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Cambridge beats old rival in Workplace Cycle Challenge - MRC…
https://www2.mrc-lmb.cam.ac.uk/cambridge-beats-old-rival-in-workplace-cycle-challenge/14 Jul 2010: Both cities ran Workplace Cycle Challenges between 7 and 27 June but it was Cambridge that managed to persuade more people onto their bikes, with 132 new cyclists compared to
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Section of access road to be named after DNA scientist - MRC…
https://www2.mrc-lmb.cam.ac.uk/section-of-access-road-to-be-named-after-dna-scientist/9 Jul 2010: 9 July, 2010. “A road leading to a new £200 million Cambridge laboratory is to be named after legendary scientist Francis Crick. ... This article is no longer available from the source website: Cambridge News 9 July 2010.
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Aaron Klug: Up among the large biomolecular molecules - MRC…
https://www2.mrc-lmb.cam.ac.uk/aaron-klug-up-among-the-large-biomolecular-molecules/10 Dec 2010: In the Prefatory Article for this year’s Annual Review of Biochemistry, Sir Aaron Klug describes his extraordinary life and scientific achievements. The
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The microscope that can see a flea's beating heart - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-microscope-that-can-see-a-fleas-beating-heart/25 Jun 2010: “The best of the UK's cutting-edge science, engineering and technology are on display at London's Southbank Centre as the Royal Society opens its
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Brain cartography: the fly mating dance neurons mapped - MRC…
https://www2.mrc-lmb.cam.ac.uk/brain-cartography-the-fly-mating-dance-neurons-mapped/29 Sep 2010: “How the bundles of neurons in the brain controls behaviour remains an ongoing mystery. Researchers from the Institute of Molecular Pathology (IMP), in
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LMB scientist honoured as inspirational young female talent - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientist-honoured-as-inspirational-young-female-talent/16 Feb 2010: LMB scientist Dr Sarah Teichmann has received a ‘2009 Women of the Future’ award as ‘Science and Technology Woman of the Future’ for her major
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Scientists ‘give botox a facelift’ to improve its use in medicine -…
https://www2.mrc-lmb.cam.ac.uk/scientists-give-botox-a-facelift-to-improve-its-use-in-medicine/14 Oct 2010: This new approach will enable researchers to improve its use as a treatment for diseases such as Parkinson’s, cerebral palsy and chronic migraine. ... This new clipping method produced a refined botox-like molecule, practical for clinical use but
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David Komander to receive Young Investigator Programme EMBO Award -…
https://www2.mrc-lmb.cam.ac.uk/david-komander-to-receive-young-investigator-programme-embo-award/29 Nov 2010: EMBO New Members Press Release. Primary Sidebar. Search. Search this website.
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Roger Williams elected as Academy of Medical Sciences Fellow - MRC…
https://www2.mrc-lmb.cam.ac.uk/roger-williams-elected-as-academy-of-medical-sciences-fellow/10 May 2010: Dr Roger Williams, group leader in LMB’s PNAC Division, has been elected as a Fellow of the Academy of Medical Sciences. The Academy promotes the
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BBC Look East 'Topping out' of MRC Laboratory in Cambridge -…
https://www2.mrc-lmb.cam.ac.uk/bbc-look-east-topping-out-of-mrc-laboratory-in-cambridge/10 Sep 2010: “The coverage of the 'Topping Out' ceremony shown on BBC Look East can be seen by clicking on the more link.” More …
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Molecular basis for membrane remodelling and organization
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/JMConference/speakerprofiles.html21 Nov 2010: Membrane curvature and COP coated vesicle budding. ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions. Ambroggio E, Sorre B, Bassereau P, Goud B, Manneville JB, Antonny B. EMBO J. 2009, Nov19. -
LMB scientists redefine how our immune system responds to viruses -…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-redefine-how-our-immune-system-responds-to-viruses/2 Nov 2010: The research team has further shown that increasing the amount of TRIM21 protein in cells makes this process even more effective, suggesting new ways of making better antiviral drugs. ... for developing new antiviral drugs.”.
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Body clock pills 'could cure jet lag and manic depression' -…
https://www2.mrc-lmb.cam.ac.uk/body-clock-pills-could-cure-jet-lag-and-manic-depression/24 Aug 2010: “A team of British and American scientists have found a drug which can slow down, kick start and reset the body clocks of mice. It does this by
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Sexual attraction could be due to the wiring of the brain - MRC…
https://www2.mrc-lmb.cam.ac.uk/sexual-attraction-could-be-due-to-the-wiring-of-the-brain/6 Oct 2010: The new study investigated how neurons expressing fruitless are wired up.
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Brad Amos elected Honorary Fellow of the Royal Microscopical Society…
https://www2.mrc-lmb.cam.ac.uk/brad-amos-elected-honorary-fellow-of-the-royal-microscopical-society/23 Aug 2010: He is also developing confocal and multiphoton laser scanning microscopes incorporating the new lens.
