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  2. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  3. news and views NATURE CELL BIOLOGY VOL 4 OCTOBER ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/ncb1002-e229.pdf
    23 Sep 2002: news and views. NATURE CELL BIOLOGY VOL 4 OCTOBER 2002 www.nature.com/naturecellbiology E229. ... Adding to the existing ideas, this exciting new model willno doubt spur further research into the understanding of theforces underlying vesicle formation.
  4. Job description and person specification template

    https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=1206147
    1 Feb 2024: To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required. ... moving into a new research discipline and/or needs to further develop their
  5. 1 JED: Questions Arising ● Does the Acedrg new ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/JED-questions-arising.pdf
    30 Sep 2017: i.e., use the same description and apply it to the new ligand in question, just like for sugar links. ... generated by Acedrg's new mode). We don't have anything new to offer for modifications.
  6. Impress

    https://www2.mrc-lmb.cam.ac.uk/coot/ephemera/beyond-coloured-lines.pdf
    28 Sep 2020: how depth is represented in 3D applications– problems with the current representation– Screenshots: how New Coot is an improvement on Old Coot. ... Ambient New Lighting Model:. – Ambient, Diffuse, Specular, Fresnel, Ambient Occlusion– Not yet:
  7. 1 Clear StrategyTM Screen I MD1-14 A 6 × ...

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB10.pdf
    2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to
  8. KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=21355
    27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  9. 1 CURRICULUM VITAE Venki Ramakrishnan Nationality U.S.A. (since 1985) …

    https://www2.mrc-lmb.cam.ac.uk/groups/ribo/download/ramakrishnan_cv_brief.pdf
    4 Jan 2024: The New Science of Aging and the Quest for Immortality 2024: Hodder and Stoughton (UK); William Morrow/HarperCollins (USA) SCIENTIFIC PUBLICATIONS Can be looked up through
  10. LMB Rising Talent Fellowship Additional Information 1. Is the ...

    https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=1206082
    2 Feb 2024: This Fellowship is for scientists who have a PhD in a relevant subject (or are due to complete PhD within 6 months), are moving into a new research discipline or have ... Postdoc induction and buddy system for new starters A postdoc buddy is a fellow
  11. A Coot for Cryo-EM: 0.9 (pre-release) ● ~1500 revisions ...

    https://www2.mrc-lmb.cam.ac.uk/coot/ephemera/CCP4-wg2-whats-new-in-Coot-2019.pdf
    28 May 2019: A Coot for Cryo-EM: 0.9 (pre-release). 1500 revisions ahead of the master branch This new branch is actively developed Considerations for the CootVR interface. ... Ignore it. – new Coot on Mac OS X and Windows doesn't matter.
  12. MD1-118 Hippocrates additive screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/Addit-03.pdf
    9 Jul 2018: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.
  13. 27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  14. MAX PERUTZ LECTURE Tuesday 27th April at 4pm on ...

    https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=20346&ind=1618825570921
    25 Mar 2021: The coming of age of de novo protein design. https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  15. KWRM_A_992668_O

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf
    20 Oct 2015: Engineering new synaptic connections in the C.elegans connectome. Ithai Rabinowitch & William R Schafer. ... 3B, right), presumablydue to negative charge flowing fromAWC into AIY through the new electricalsynapse (Fig.
  16. Setting the stage: development of sample holders for electron ...

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=21295
    21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.
  17. Endocytosis: Curvature proteins direct traffic

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/NRMCB_Fcho.pdf
    18 Jun 2010: In support of this, overexpression or knockdown of FCHO1 and FCHO2 altered the nucleation rate of CCPs, as determined by the number of new CCPs per unit area per second. ... Together, these results reveal a new piece of the CCP assembly puzzle and
  18. Date: 4-5th April 2011 Venue: School of Biosciences, University ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/BirminghamProgram.pdf
    4 Mar 2011: Trains run from New Street Station to University Station roughly every 10 minutes. ... £60-80 Britannia Hotel Birmingham New Street, B2 4RX Price range: £65-£70.
  19. Prel progr with speakers

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/Prog_PCH_conference.pdf
    25 Jul 2007: Markus Plomann, Cologne, D Britta Qualmann, Magdeburg, D Ann Siehoff-Icking, Frankfurt, D Richard Stanley, New York, USA. ... Alan Munn, Brisbane, Australia. Mohan Balasubramanian, Singapore. 16:45 Coffee break 17:15 Keynote lecture Pietro de Camilli,
  20. Document2

