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FtsA forms actin-like protofilaments
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBO2012FtsAPiotr/emboj201276a.pdf27 Mar 2012: protofilament architecture (Figures 2A and 3). Inspection of our new FtsA/FtsZ crystal structure. ... in a Beckman TLA100rotor for 30 min, supernatants transferred to new tubes and GTP(in case of FtsZ) or ATP (in case of ParM-Z hybrid) to a -
Regulation of lipid binding underlies the activation mechanism of…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22120714.pdf21 Nov 2012: The p110 delta structure: mechanisms for selectivity andpotency of new PI(3)K inhibitors. -
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS PSTPIP2 deficiency in mice …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Blood-2012-Chitu-3126-35.pdf12 Oct 2012: immune system and has ledto the emergence and rapid development of the new field ofosteoimmunology.32,33 In this paper, we focused on the elucidationof the actions of the anti-inflammatory ... a New York Community Trust Blood Diseases Grant (V.C.);and an -
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https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/vadas_science_signaling.pdf5 Dec 2012: byAssociation for the Advancement of Science, 1200 New York Avenue, NW, Washington, DC 20005. ... cells. Our data suggest that GPCR-mediated activation ofPI3Kb could provide a new target for the design of anticancer therapeutics. -
4380 | G. J. Doherty et al. Molecular Biology ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Doherty2011/DohertyGRAF_MBC2011.pdf17 Jan 2012: For quantification of the colocalization between CTxB and PLAs, 3–10 separate images of each condition were thresholded for the bright-est areas; overlapping areas were then transferred into a new -
A Ubiquitin Ligase-Associated Chaperone Holdase Maintains…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/72_Wang_Q_Mol_Cell_2011.pdf23 May 2012: extracts containing 0.5% SDS with 2 ml Endo H (New England BioLab) in the.
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