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6 Oct 2023: The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the ... Andrew McKenzie’s group, in the LMB’s PNAC

20 Oct 2023: LMB Archive With a wealth of history and achievements for pioneering research in molecular biology, the LMB has created an archive to not only chart and

20 Feb 2023: Search this website. New computational method for genome analysis. New computational method for genome analysis. ... Chang Lu, a former postdoc in Julian’s group, validated the new method against three independent cohorts.

6 Jul 2023: New pathway for cells to detect bacterial infection. Published on. 6 July, 2023. ... Further experimentation by Sascha Martens, a former LMB member and now a professor at the University of Vienna, revealed that TECPR1 recruits Autophagy-Related Gene 5

18 Oct 2023: New mechanism found that maintains intracellular water balance. Published on. 18 October, 2023. ... a new mechanism that maintains optimal water availability from second to second.

6 Dec 2023: Search this website. Discovery of a new amyloid-forming protein in neurodegenerative disease. ... It represents a rare finding of a new member of the small group of proteins known to form neurodegenerative disease-associated amyloid filaments, alongside

31 Jul 2023: Every year 20-30 new graduates from the UK and all over the world join the LMB PhD programme.

21 Jul 2023: Public Engagement The LMB’s scientists work with schools, colleges, and other organisations to inspire and enthuse people about science and show how their

25 Jul 2023: News highlights from the LMB.

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Research

8 Oct 2023: Jan Löwe, LMB Director. “The LMB provides an unsurpassed environment for both new and established researchers.

6 Dec 2023: He worked closely with Fred Sanger throughout his time at the LMB, and helped develop new methods for genomic analysis – applying these to increasingly complex models. ... He helped to develop new sequencing techniques and applied these first to tRNA

21 Jul 2023: Mark S. Bretscher Curriculum Vitae Personal Details Date of Birth: 8 January 1940 Family: Married (to Barbara Pearse); one daughter (Nicola) and one son

21 Jul 2023: Current Vacancies Listed below are the vacancies currently being advertised. In addition we welcome speculative applications from postdocs – see Postdoc

24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

19 Oct 2023: Annette’s aptitude for event organising was again crucial to the Royal Opening of the new LMB building in 2013, when Her late Majesty Queen Elizabeth II and HRH Prince Philip ... A skilled writer herself, Annette also helped publicise research

9 Oct 2023: Search this website. New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug targets. ... New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug

27 Jul 2023: Search this website. New insights into how DNA synthesis is started during the process of chromosome replication. ... New insights into how DNA synthesis is started during the process of chromosome replication.

28 Sep 2023: Search this website. New method to untangle the contribution of signalling pathways involved in asymmetric cell division. ... New method to untangle the contribution of signalling pathways involved in asymmetric cell division.

4 Jul 2023: New members are elected annually by the existing membership. At the LMB, Katja investigates the mechanisms that transform epithelial sheets of cells into complex, three-dimensional organs. ... I am grateful to my past and current lab members for helping

9 Jan 2023: HIV-1 replicates inside infected cells, producing thousands of new viruses which assemble and bud from the cell surface. ... Even when IP6-deficient viruses manage to form a capsid, TIRF experiments performed by Anna Albecka and in Till Boecking’s lab

19 Sep 2023: The group undertakes independent research to develop and implement new mass spectrometry-based methods and they collaborate with LMB groups and apply these bespoke approaches to answer important biological questions. ... Catarina commented: “In 2023, a

16 Jun 2023: The SARS-CoV-2 pandemic demonstrates how quickly we can find ourselves desperately needing new antivirals and therapeutics. ... This new class of antiviral exploits molecules called Bicycles – short peptides wrapped around a small molecule kernel.

20 Nov 2023: Jill spent her early life in New South Wales, Australia. She later obtained her undergraduate and master’s degrees from the Australian National University and then her Ph.D. ... We are applying new short read genome curation methods, long-read

13 Dec 2023: Congratulations to Michel Goedert, Group Leader in the LMB’s Neurobiology Division, who has reached 40 years of service at the LMB.

21 Jul 2023: Major human erythrocyte glycoprotein spans the cell membrane. Nature New Biology, 231, 229-232 (1971). ... Asymmetrical lipid bilayer structure for biological membranes. Nature New Biology, 236, 11-12 (1972).

6 Nov 2023: In humans, neuropeptide receptors are the target of drug development for new neuropsychiatric treatments for conditions including insomnia, chemotherapy-induced nausea, schizophrenia and depression.

