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5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

3 Jun 2024: Pluripotent stem cells have the unique capacity to generate all the cell types of the organism. In the embryo, they undergo concomitant changes in shape

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Emeritus.

24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

14 Mar 2024: In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids.

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Chris Tate

1 Jul 2024: Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the Molecular Immunity Unit, receives the award in recognition of her pioneering research into tuberculosis.

23 Feb 2024: Science News : Scientists have mapped an insect brain in greater detail than ever before. ... Sky News : First map of insect brain signals 'big step forward' in understanding thoughts.

18 Mar 2024: Ultimately, mycobacteria can cause granuloma breakdown by inducing programmed macrophage death, a step that further increases bacterial growth and promotes transmission to new hosts. ... Our findings have been borne out in humans and are informing new

22 Mar 2024: Thus, understanding their cell biology requires re-thinking some of our most basic assumptions (bilayers membranes) and the development of new research tools and methods (high-temperature live cell imaging).

21 Jul 2023: Current Vacancies Listed below are the vacancies currently being advertised. In addition we welcome speculative applications from postdocs – see Postdoc

23 Feb 2024: Information transfer in the nervous system occurs at synapses, where presynaptic signals are interpreted by postsynaptic receptors. We study this process

24 Oct 2023: Perutz Student Prize The Perutz Student Prize is awarded annually for outstanding work performed at LMB prior to the award of a Ph.D. Nominees

21 Jul 2023: For a list of recent news items please see the LMB News section.

24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

21 Jul 2023: The LMB moved into a new, modern building in February 2013, on the Cambridge Biomedical Campus. ... A new type of immune cell, that can initiate allergic asthma, has been found.

29 Jan 2024: Dendritic cells (DCs) play a key role in initiation of cytotoxic immune responses against pathogens and tumours. In order to prime the relevant T cells,

23 Feb 2024: Our research is aimed at understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome

21 Jul 2023: Since retirement in 2010 he has been working part-time in the University of Strathclyde on new types of microscope, using his ‘Mesolens’ and collaborating in published work on nonlinear optics

21 Jul 2023: The MRC, realising the potential for medical applications of these developments, provided a new building for the unit, and in 1962 the Laboratory of Molecular Biology was opened. ... Since then, the Laboratory has been a prolific source of new ideas,

14 Mar 2024: Andrew Travers started his Ph.D. at the LMB under the tutelage of the late John Smith in 1964. After this he took a couple of years out as a post-doc in

21 Jul 2023: Group Leader Profiles   Group Leaders are drawn to the LMB from all over the world, having gained experience in a variety of places. Some join the

21 Jul 2023: In conjunction with Professor Matthew Wood and colleagues at the University of Oxford, we designed a new class of cell-penetrating peptides, called Pip, which showed outstanding cell and in vivo ... The new D-PEP peptides form the basis of founding of a

23 Feb 2024: We are interested in cell autonomous innate immunity, i.e. in the ability of individual cells to defend themselves against infection. Cytosolic defence

23 Feb 2024: Splicing of precursor messenger RNA (pre-mRNA) is a ubiquitous hallmark of gene expression in all eukaryotes. Within the cell, splicing occurs

21 Jul 2023: Scientific Training Electron Microscopy Biophysics Macromolecular Crystallisation Crystallography Course 2013 Statistics Course 2014 RNA-seq course

1 Feb 2024: Design of the new building. In keeping with the original ethos of the LMB, the building has an open plan design with many communal areas to encourage interactions and discussions between ... The LMB has a number of initiatives to help employees save

13 Feb 2024: Neuronal circuits are the biological substrates for all aspects of brain function such as learning, memory, thought, speech and consciousness. The

7 Sep 2023: Using techniques including mouse genetics, fluorescence imaging and gene expression analysis we discovered group 2 innate lymphoid cells (ILC2s) as significant new participants in immune regulation through their cytokine secretion (Figure

11 Mar 2024: Marta Shahbazi, Group Leader in the LMB’s Cell Biology Division, has been announced as one of the 2024 recipients in the Life Sciences category.

22 Mar 2024: Molecular Immunity Unit Menna Clatworthy LMB Division - Molecular Immunity Unit The Clatworthy lab is interested in understanding how B cell activation

25 Aug 2023: Deorphanisation of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning..

1 Feb 2024: In 2013, the LMB moved to a new, purpose-built building designed to deliver the right environment in which innovative medical research, translation and collaboration can flourish. ... Both new and established researchers are encouraged to utilise the

2 Feb 2024: Cell shape is adapted to function. Organelle shape and local membrane architectures are likewise optimised for the processes that take place on and within

21 Jul 2023: modeling. These studies offer new approaches for tackling the challenge of antibiotic resistance.

21 Jul 2023: In 1969 Brenner and Crick invited him to the LMB to their new Cell Biology division.

21 Jul 2023: By using such a tractable model system, we can rapidly discover new pathways and dissect mechanisms that may be directly relevant to a number of human diseases, most notably cystic fibrosis ... We use high throughput yeast genetics to identify new

9 Aug 2023: Technician Commitment The LMB became a signatory of the Technician Commitment in November 2022.  We employ over 150 technical staff in a wide

13 Dec 2023: Ordered assembly of a small number of proteins within neurons and, in some cases, glia is a feature of neurodegenerative diseases. These proteins form

21 Jul 2023: LMB Exhibitions The LMB holds 3 to 4 exhibitions a year, to showcase the illustrious history of the laboratory and the cutting-edge research currently

19 Jun 2024: Keren Turton. Earlier this year, the LMB was pleased to appoint Keren Turton as the new Tissue Culture Facility Manager. ... Keren also conducts inductions for new users of the facility so researchers can independently grow cultures.

21 Jul 2023: The Graduate Student Association The LMB has an active Graduate Student Association (GSA), run by and for students, which aims to create an atmosphere of

21 Jul 2023: In collaboration with our pharmaceutical partners, we are seeking to develop HDX-MS approaches to give better insight into conformational dynamics that could result in new therapeutic strategies.

22 Nov 2023: Tobias Wauer shared his experience of volunteering at the UK Biocentre Lighthouse Lab in The Conversation: ‘My new life as a coronavirus tester’. ... The testing volunteers shared details of their experience – see: Putting science skills to new use

12 Sep 2023: In particular, LMB International Fellowships have been created for the development of innovative research, and candidates for these Fellowships would be expected to introduce new scientific projects or expertise into the ... Conversations with colleagues

21 Jul 2023: LMB@60 In 2022 we celbrated 60 years of the LMB and we collected images and other memories that relate in some way to the people that make, or have made,

21 Jul 2023: Our research has aimed to create a new generation of therapeutic agents, “bicycles”, based on highly constrained peptides with a bicyclic structure and a chemical core.

22 Mar 2024: Collaborations with the University of Cambridge LMB scientists from across the Divisions are also involved in various collaborations and initiatives with

21 Jul 2023: The LMB News team works closely with the central UKRI press office, which handles all major media stories from across the MRC’s units, centres and institutes. ... The MRC press team also provides corporate information to the media and reports on recent