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  2. PPL number: | Granted: 17 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/roles_for_genomic_instability_in_cancer_and_ageing_redacted.pdf
    18 Jun 2021: Page 3 of 10. New genes of interest will be identified and described. ... Thus, finding new biomarkers improves our ability to both detect and treat cancer.
  3. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_redacted.pdf
    18 Jun 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.
  4. PPL number: | Granted: 05 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf
    18 Jun 2021: This network will be utilised to maximise the dissemination of the new knowledge gained through this project. ... 3) By generating large quantities of human cells, where appropriate, we can continue to perform new studies using the same human cells.
  5. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf
    13 Sep 2021: The research will aid in the development of new bacterial therapies to treat cancer. ... We continuously consider their use and development in light of new experimental data.
  6. PPL number: | Granted: 12 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/promoting_proliferation_in_non-regenerative_tissues_redacted.pdf
    18 Jun 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.
  7. PPL number: | Granted: 22 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_germ_free_and_gnotobiotic_animals_service_licence_nts_redacted.pdf
    13 Sep 2021: In order to produce new mouse colonies a minority of germ-free mice will be given mammalian gut bacteria orally to produce gnotobiotic mice with a known gut flora (bacteria).
  8. PPL number: | Granted: 30 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_mechanisms_involved_in_genome_regulation_nts_redacted.pdf
    13 Sep 2021: This second part will provide new hypotheses and research avenues for future research projects about mitochondrial and neurodegenerative diseases. ... Data generated from this project will form the basis for new funding applications, and may eventually
  9. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_nts_expires2026_redacted.pdf
    13 Sep 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.
  10. PPL number: | Granted: 24 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf
    18 Jun 2021: This project will likely result in new information and publications about the following:. ... In recent years scientists have developed a new way of growing (culturing) cells in 3 dimensions.
  11. PPL number: | Granted: 02 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_regulation_of_fat_mass_and_its_association_with_metabolic_disease_redacted.pdf
    18 Jun 2021: tolerance, providing new information on how the genes under investigation impact human metabolism and health. ... or 'negative' in the same way that a trial of a new treatment would be.

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