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Cancer-causing viruses exploit genetic achilles heel, finds study -…
https://www2.mrc-lmb.cam.ac.uk/cancer-causing-viruses-exploit-genetic-achilles-heel-finds-study/27 Apr 2010: “Scientists say some viruses can turn cells into 'viral hotels' by exploiting tiny molecules derived from human DNA. The UK study found that some
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Grant winners - Biotechnology and Biological Sciences Research…
https://www2.mrc-lmb.cam.ac.uk/grant-winners-biotechnology-and-biological-sciences-research-council/23 Jun 2010: “Sixteen transnational projects have received EUR24 million (£20 million) in funding under ERASysBio+, an initiative involving ministries and
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Body clock drugs could ease psychiatric disorders and jet lag - MRC…
https://www2.mrc-lmb.cam.ac.uk/body-clock-drugs-could-ease-psychiatric-disorders-and-jet-lag/24 Aug 2010: “Researchers have successfully used a drug to reset and restart the natural 24 hour body clock of mice in the lab. The ability to do this in a
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Bizarre love triangle: first amoebal sex-determining system…
https://www2.mrc-lmb.cam.ac.uk/bizarre-love-triangle-first-amoebal-sex-determining-system-discovered/17 Dec 2010: The key genes responsible for determining the amoebal sexes are not related to any known in other organisms, showing that a completely new mode of sex-determination has been discovered.
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Body clock drugs could ease psychiatric disorders and jet lag - MRC…
https://www2.mrc-lmb.cam.ac.uk/body-clock-drugs-could-ease-psychiatric-disorders-and-jet-lag-2/26 Aug 2010: into a new rhythm.”. ... If further studies in humans confirm what this study has shown in mice, this could eventually lead to an entirely new approach to treating mental illnesses such as bipolar disorder.”.
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Understanding how toxins can affect the mechanism of the ribosome -…
https://www2.mrc-lmb.cam.ac.uk/understanding-how-toxins-can-affect-the-mechanism-of-the-ribosome/18 Oct 2010: Dr Venki Ramakrishnan’s lab from the LMB’s Structural Studies Division have uncovered the molecular mechanism by which toxins such as ricin and
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Venki Ramakrishnan elected Honorary Fellow of the Academy of Medical…
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-elected-honorary-fellow-of-the-academy-of-medical-sciences/5 Jul 2010: This information is critical in developing new antibiotics to combat infection and disease.
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Venki Ramakrishan chosen for 'Padma Vibhushan', India's…
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishan-chosen-for-padma-vibhushan-indias-highest-civilian-award/28 Jan 2010: “Padma Awards, the country's highest civilian awards, are conferred in three categories, namely, Padma Vibhushan, Padma Bhushan and Padma Shri...
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3D structure of PI3Kdelta: An important drug target for a wide range…
https://www2.mrc-lmb.cam.ac.uk/3d-structure-of-pi3kdelta-an-important-drug-target-for-a-wide-range-of-diseases/13 Jan 2010: Published on. 13 January, 2010. “Intellikine announced today the publication of an article entitled, “The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors,” now available as
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Geoffrey Grigg Traveling Fellowship established between LMB and the…
https://www2.mrc-lmb.cam.ac.uk/geoffrey-grigg-traveling-fellowship-established-between-lmb-and-the-garvan-institute/26 May 2010: LMB and the Garvan Institute, Sydney, Australia have set up the Geoffrey Grigg Traveling Fellowship aimed at enabling short scientific exchange visits
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Biography captures Sydney Brenner's unflagging scientific…
https://www2.mrc-lmb.cam.ac.uk/biography-captures-sydney-brenners-unflagging-scientific-curiosity-and-lively-personality/23 Sep 2010: The new book Sydney Brenner: A Biography, written by Errol C.
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Tom Peck: Yet another triumph for the place they call 'the Nobel…
https://www2.mrc-lmb.cam.ac.uk/tom-peck-yet-another-triumph-for-the-place-they-call-the-nobel-prize-factory/2 Nov 2010: “The lab got its 14th Nobel award last year. It traces its roots back to the discovery of the DNA double helix. Revelations about man's abilities to
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Endocytosis: Curvature proteins direct traffic
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/NRMCB_Fcho.pdf18 Jun 2010: In support of this, overexpression or knockdown of FCHO1 and FCHO2 altered the nucleation rate of CCPs, as determined by the number of new CCPs per unit area per second. ... Together, these results reveal a new piece of the CCP assembly puzzle and -
Heptares Therapeutics extends multi-fte chemistry collaboration with…
https://www2.mrc-lmb.cam.ac.uk/heptares-therapeutics-extends-multi-fte-chemistry-collaboration-with-oxygen-healthcare-o2h/21 May 2010: “Executives from Heptares Therapeutics (Welwyn Garden City, UK) and O2h (Cambridge, UK) announced today an extension of the agreement under which O2h
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Jason Chin awarded the Louis-Jeantet Young Investigator Career Award…
https://www2.mrc-lmb.cam.ac.uk/jason-chin-awarded-the-louis-jeantet-young-investigator-career-award-and-elected-to-embo-membership/3 Dec 2010: This award will allow Jason to extend his pioneering work on reprogramming the genetic code into new areas. ... EMBO New Members Press Release. Primary Sidebar. Search. Search this website.
