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25 Aug 2022: abscessus was related to the presence of particular mutations identified by this new ‘phenogenomic’ approach. ... These findings provide proof of concept for the group’s phenogenomic approach to understanding new pathogens.

18 Mar 2022: The new synthetic genetic polymers also offer opportunities in biotechnology and promise a new class of biopolymer-based ligands and materials for applications in diagnosis and therapy.

19 Oct 2022: New research from Manu Hegde’s group in the LMB’s Cell Biology Division, in collaboration with Robert Keenan’s lab at the University of Chicago, now sheds light on the ... Their combined efforts not only led to a better understanding of the PAT

17 Feb 2022: Search this website. New method to discover protease and other hydrolase substrates in live mammalian cells. ... New method to discover protease and other hydrolase substrates in live mammalian cells.

13 Oct 2022: Search this website. Engineered polymerase enzyme presents new opportunity for quick and efficient modified nucleic acid synthesis. ... Engineered polymerase enzyme presents new opportunity for quick and efficient modified nucleic acid synthesis.

18 Mar 2022: Jennifer L. Ong, PhD. Group leader. New England Biolabs, USA. Marc d’ Abbadie, PhD.

28 Mar 2022: Building upon previous collaborative studies of these proteins, Sjors Scheres and Michel Goedert’s groups have now identified TMEM106B as a new protein which forms amyloid filaments in human brains.

16 Nov 2022: The LMB is proud to announce that we have joined the Technician Commitment as a signatory. The commitment aims to ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across

6 Oct 2022: Structure of Biological Systems, lead by Max Perutz, to join them in plans for a new laboratory.

26 Oct 2022: As with previous symposia, researchers from both academic and industry backgrounds were welcomed for stimulating talks and discussions on how new and emerging technologies could be applied to address challenging questions

18 May 2022: The new system has revealed a number of important insights into fundamental aspects of human DNA replication. ... Thus, this new system allows for novel insights specific to the human replisome.

24 Oct 2022: He leveraged his engineered enzymes to yield exciting new aptamers with unique ligands. ... This work holds tremendous potential for therapeutic benefit through in vitro evolution of new catalysts and aptamers.

18 Nov 2022: able to answer questions in new and innovative ways”.

28 Jan 2022: He developed new methods of measuring, scaling and processing X-ray data and along with Bill Longley developed a fine focus rotating anode tube which significantly reduced the number of hours ... This led to the development of a new type of camera which

21 Mar 2022: Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies. ... Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities

5 May 2022: Her group is dedicated to the development of new technologies to map molecules, cells and functional circuits and applying these to better understand signalling in mitochondria and in the mammalian brain. ... Utilising both chemical and biological methods

25 Oct 2022: Technical staff from three institutes were invited to the event to network and share inspiring career stories.

6 Oct 2022: After more than 10 years, the dideoxy sequencing technique, a brand new approach to sequencing, was developed. ... It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge.

19 Aug 2022: 19 August, 2022. New UK-based biotechnology company launched to scale and commercialise ground-breaking synthetic biology research of Jason Chin. ... Jason commented, “Over the last 20 years, we have created a cellular factory that we can reliably and

27 Oct 2022: In this lecture, I will describe our recent progress in understanding how the brain participates in the positive and negative control of adult-adult social interactions, providing a new framework to

17 May 2022: Two new papers from Lori Passmore’s group in the LMB’s Structural Studies Division seek to provide some clarity on this issue.

3 May 2022: But what if I add an extra “L” and an extra “R”; how do I parse this new action-emphrase /emthen? ... Clearly the last two points are far from being proven and new experiments could be designed, starting from the current experimental design, in

25 Feb 2022: A new study from Kelly Nguyen’s group in the LMB’s Structural Studies Division has provided structures, which reveal unprecedented insights into the molecular basis underlying how shelterin recruits telomerase,

26 Apr 2022: Over the last 40 years, Paul has spearheaded several huge and vital projects; from designing the IT system for the new LMB building and facilitating the mass shift to work from ... Pat is also an active member of the LMB Green Committee, who are

19 Apr 2022: A new study from David Barford’s group in the LMB’s Structural Studies Division, has solved the structure of the human inner kinetochore when bound to a CENP-A nucleosome, ... These new insights into how the kinetochore functions could prove

30 Mar 2022: The findings from this study present a new way of looking at the field of molecular neuroscience in general.

