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9 Nov 2018: New insight into how membrane proteins are made. Published on. 9 November, 2018. ... New research from Manu Hegde’s group in LMB’s Cell Biology Division has discovered a factor that is crucial for many membrane proteins to be oriented correctly when

8 Jul 2018: There is a new and improved Coot email list now hosted by the jiscmail service :. is the offiical mailing list behaviour guidelines. This was started on January 25th 2007, it is ... currently being investigated whether the old list archive can be merged

29 Nov 2018: Search this website. A new tool using genetic code expansion to study circadian rhythms. ... Introduction of non-canonical amino acids requires the use of a specific new tRNA.

20 Apr 2018: Over circadian night the proteins are broken down and the cycle can then re-start with the new circadian dawn.

19 Oct 2018: new biofuels, medicines, and products to make housework easier.

21 Nov 2018: Aaron was also a champion of other new developments, such as the program of large scale DNA sequencing, and as Director of the LMB greatly supported the work of John Sulston

9 Mar 2018: John Sulston, Nobel Laureate and pioneering scientist on the techniques for mapping of genomes, died on Tuesday 6th March, at the age of 75, after a short

8 Feb 2018: Cytoplasmic dynein-1, a protein that transports cargos along microtubule tracks throughout the cell, binds to dynactin and cargo adaptor proteins to carry

6 Mar 2018: Michel Goedert from the LMB’s Neurobiology Division has been awarded the 2018 Brain Prize. Michel shares the award with fellow neuroscientists Bart De

5 Oct 2018: Thus, the new research sheds light on how our body monitors its protein production assembly lines so problems can be promptly resolved before they cause cellular stress and disease. ... In a new study, Szymon investigated what ZNF598 actually recognises,

27 Feb 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures

13 Dec 2018: This approach promises to provide new insight into the acyl intermediates formed by other important enzymes. ... Nature News and Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,.

16 Nov 2018: This requires a complex set of machinery called the replisome to unwind the paired strands of DNA allowing different polymerase enzymes to produce new copies. ... A new study from Joseph Yeeles’ group in the LMB’s PNAC Division has shown the first

6 Jul 2018: This year as part of the annual MRC Festival of Medical Research, twenty-five scientists and support staff from across the MRC, including the LMB’s

6 Dec 2018: potential to revolutionise the discovery and synthesis of new classes of materials and pharmaceuticals. ... These experiments provide a key advance in the development of cell-based factories that use genetic information to encode the synthesis of new

16 May 2018: More recently, Melina’s lab, in collaboration with Dean Clift from Leo James’ group in the LMB’s PNAC Division, developed a new method for protein degradation – Trim-Away.

1 Jun 2018: Martin and Joe found for the first time that the yeast replisome can re-establish a new leading strand beyond the damage without the assistance of accessory factors, via the activity ... Martin and Joe then pinpointed down the source of this inefficiency

21 Jun 2018: Gel showing global poly(A) tail lengths which shorten over time. Scientists in Lori Passmore’s group in the LMB’s Structural Studies Division have revealed new mechanistic insights into the ... This work provides new insights into the interplay of

27 Apr 2018: Sjors Scheres, Group Leader in the LMB’s Structural Studies Division, has been awarded the Bijvoet Medal for his outstanding contribution to furthering

3 Oct 2018: Arnold, for developing a method known as phage display and using it for the directed evolution of antibodies, with the aim of producing new pharmaceuticals. ... Today, monoclonal antibodies account for a third of all new treatments.

21 Jun 2018: Understanding the activation mechanism of the serotonin receptor and the mode of binding of a failed anti-migraine drug, donitripan, will hopefully aid the development of new and improved drugs. ... Comparing the new G. o. -receptor structure to other

30 Aug 2018: These new structures show how tau folds in disease-specific ways, providing evidence for the hypothesis that different molecular structures of filamentous tau give rise to the diversity of symptoms between ... Comparison of the new structures of

16 May 2018: He then engineered the best version to be able to copy pieces of itself, and assemble them together into new full synthetic copies. ... This new synthetic biology of triplet based RNA replication might also have biotechnological applications, such as

22 Nov 2018: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures

19 Apr 2018: New work from Leo James’ group in the LMB’s PNAC Division has now revealed how TRIM21 is regulated so that it is only switched on at the right time. ... In addition, Leo’s lab has recently developed a new technique, ‘TrimAway’, which uses

4 Jan 2018: This new research has several implications for human health. It provides a simple explanation for how alcohol, which is a source of acetaldehyde, causes genetic damage and therefore acts as a ... In addition, the new insight into the function of p53 in

23 Mar 2018: Briefly mentioned Coot's new N-linked carbohydrate builder. Note: we are using latest CCP4 expert version. ... But new users will be confused. AP: PE to investigate making some videos.

