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  2. PPL number: | Granted: 08 Mar 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/oxygen_sensing_and_nutrient_signalling_in_metabolic_disease_redacted.pdf
    18 Jun 2021: Chiefly, we are interested in developing new understanding of nutrient signalling (e.g. ... As such, our work may highlight new uses for existing compounds or indicate new targets for future compounds.
  3. PPL number: | Granted: 10 Jun 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf
    13 Sep 2021: Hence, there is an urgent need for new and safe drugs that successfully reverses or prevents progression of liver injury in patients with NASH. ... Page 4 of 7. By researching on new targets for such related diseases is a clear unmet clinical need.
  4. PPL number: | Granted: 10 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/cellular_and_molecular_mechanisms_of_the_mouse_embryo_development_nts_redacted.pdf
    13 Sep 2021: fostering of new international collaborations that will allow new approaches to current and future scientific questions. - ... Subsequently, the new mouse line would be used to obtain embryos for the experiments as described above.
  5. PPL number: | Granted: 12 Nov 20 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_of_novel_compounds_for_the_treatment_of_dementia._nts_redacted.pdf
    19 Aug 2021: Page 2 of 9. What's the aim of this project? Our aim is to identify and validate new mechanisms for treating dementia, to identify novel, drug-like compounds that work ... Who or what will benefit from these outputs, and how? Data on new drug targets may
  6. PPL number: | Granted: 16 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/developing_therapeutic_drugs_for_cancer_including_the_establishment_of_tumour_models_nts_redacted.pdf
    13 Sep 2021: It is estimated that by 2040 there will be 27.5 million new cases of cancer each year. ... We ensure small-scale pilot or tolerability studies are carried out for new tumour types, experimental methods, or therapies.
  7. PPL number: | Granted: 11 Nov 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_adaptive_human_immune_systems_and_their_application_for_drug_and_vaccine_discovery_nts_redacted.pdf
    19 Aug 2021: Why is it important to undertake this work? It is important to undertake this work so that we can discover new drugs and better vaccines for treating and preventing many different ... New medicines, namely vaccines and drugs. Drugs that offer potential
  8. University of Cambridge AWERB Handbook Version 6.6 2nd March ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/02.03.2021_awerb_handbook_6.6_external.pdf
    3 Mar 2021: from the AWERB Standing Committee to consider the 3Rs sections of some new project licence. ... where new or revisions are necessary to Standard Operating Procedures [SOPs] and implement University.
  9. PPL number: | Granted: 12 Jun 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_vulnerability_to_impulsivecompulsive_spectrum_disorders_-_optimisation_and_redacted.pdf
    19 Aug 2021: Similarly, it would not be possible to develop new treatments for brain disorders without testing them in animal models first. ... Thus, our recent work on environmental enrichment has actually shed new light on the rather anthropomorphic view of the
  10. PPL number: | Granted: 08 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/regenerative_neuroimmunology_applied_to_progressive_multiple_sclerosis_research_nts_redacted.pdf
    13 Sep 2021: This will create new opportunities to test new therapies that can stop bad inflammation. ... This will also provide us the opportunity to build new collaborations locally and internationally.
  11. PPL number: | Granted: 28 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/epithelial_stem_cell_behaviour_away_from_homeostasis_translational_relevance._nts_redacted.pdf
    13 Sep 2021: By disseminating our observations from early stages, for example via conferences, we create new collaborations with experts in research fields beyond our own. ... Methods and datasets generated in these types of analyses are made publicly available as

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