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An Austrian biotech firm that moved into Cambridge in 2008 has raised …
https://www2.mrc-lmb.cam.ac.uk/an-austrian-biotech-firm-that-moved-into-cambridge-in-2008-has-raised-7-2m-eur-8m/6 Jan 2010: “f-star, which has developed novel antibody engineering technology, moved to the Babraham Research campus in March 2008 in order to build closer
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pnas201014665 19609..19610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Nogales-19609-10.pdf11 Nov 2010: for some years now brought to our atten-tion the conservation of the actin andtubulin cytoskeletons across kingdomsthrough their structural studies (1, 2), arenow giving us new striking images to thinkabout ... 1). Thechange is driven by a new structural -
Bicycle Therapeutics signs license agreement with EPFL and adds SR…
https://www2.mrc-lmb.cam.ac.uk/bicycle-therapeutics-signs-license-agreement-with-epfl-and-adds-sr-one-and-svls-to-seed-syndicate/29 Apr 2010: Published on. 29 April, 2010. “Bicycle Therapeutics Ltd, a new biotechnology company developing a novel technology platform for the identification and optimisation of chemically constrained cyclic peptides with high target specificity
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tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial-2.pdf16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.]. -
Flash frozen under the electron microscope: Examining the mechanical…
https://www2.mrc-lmb.cam.ac.uk/flash-frozen-under-the-electron-microscope-examining-the-mechanical-properties-of-alzheimers-amyloid-fibrils/3 Feb 2010: “By using electron microscopic images of flash frozen samples, researchers have now been able to examine the exact structure of Alzheimer's amyloid
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validation-tutorial.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/validation-tutorial.pdf7 Feb 2010: Tutorial: Validation with Coot. CCP4 Workshop New Delhi 2010. February 7, 2010. -
Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…
https://www2.mrc-lmb.cam.ac.uk/moments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing/6 Dec 2010: “Nobel laureate Venki Ramakarishnan describes how James Watson discovered DNA base pairing which showed how the DNA double helix could carry
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A cure for the common cold may finally be achieved as a result of a…
https://www2.mrc-lmb.cam.ac.uk/a-cure-for-the-common-cold-may-finally-be-achieved-as-a-result-of-a-remarkable-discovery-in-a-cambridge-laboratory/2 Nov 2010: The discovery opens the door to the development of a new class of antiviral drugs that work by enhancing this natural virus-killing machinery of the cell. ... Scientists believe the first clinical trials of new drugs based on the findings could begin
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tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial-2.pdf16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.]. -
emulator as well as a solid understanding of its ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Traub&Wendland2010.pdf1 Jun 2010: This brings the system into a new interacting ground state. c, The new ground state is characterized by identifying the state of the individual ions. ... discover novel quantum phenomena, identify new quantum phases or just design interest-ing quantum -
Supplementary data 15 4 10
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099s1.pdf15 Apr 2010: 2008. A novel component of the division-site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD. -
ligand-fitting-tutorial.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/ligand-fitting-tutorial.pdf3 Mar 2010: Tutorial: Ligand Fitting with Coot. CCP4 Workshop New Delhi 2010. March 3, 2010. ... The centre of the screen is a bit crowded now. Undisplay those new ligands. -
www.landesbioscience.com Autophagy 805 Autophagy 6:6, 805-807; August …
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20574157.pdf2 Aug 2010: Further devel-opment of inhibitors guided by struc-tures could lead to a new generation of improved inhibitors with applications as chemical tools to investigate PtdIns(3)P-dependendent pathways and -
tutorial.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial.pdf21 Jan 2010: Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms. ... 15. • Now optimize the fit of this new residue with Real Space Refinement. -
73687_Trans
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099s2.pdf28 Apr 2010: There are still questions about how the structure recognizes the very slight curvature of the polar membrane, but the new structural information greatly advances the discussion. -
DOI: 10.1126/science.1184429 , 1638 (2010); 327Science et al.Simon…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20339072.pdf2 Aug 2010: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... This can becrucial in the design of new generations of Vps34inhibitors with improved specificity, solubility,and cellular -
201010176 1..6
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Aylett-TubZ.pdf21 Oct 2010: The identificationof quadruple as well as double filaments posed a new question,however: Which filament is present in cells? ... Both formed filaments similar to those of native TubZ. We then reconstructed the new filaments in three dimensionsto reveal -
Bacterial actin MreB assembles in complex with cell shape protein RodZ
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf17 Feb 2010: References. Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ,Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC(2002) PHENIX: building new software for automated crystal-lographic ... Mol Microbiol 51:1321–1332. Gerdes K (2009) -
Many bacterial plasmids are maintained at low copy number ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro2425.pdf14 Sep 2010: Filaments stabilized in this way continue to polymerize with the addition of new ParM subunits at both ParR–parC-capped ends, although the actual rate of elongation of an individual -
©20 10 N atur e A mer ica, Inc. ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20081827.pdf2 Aug 2010: We devised a new expression and purification strategy by introducing a TEV protease. ... All propeller-shaped inhibitors create a new specificity pocket not present in the apo form of the enzyme.
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