16 Mar 2022: Now, new research from the group has shown that Ste2 has a novel method of activation which is unique from mammalian GPCRs. ... Computational processing of the datasets led to the determination of four new Ste2 structures; a ligand-free state, an

24 Oct 2022: This provides a new paradigm which both protects valuable engineered organisms from natural invaders and safeguards the natural world from engineered genetic material. ... Jerome demonstrated that genes which use the new synthetic code could only be

19 Jul 2022: BioNTech co-founders Uğur Şahin and Özlem Türeci will discuss using mRNA technology in vaccines to treat cancer and COVID-19.

31 Aug 2022: Acute changes in the amount of CRY1 was able to reset the clocks of independent SCN to a new, common phase.

20 Jan 2022: mechanisms. A new study from Michael Hastings’ group in the LMB’s Neurobiology Division, in collaboration with Andrew Loudon at the University of Manchester, utilised advanced synthetic biological methodology, pioneered by

10 Nov 2022: The presence of breaks at origins was confirmed using a new technique called INDUCE-seq, which allows the very precise mapping of DNA break (developed by Simon Reed’s group, University

7 Sep 2022: Published on. 7 September, 2022. New structure reveals how dynein motor domains interact and how a pair of cargo adaptors use conserved sequence motifs to scaffold the motor protein complex.

20 Sep 2022: This new study establishes the existence of multiple molecular conformers of synucleinopathies. ... The new work also opens the way to the development of methods by which to produce α-synuclein filaments with structures identical to those in human brains

7 Jun 2022: Andrew McKenzie’s group, in the LMB’s PNAC Division, has found a link between tumour-related expression of the IL25 gene, innate lymphoid cells and reduced survival amongst colorectal cancer patients

14 Jan 2022: The new structures differ from those previously determined using in vitro assembled Aβ42.

22 Aug 2022: Structural study by Nigel Unwin in the LMB’s Neurobiology Division, has found that lipids of cell membranes can form ordered, hydrophobic ‘skins’ in regions of high cholesterol concentration.

11 Mar 2022: Yeasts reproduce by budding (asexual reproduction), when a small bud forms and splits to form a new daughter cell, but under stress conditions they can produce spores (a form of sexual

27 Aug 2022: Select ValidateDifferenceMap Peaks. and hit Find blobs. [The new pop-up contains a clickable list of difference density blobs. ... 7. [We are given a new window to pick what kind of atom/molecule we wishto place here.].

13 Jun 2022: Beyond the clinic, these new data challenge scientists to review how human brain cells are grown and studied in the lab.

19 Oct 2022: Coot adds new Buttons for the selected functions in the horizontal tool-bar]. • ... Click on an atom in the new ALA. [ Coot pops up a residue type chooser]. •

4 Nov 2022: Science175, 720–731 (1972). 2. R. B. Gennis, Biomembranes: Molecular Structure and Function (Springer-Verlag New York Inc.,1989). ... Nat. New Biol. 236,11–12 (1972). 4. D. Branton, Fracture faces of frozen membranes.

22 Feb 2022: at the cellular level in the laboratory and potentially develop new drug treatments. ... Growing human embryos in a new culture system that permits correct development beyond implantation and up to day 13 of development1.

13 Jun 2022: Nature Communications, doi:10.1038/s41467-022-30656-2

27 Feb 2022: 1200 New York Avenue NW, Washington, DC20005. The title Science is a registered trademark of AAAS.Copyright 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of

13 Sep 2022: Here, we discuss the mechanisms of TMD insertion, highlight the limitations ofan iterative insertion model, and propose a new hypothesis for multipass membrane proteinbiogenesis based on recent findings. ... these new components were not ob-served on

11 Apr 2022: Epistasis Maps Reveal New Protein Complexes. 8.52.2. EMC Is Linked to Membrane Protein Homeostasis. ... Second,surprisingly little new biological insight was immediately evident from simply seeing the structure,leaving one to speculate about EMC’s