operators, to create a new vector y equivalentto: c(1,4,9). ... Similarly to how sub-vectors may be extracted from vectors, sub-vectors canalso be assigned new values.
  27. Tutorial 2: Descriptive Statisticsand Exploratory Data Analysis Rob…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-2-descriptive-statistics/?wpdmdl=18814&refresh=668d521c0efa11720537628
    6 Mar 2014: hist(rnorm(1000)). would result in histograms being created using new vectors of artificially-generatedrandom Normal data. ... What is the dif-ference between the new and old Spearman correlation coefficients?
  28. Basic principles of probability theory

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture6_linear.ppt
    31 Mar 2014: If observations change (for example few outliers are removed or new observations become available) then AIC should be applied for all models again. ... We can expect that in future when we will have new observations this function will give smallest
  29. Basic principles of probability theory

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-6-linear-regression/?wpdmdl=18812&refresh=668d521d343ac1720537629
    31 Mar 2014: If observations change (for example few outliers are removed or new observations become available) then AIC should be applied for all models again. ... We can expect that in future when we will have new observations this function will give smallest
  30. Tutorial 6: Linear RegressionRob Nicholls –…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/linear_regression.pdf
    31 Mar 2014: In order to do this, we need tocreate a new variable before attempting to regress y against x1 and x22, e.g.:.
  31. Tutorial 6: Linear RegressionRob Nicholls –…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-6-linear-regression/?wpdmdl=18818&refresh=668d521d49ad31720537629
    31 Mar 2014: In order to do this, we need tocreate a new variable before attempting to regress y against x1 and x22, e.g.:.
  32. Tutorial 2: Descriptive Statisticsand Exploratory Data Analysis Rob…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/descriptive_statistics_and_exploratory_data_analysis.pdf
    6 Mar 2014: hist(rnorm(1000)). would result in histograms being created using new vectors of artificially-generatedrandom Normal data. ... What is the dif-ference between the new and old Spearman correlation coefficients?
  33. Use and misuse of statistics

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-1-introduction-use-and-misuse-of-statistics/?wpdmdl=18805&refresh=668d521bac9ab1720537627
    23 Feb 2014: 8. Knowledge. New system. Model. Experiment. Estimate. Verify. Predict. A simple diagram of scientific research: When you know the system. ... Then you use observations and build some sort of model and then check it against the (new) data.
  34. Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-introduction-to-r-rob-nicholls-nichollsmrc-lmb-cam-ac-uk-mrclmbstatistics-course-2014/?wpdmdl=18813&refresh=668d521bc27cf1720537627
    6 Mar 2014: 2. Use x, along with mathematical operators, to create a new vector y equivalentto: c(1,4,9). ... Similarly to how sub-vectors may be extracted from vectors, sub-vectors canalso be assigned new values.

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