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Julian Gough wins Academic Entrepreneur of the Year award - MRC…
https://www2.mrc-lmb.cam.ac.uk/julian-gough-wins-academic-entrepreneur-of-the-year-award/22 Sep 2020: Julian Gough has been named the Cambridge Enterprise Academic Entrepreneur of the Year for his work with Mogrify.
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Structural clues for influenza virus assembly and disassembly - MRC…
https://www2.mrc-lmb.cam.ac.uk/structural-clues-for-influenza-virus-assembly-and-disassembly/9 Sep 2020: To do this, Julia infected mammalian cells with influenza A virus, leading to production of new viruses. ... Influenza causes very large numbers of cases of severe disease and death every year and new flu strains can cause global pandemics.
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Alan Fersht and Marta Zlatic win Royal Society Medals - MRC…
https://www2.mrc-lmb.cam.ac.uk/alan-fersht-and-marta-zlatic-win-royal-society-medals/4 Aug 2020: I was thrilled to receive the news and extremely honoured that our work has been recognised in this way.”.
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SARS-CoV-2 disrupts the brain barrier in human organoids - MRC…
https://www2.mrc-lmb.cam.ac.uk/sars-cov-2-disrupts-the-brain-barrier-in-human-organoids/16 Oct 2020: They found that the virus is able to infect and produce new virus inside ChP epithelial cells, but neurons and glia were not susceptible to infection. ... With the excellent support of my supervisor, Madeline Lancaster, and the expertise of Leo James’s
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Wanda Kukulski: Unlocking the secrets of membrane biology - MRC…
https://www2.mrc-lmb.cam.ac.uk/wanda-kukulski-unlocking-the-secrets-of-membrane-biology/6 Mar 2020: Correlative light and electron microscopy is a relatively new technique, and especially when combined with electron cryo-tomography, what you can see is spectacular: “It’s like watching wildlife channels”, Wanda
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Put your genes to work: contribute to medical research - MRC…
https://www2.mrc-lmb.cam.ac.uk/put-your-genes-to-work-contribute-to-medical-research/14 May 2020: Julian Gough and his group are crowdsourcing raw genomic data for a phenotype prediction study…
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Charles Darwin’s hunch about early life was probably right - MRC…
https://www2.mrc-lmb.cam.ac.uk/charles-darwins-hunch-about-early-life-was-probably-right/12 Nov 2020: BBC FUTURE article looking back at origin of life research breakthroughs, including key research by John Sutherland that utilised UV light to form the
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A cellular pacemaker in the central body clock - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/a-cellular-pacemaker-in-the-central-body-clock/7 Jul 2020: Our daily cycle is controlled by a central clock known as the SCN, but it has been unclear how the network of cells that make up the SCN generate the properties that make it a strong clock. Michael Hastings’ group has identified a signalling axis
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RNA Society Spotlight on LMB postdoc Jailson Brito Querido - MRC…
https://www2.mrc-lmb.cam.ac.uk/rna-society-spotlight-on-lmb-postdoc-jailson-brito-querido/22 Sep 2020: This month’s RNA Society Spotlight features Jailson Brito Querido, a postdoctoral researcher in Venki Ramakrishnan’s group. Jailson describes how he
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First look at the atomic structure of thyroglobulin - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/first-look-at-the-atomic-structure-of-thyroglobulin/5 Feb 2020: Thyroglobulin, the protein precursor to the thyroid hormones T3 and T4, is the only molecule in the human body that is modified by iodine, and the modification directly leads to the formation of the thyroid hormones in the thyroid gland. But the
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Elyse Fischer wins the IUBMB Whelan Young Investigator Award - MRC…
https://www2.mrc-lmb.cam.ac.uk/elyse-fischer-wins-the-iubmb-whelan-young-investigator-award/16 Nov 2020: Elyse Fischer, a PhD student in David Barford’s group, receives the award for her work on the molecular mechanisms of chromosome segregation during cell division.
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Hayley Sharpe wins a 2020 Lister Institute Research Prize - MRC…
https://www2.mrc-lmb.cam.ac.uk/hayley-sharpe-wins-a-2020-lister-institute-research-prize/13 Aug 2020: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is one of four researchers to be awarded a 2020 Lister Institute
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The many strange long-term symptoms of Covid-19, explained - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-many-strange-long-term-symptoms-of-covid-19-explained/18 Dec 2020: Article looking at the varied long-term effects of Covid-19 and the clues that latest research offers into what might be causing all the symptoms –
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First structures of α-synuclein filaments from human brain - MRC…
https://www2.mrc-lmb.cam.ac.uk/first-structures-of-%CE%B1-synuclein-filaments-from-human-brain/28 May 2020: New research from the groups of Michel Goedert and Sjors Scheres has revealed the first structures of α-synuclein filaments from human brain.
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TRIM21 links antibody and T cell immunity to combat viral infection - …
https://www2.mrc-lmb.cam.ac.uk/trim21-links-antibody-and-t-cell-immunity-to-combat-viral-infection/4 Dec 2020: This reveals a new mechanism of immune synergy between antibodies and T cells, which are often thought to work quite separately. ... Therefore, this work provides multiple new concepts that could be exploited in the development of treatments for and
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Ankyrins: a missing molecular link in mechanical senses - MRC…
https://www2.mrc-lmb.cam.ac.uk/ankyrins-a-missing-molecular-link-in-mechanical-senses/22 Apr 2020: Hearing and touch depend on the ability of sensory neurons to be activated by a force, such as pressure or vibration from sound, and then pass information on to the brain. William Schafer’s group has identified some of the key proteins that make
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Science Magazine dives into the science behind affordable cryo-EM -…
https://www2.mrc-lmb.cam.ac.uk/science-magazine-dives-into-the-science-behind-affordable-cryo-em/24 Jan 2020: In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard
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Coot Cryo-EM Tutorial 2: Fitting and Mutating | Coot Development Blog
https://www2.mrc-lmb.cam.ac.uk/coot/blog/2020/10/20/Coot-Cryo-EM-main.html20 Oct 2020: Compare this maps with the original. You should find that the new (smooth) map is easier to understand. ... use the Display Manager to delete the first (mrc) map. Change the contour Step for the new Maps:. -
Revolutionary microscopy technique sees individual atoms for first…
https://www2.mrc-lmb.cam.ac.uk/revolutionary-microscopy-technique-sees-individual-atoms-for-first-time/4 Jun 2020: Sjors Scheres’ and Radu Aricescu’s groups have pushed the boundaries of cryo-EM, allowing the technique to detect individual atoms in a protein for the
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From dawn to dusk: a day in the life of an LMB PhD student - MRC…
https://www2.mrc-lmb.cam.ac.uk/from-dawn-to-dusk-a-day-in-the-life-of-an-lmb-phd-student/28 Oct 2020: Published on. 28 October, 2020. Karen in the Lab. When the LMB Director, Jan Löwe, ran an internal video competition for staff and students to submit ideas for new films about ... I’ve always been interested in using our knowledge of biological
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