7 Jun 2018: The molecular details elucidated by this new research may open avenues to develop drugs to fight infections and to design complementary therapeutic strategies for some types of cancers.

29 Mar 2018: This work opens new avenues for attempting to manipulate transport in a therapeutic setting.

5 Sep 2018: In order to make new proteins, genes are first transcribed to produce messenger RNA (mRNA) molecules, that are then translated into proteins. ... This means that this new role for tRNAs in the control of gene expression could have a role in human disease.

17 Oct 2018: In 2002, Gero established the principles of optogenetic control and thereby defined a new, now widely used, approach for probing the function of the nervous system. ... Gero studied medicine at the University of Innsbruck in his native Austria and did

19 Apr 2018: Jacques Dubochet will give the 2018 John Kendrew Lecture on Thursday 26th April at 4.00pm in the LMB’s Max Perutz Lecture Theatre.  The title of the

5 Jan 2018: Xiaowei Zhuang will give the 2017 John Kendrew Lecture on Monday 15th January 2018 at 4.00pm in the LMB’s Max Perutz Lecture Theatre. The title of the

31 Aug 2018: Wanda Kukulski, group leader in the LMB’s Cell Biology Division, has been awarded the Royal Microscopical Society’s Alan Agar Medal for Electron

17 Oct 2018: After being involved in the discovery of phospho-ubiquitin and its new conformational switch, Christina deciphered the molecular mechanism of parkin activation by phospho-ubiquitin, that parkin phosphorylation is important and

10 May 2018: Bill Schafer, group leader in the LMB’s Neurobiology Division, has been elected into the Fellowship of the Academy of Medical Sciences. The Academy

23 Mar 2018: Theo, one of the students who participated in the Challenge Project, said the project “opened up new career ideas and broadened my horizons”.

26 Jul 2018: New method identifies a selective inhibitor of PPP1R15B, a potential target for Huntington’s disease. ... This novel approach may pave the way to a new therapeutic strategy for such diseases.

28 Mar 2018: New for the 2018 Guildhall event, members of the public could pop into the special science booth to chat to the scientists about their research. ... His talk looked at the exciting work in the field of structural biology, tracing the beginnings of the

2 Aug 2018: The new study proposes that stars which give off sufficient ultraviolet (UV) light could kick-start life on their orbiting planets in the same way it likely developed on Earth, where ... This new work is the result of an ongoing collaboration between

31 May 2018: Scientists in Leo James’ group in the LMB’s PNAC Division, in collaboration with Till Böcking’s group at the University of New South Wales, Australia and Adolfo Saiardi’s group ... 6 . match the six positively charged residues in the pore. By

7 Jun 2018: disease. Led by David Komander’s group in the LMB’s PNAC Division, in collaboration with the LMB’s Biological Mass Spectrometry facility, this new work reveals insights into previously unstudied ... Christina’s work also identified a new class of

12 Jul 2018: Kiyoshi Nagai’s group in the LMB’s Structural Studies Division have used electron cryo-microscopy to solve the structure of the prespliceosome at near-atomic resolution, providing new insights into ... New work from Kiyoshi’s group has now used

11 Jun 2018: LIFE LAB events are for everyone – we hope to meet and connect with many new people.”.

24 Aug 2018: New research from Bill Schafer’s group in the LMB’s Neurobiology Division has identified how sensitisation occurs to control various behavioural states in C.

3 Aug 2018: New research from Katja Röper’s group in the LMB’s Cell Biology Division, in collaboration with Guy Blanchard at the Department of Physiology, Development and Neuroscience at the University of ... In the rest of the tissue, cells were tilted towards

18 Sep 2018: This new model of the complex allows for a greater understanding of the ways in which the components interact with each other and also demonstrated how retromer might interact with other ... This new structure and the new understanding of the role of

6 Jun 2018: This year’s Cambridge Soapbox Science took on a new dimension with scientists partnered with artists with the aim of bringing difficult science concepts to the public in exciting, innovative and ... It was amazing to then see my research incorporated

12 Jun 2018: Suffrage Science award-holders, old and new. Primary Sidebar. Search. Search this website.

9 Jul 2018: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.