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A new layer of complexity in GPCR signalling could explain…
https://www2.mrc-lmb.cam.ac.uk/a-new-layer-of-complexity-in-gpcr-signalling-could-explain-differences-in-receptor-function-and-drug-response/5 Nov 2020: A new layer of complexity in GPCR signalling could explain differences in receptor function and drug response. ... Nature. Nature News & Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,.
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Is cryo-EM taking over structural biology? - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/is-cryo-em-taking-over-structural-biology/11 Feb 2020: Published on. 11 February, 2020. This news story in Nature maps the revolutionary technique’s eventful journey in the structural biology field since 2012-13.
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LMB Band 6 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/animal-research/lmb-band-6/21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. LMB Band
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Cell scientist to watch – Hayley Sharpe - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/cell-scientist-to-watch-hayley-sharpe/8 Dec 2020: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is interviewed by the Journal of Cell Science about her career
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RNA Society Spotlight on Kelly Nguyen - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/rna-society-spotlight-on-kelly-nguyen/3 Jul 2020: This month’s RNA Society Spotlight has a feature on Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division. Kelly describes the
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Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models…
https://www2.mrc-lmb.cam.ac.uk/marta-shahbazi-wins-2019-3rs-prize-for-applying-new-in-vitro-models-to-study-early-embryo-development/12 Jun 2020: Search this website. Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development. ... Marta Shahbazi wins 2019 3Rs prize for applying new in vitro models to study early embryo development.
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Schafer Lab Research
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/People_Lab_Page.html11 Jun 2020: wschafer[at]mrc-lmb.cam.ac.uk. Denise Walker - Research Scientist. Nationality: British. A central theme of my previous postdoctoral research has been to combine protein biochemistry with functional and behavioural assays,. to elucidate the role of -
Patrick Chitwood wins the Birnstiel Award - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/patrick-chitwood-wins-the-birnstiel-award/8 Oct 2020: to create membraneless organelles within cells that allow selective orthogonal protein translation, meaning that non-canonical amino acids can be used to introduce new functionalities into proteins made in that part
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A novel tau fold in the neurodegenerative disease corticobasal…
https://www2.mrc-lmb.cam.ac.uk/a-novel-tau-fold-in-the-neurodegenerative-disease-corticobasal-degeneration/13 Feb 2020: These new structures also reveal the presence of additional molecules in a cavity within the filament. ... patients. Understanding how and why tau assembles into different disease-specific structures will also be beneficial for the development of new
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First structure of a fungal GPCR - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/first-structure-of-a-fungal-gpcr/2 Dec 2020: Design of new, improved drugs with fewer side-effects requires a fuller understanding of their structures.
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Championing non-aversive mouse handling - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/championing-non-aversive-mouse-handling/14 Aug 2020: Rachel introduced the new handling methods in the room she worked in to begin with. ... The next challenge was to encourage the rest of the facility to adopt the new way of working.
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Brain organoids with the potential to predict drug permeability - MRC …
https://www2.mrc-lmb.cam.ac.uk/brain-organoids-with-the-potential-to-predict-drug-permeability/12 Jun 2020: To study the development and function of the human ChP, including how CSF is made, Madeline’s group developed a new organoid model of this tissue. ... reduce the number of new drugs that fail in phase 1 clinical trials.
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The LMB welcomes Ana Tufegdzic Vidakovic as a new Group Leader - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-welcomes-ana-tufegdzic-vidakovic-as-a-new-group-leader/15 Jul 2020: Search this website. The LMB welcomes Ana Tufegdzic Vidakovic as a new Group Leader. ... Published on. 15 July, 2020. Ana Vidakovic Tufegdzi. The LMB is delighted to announce Ana Tufegdzic Vidakovic as a new Group Leader in the PNAC Division, where she
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Sydney Brenner. 13 January 1927 – 5 April 2019 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/sydney-brenner-13-january-1927-5-april-2019/3 Sep 2020: From modest beginnings Sydney became an extraordinarily influential and accomplished molecular biologist. His critical knowledge of, and insights into,
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Ampersand by Sam Shendi exhibited outside the LMB - MRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/ampersand-by-sam-shendi-exhibited-outside-the-lmb/12 Oct 2020: Ampersand by Sam Shendi. If you walk past the main entrance to the LMB, you’ll see we have a bold new sculpture standing proudly on the plinth outside the reception. ... Julian Gough, a Group Leader in the Structural Studies Division and one member of
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A simple, novel mechanism to safeguard the integrity of the human…
https://www2.mrc-lmb.cam.ac.uk/a-simple-novel-mechanism-to-safeguard-the-integrity-of-the-human-genome/21 Aug 2020: To provide a comprehensive analysis of all possible STR permutations, Pierre, working with Guillaume Guilbaud also from Julian’s group, developed a new high-throughput assay that allows measurement of DNA
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Lights, Crafts and Charity: Christmas at the LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lights-crafts-and-charity-christmas-at-the-lmb/22 Dec 2020: Fred Chapman switches the LMB Christmas lights on. LMB Director, Jan Löwe, commented: “Thank you to all at the LMB who made these events happen and came up with new ways ... all sometime in the New Year.
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How is the Fanconi Anaemia pathway activated to remove DNA lesions? - …
https://www2.mrc-lmb.cam.ac.uk/how-is-the-fanconi-anaemia-pathway-activated-to-remove-dna-lesions/17 Feb 2020: New study, led by Pablo Alcón and Shabih Shakeel in Lori Passmore’s group, in collaboration with KJ Patel in the PNAC Division, uncovers a unique molecular “clamp and pin” mechanism that activates the D2l complex, which then recruits enzymes
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Tanmay Bharat announced as EMBO Young Investigator - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/tanmay-bharat-announced-as-embo-young-investigator/1 Dec 2020: LMB Alumnus Tanmay Bharat is among 30 life science researchers within their first four years as group leaders to become EMBO Young Investigators. He joins
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Ribosomal rescue in our mitochondria - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/ribosomal-rescue-in-our-mitochondria/27 Nov 2020: Mitochondrial ribosomes are different from those in the cytoplasm of human cells and little is known about their quality control. Venki Ramakrishnan’s group has discovered a novel pathway to rescue stalled mitoribosomes and determined structures
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