13 Nov 2023: The 2023 Max Perutz Lecture titled ‘Decoding the protein dance’ will be given by Paola Picotti at 11AM (GMT) on 20th November.

20 Mar 2023: We have found that Bin2 is a new component of the podosomal machinery. ... PMID: 20150444 (pdf including supplementary material and figures) (CNCR news) (Faculty of 1000 Exceptional rating).

8 Dec 2023: This allows new attachments to form even under initially low-tension conditions, thus resolving the paradox of how kinetochore-microtubule connections can reset under low-tension conditions.

11 Apr 2023: Shalini Arun Prasad has recently become Head of the LMB’s Media Prep and Glasswash Facility, an integral service to support the continuance of research.

10 Mar 2023: A new algorithm was developed to track the brain’s signal propagation across polysynaptic pathways, and then feedforward (sensory to output) and feedback pathways, multisensory integration, and cross-hemisphere interactions were ... Future analysis of

23 Oct 2023: His research focuses on the development of new tools and methods for the structural characterisation of molecules and cells.

19 Jan 2023: His identification of Hox genes in mammals has opened up a new field of highly-active research. ... new strategies using in vivo chromosome engineering to generate novel genomic rearrangements.

8 Sep 2023: New research from Anne Bertolotti’s group in the LMB’s Neurobiology Division has discovered unexpected dose-dependent activation, rather than the intended inhibition, of ISR by its kinase inhibitors.

21 Jul 2023: Cells eliminate “orphan” proteins that have failed to assemble into the molecular machines within which they normally function. Manu Hegde’s group have now elucidated the mechanism by which one type of orphan is selectively recognised and

9 Aug 2023: Despite decades of work, the role of thousands of human proteins remains unclear despite the likelihood that they participate in possibly new areas of biological function.

28 Nov 2023: This new electron microscope promises to significantly increase the accessibility of cryo-EM. ... A low-cost electron microscope maps proteins at speed, Nature News. Primary Sidebar.

14 Aug 2023: New research from Nazareno Bona and Gerry Crossan, in the LMB’s PNAC Division, has identified one of these protections against retrotransposons. ... a new site in the genome.

13 Apr 2023: Now a new study by Tanmay Bharat’s group in the LMB’s Structural Studies Division, in collaboration with Vikram Alva from the Max Plank Institute in Tübingen, reports the

6 Oct 2023: These findings are providing new insights into Parkinson’s disease, which is the most prevalent movement disorder and the second most common neurodegenerative disease, after Alzheimer’s disease.

23 Jun 2023: New research from Patrycja Kozik’s group in the LMB’s PNAC Division has discovered a new pathway of antigen transport from endosomes into the dendritic cytosol. ... This research has helped further understanding of the mechanisms behind T cell

24 Feb 2023: Published on. 24 February, 2023. Identification of new proteostatic mechanism reveals how cells respond to surface perturbations. ... reveal new insights into plasma membrane proteostasis.

2 Aug 2023: Published on. 2 August, 2023. Cryo-EM reveals that TDP-43 forms amyloid filaments with a new fold in the most common type of frontotemporal lobar degeneration. ... New research from Benjamin Ryskeldi-Falcon’s group in the LMB’s Neurobiology Division

25 May 2023: Researchers from Greg Jefferis’ group in the LMB’s Neurobiology Division have determined the highly specified neural mechanisms which allow Drosophila flies to identify and locate males by scent of a pheromone.

29 Aug 2023: Instead, the new structures illustrate for the first time that TRF1 not only interacts with the nucleosomal DNA, but also with the core histone proteins. ... diseases. This new insight into how shelterin and nucleosomes interact will be crucial for

17 Apr 2023: Leo James’ group, in the LMB’s PNAC Division, has identified surprising protein modifications that underly Trim-Away protein degradation technology, which may explain its broad applicability to degrade almost any cellular protein.

5 Sep 2023: This is what I do in such a case: first delete the residue, then add a new one with "Add Terminal Residue." then "Mutate -> Auto Fit." to the required type, then

13 Sep 2023: This study gives new insight into this process, notably the fact that NTDs are needed to regulate GluA1’s gating kinetics, and the way the receptor is recruited into the synapse. ... This opens new avenues of research to further investigate the

16 Feb 2023: Benjamin Ryskeldi-Falcon, Group Leader in the LMB’s Neurobiology Division, has been recognised for his research into the molecular basis behind neurodegenerative diseases.