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/2009BARprogram.pdf
    20 May 2009: 11:00-11:25 Andrew Craig, Kingston, Canada 11:30-11:55 Richard Stanley, New York, USA 12:00-12:25 Presentation selected from the abstracts 12:45-14:00 Lunch
  21. 318-320 News Feat Curves MH.indd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/NatureAheadCurve.pdf
    17 Jul 2009: The pictures came from an experiment carried out by Kohji Takei, De Camilli’s postdoc at Yale University in New Haven, Connecticut. ... The new helix “is a start to explaining why the Golgi has this beautiful architecture”, says Antonny.
  22. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  23. Meet our worms!Our worms have a long name: Caenorhabditis ...

    https://www2.mrc-lmb.cam.ac.uk/groups/worms/download/Meet-our-worms_worksheet.pdf
    18 Jan 2018: For example, we can introduce new DNA (i.e. make transgenic animals), to express fluorescent proteins in our cells of interest, or we can silence genes to find out what they
  24. J. Mol. Biol. (1974) 87, 641-656 Electron Microscopy of ...

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jmb74.pdf
    26 Jun 2024: They were however also estimated from the azimuthal data alone. Such an inde- pendent estimate gave new values for the scale factors and axial shifts differing by not more than. ... The positioning indicated in Plate III(b) is the only possibility. This
  25. Dinolite instructions

    https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions.pdf
    6 Jun 2011: This information is also automatically saved. 3. To take a new image, place your mouse over anything other than an existing thumbnail.
  26. MD1-98 The LMB Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB21.pdf
    15 Jul 2016: Features of The LMB Crystallization Screen: • A brand new set of the most successful.
  27. validation-tutorial.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/validation-tutorial.pdf
    7 Feb 2010: Tutorial: Validation with Coot. CCP4 Workshop New Delhi 2010. February 7, 2010.
  28. PII: 0304-3991(84)90197-9

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/ultram84.pdf
    26 Oct 2008: The new lower specimen translation plate has the same overall dimensions as the original one (fig. ... The new specimen cartridge has a 2”-tapered copper body with a stainless steel sleeve and pin, shaped as for the original cartridge to permit.
  29. Model-Building with Coot Adding N-linked Glycosylation& Demo Paul …

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-may-2017-aca-new-orleans.pdf
    29 May 2017: Added into a new N-linked tree: – paucimannose. 23/40. Xyl-β1,2. Xyl - β1,2 – Man – using XYP (beta D xylosepyranose). – ... both GUI interface and built into the auto-builder. New Interface.
  30. MD1-93 the Morpheus Additive Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/Addit-01.pdf
    5 Jul 2018: The Morpheus Additive Screen is a new 96-condition additive screen, containing an extensive library of ligands suitable for soluble and membrane proteins.
  31. In this activity, students use a template to make ...

    https://www2.mrc-lmb.cam.ac.uk/viruswars/images/VirusWars_TeachersNotes.pdf
    27 Jun 2013: Describe the different shapes of viruses and the process viruses use to infect a host cell, replicate, and infect new viruses. ... Ã Understanding how TRIM21 and antibodies work may help scientists devise new therapies for virus infection.
  32. https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/protocols

    https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/M4S_activities.pdf
    11 Mar 2022: Yeasts reproduce by budding (asexual reproduction), when a small bud forms and splits to form a new daughter cell, but under stress conditions they can produce spores (a form of sexual
  33. pnas201014665 19609..19610

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Nogales-19609-10.pdf
    11 Nov 2010: for some years now brought to our atten-tion the conservation of the actin andtubulin cytoskeletons across kingdomsthrough their structural studies (1, 2), arenow giving us new striking images to thinkabout ... 1). Thechange is driven by a new structural
  34. tutorial-2.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial-2.pdf
    16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.].
  35. FigS1

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SchmidBetaPaper/BetaHubSup.pdf
    7 Sep 2006: GST-α. Pulldown from rat brain cytosol. numbers in brackets indicate peptide numbers bold are new interaction partners found in this Mass Spec analysis. ... GST-β1. Pulldown from rat brain cytosol. GST-α GST-β2. numbers in brackets indicate peptide
  36. MD1-118 Hippocrates additive screen

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/LMB%20plates/Addit-03.pdf
    13 Oct 2020: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.
  37. Ligand Sketcher Review (Open Source) Rob Nicholls…

    https://www2.mrc-lmb.cam.ac.uk/coot/ligands/2016/nicholls-2016_Sept_Ligands.pdf
    26 Sep 2016: Do we even need something new? • Jligand. • Already part of CCP4 • Not really developed • 3D not 2D • Java. •
  38. NSMB0607 RH.indd

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/nsmb0607-467.pdf
    18 Jun 2007: Now, MacKinnon and colleagues have used isothermal titration calorimetry (ITC) and new structural data to investigate how ions are selected by KcsA and the contributions they make in promoting the conductive
  39. “Coot for SHELXL” Tutorial Paul Emsley & Judit É ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/coot-shelx.pdf
    27 Aug 2022: Select ValidateDifferenceMap Peaks. and hit Find blobs. [The new pop-up contains a clickable list of difference density blobs. ... 7. [We are given a new window to pick what kind of atom/molecule we wishto place here.].
  40. HiroseSuppl

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/supp_MC2006.pdf
    25 Aug 2006: tubulin (orange arrowhead). This new position of helix α4 in the empty state is lower in.
  41. JCSG+ Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB11.pdf
    2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to
  42. Keith_Ligand_Meeting_Dec2016

    https://www2.mrc-lmb.cam.ac.uk/coot/ligands/2016/Keith_Ligand_Meeting_Dec2016.pdf
    9 Dec 2016: Dictionary entries. New coordinates (C2), based on above dictionary and REFMAC potentials.
  43. PII: S1097-2765(02)00692-5

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/23_Hegde_RS_Mol_Cell-2002.pdf
    22 Oct 2002: 2001). Acta Oncol. 40,. 689–695.Peter MacCallum Cancer Institute. subtle implication of this remarkable flexibility remainsTargeting and Beyond:largely ignored.New Roles for Old The ability to tolerate tremendous diversity ... Two new studies (Weihofen
  44. Science Magazine

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/sciencetubzactinglikeactin.pdf
    5 Jan 2011: Because the studied compound, HgBa. 2CuO. 4δ,. is thought to be representative of the cuprates, and the new magnetic excitation appears at the same T. ... MedicineIntegrating Medicine. and Science. The new journal from the publisherof Science stands at
  45. Cryo-EM Model-Buildingwith Modern Coot Paul Emsley@ Ben Gurion…

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-2020-nov-slac.pdf
    10 Nov 2020: Where does Cryo-EM Coot fit into the various builds/releases? What's new in 0.9 and how does it help? –
  46. 1674rr

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Snx1PeteCullen2004/Snx1JCBRoundup.pdf
    23 Nov 2004: new computational model from Scott Bornheimer, Shankar Subra-maniam, and colleagues (University of California, San Diego, CA)predicts how the GTPase cycle operates in one of several modes.
  47. Pymol guide

    https://www2.mrc-lmb.cam.ac.uk/groups/nagai/download/pymolguide.pdf
    19 Dec 2017: So if you click on (sele) you can toggle and untoggle your new selection. ... So if you want to make a new selection, make sure you deselect everything first!
  48. LIGANDS Meetings ● Previously:– Developer → Users ● Now ...

    https://www2.mrc-lmb.cam.ac.uk/coot/ligands/2016/emsley-ccp4-ligands-dec-2016.pdf
    9 Dec 2016: Re-refine. In the updated, Acedrg dictionary, the atom names are the same, one bond is different– Read old model and use new dictionary. – ... I'd rather work in coot and submit refinement jobs, and import and export new models and ligands. –
  49. Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf
    26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C,
  50. tutorial-2.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial-2.pdf
    16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.].
  51. EMBO Practical Course on the Crystallization of Macromolecular…

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/cv/2020_01_Carter_CV.pdf
    31 Jan 2020: HONOURS AND AWARDS: Apr 2018 Wellcome Investigator Award May 2016 EMBO Membership Dec 2012 Wellcome Trust New Investigator Award Nov 2012 EMBO Young Investigator Program Oct 2010 Elected Fellow of Clare ... Curriculum vitae. Other activities 2020

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