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5 Sep 2014: Search this website. New mechanism of antiviral immunity discovered. New mechanism of antiviral immunity discovered. ... Published on. 5 September, 2014. Research from the LMB’s PNAC Division has revealed a new mechanism that cells use to fight

9 Dec 2014: However Sean Munro and his group in the LMB’s Cell Biology Division have now identified a whole raft of new Rab effector proteins, including several linked to human disease. ... The researchers identified numerous new Rab binding proteins that are

30 May 2014: Search this website. Novel lipid kinase structure lays the foundation for a new class of drugs. ... Novel lipid kinase structure lays the foundation for a new class of drugs.

17 Apr 2014: Search this website. New technique identifies protein production in specific cells at specific times. ... New technique identifies protein production in specific cells at specific times.

23 Apr 2014: Outside the world of science my interests are stamp collection, travelling, and learning new skills; the latest being Spanish.

12 Dec 2014: These specimen movies allowed Chris and Lori to determine some of the physical origins of this movement and design a new type of grid to reduce it. ... The new grid, made entirely of gold, reduces specimen movement about fifty times relative to the

17 Nov 2014: Specific loss of Bmal1 (green cells) in histaminergic cells (red cells) within the TMN (Images from Prof Bill Wisden lab)It is well known that all animals

14 Jan 2014: MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

14 Jan 2014: Holliger lab. MRC Laboratory of Molecular Biology. Francis Crick Avenue. Cambridge Biomedical Campus. Cambridge CB2 0QH. UK. MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

9 Jun 2014: To further demonstrate the importance of microtubules, Katja and her collaborators genetically introduced a new protein to the cells, which severs microtubules.

23 Apr 2014: Latest news. •Felix Randow was interviewed by Science Signaling on anti-bacterial autophagy.

1 Jul 2014: Published on. 1 July, 2014. A cross divisional collaboration at the LMB between the groups of Simon Bullock, in Cell Biology, and Andrew Carter, in Structural Studies, has provided new insight ... This work was funded by the MRC, a Wellcome Trust New

23 Apr 2014: I like exploring new places around the world, watching a good movie or reading an enjoyable book and relaxing through sport, especially football and skiing.

12 Jun 2014: The new research helps explain how secreted proteins, such as hormones, can cross an otherwise impermeable membrane to exit the cell. ... Since nearly all protein hormones and their receptors rely on the ribosome-Sec61 complex for their production, the

6 Oct 2014: ccp4i interface should work for most of the cases. However som new features may not be available from standard ccp4i. ... Features. It has all features of 5.7 and some new ones.

10 Nov 2014: New research by Mie Wong from Sean Munro’s group in the LMB’s Cell Biology Division has shown that when specific vesicles arrive at their correct site, they are captured

2 Dec 2014: A better understanding of how dynein works might lead to new ideas for the treatment of these diseases.

28 Nov 2014: His lab has also begun new studies on the genetic control of moulting and neurotransmitter tranport. ... This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a

1 Dec 2014: Life on Earth depends on catalysis. Chemical transformations essential for cellular function are too sluggish to happen spontaneously at ambient

23 Dec 2014: It is possible that blocking FtsZ or FtsA action in cell division might create new antibiotic targets.

3 Jul 2014: However, recent huge advances in cryo-EM, in particular the combination of new detectors (developed at MRC-LMB and elsewhere), together with Sjors new image processing program RELION, have made it

18 Mar 2014: Michael Levitt will give the Kendrew Lecture 2014 on Tuesday 25th March at 16.15pm in the LMB’s Max Perutz Lecture Theatre. The title of the lecture is

13 Jan 2014: Work carried out by Lori Passmore’s group in the LMB’s Structural Studies Division, in collaboration with Patrick Cramer’s group in Munich, has revealed

4 Aug 2014: Research carried out by Anne Bertolotti’s group in the LMB’s Neurobiology Division has identified a novel protein, named Adc17, that acts as an inducible

23 Jun 2014: Professor Peter Walter will give the 2014 Milstein Lecture on Monday 30 June 2014 at 4.15pm in the LMB’s Max Perutz Lecture Theatre. The lecture, entitled

23 Apr 2014: More recently we identified a ubiquitin-independent function of NDP52. In this new pathway NDP52 binds to Galectin 8, a cytosolic lectin that detects host glycans on vesicles damaged by Salmonella

3 Sep 2014: The prestigious Lister Institute Research Prize is awarded annually to three or four young researchers in the UK to support and nurture quality research

16 Sep 2014: This new research suggests that DNA is packaged differently after it has been damaged and that using H3.3 in this way may help cells flag regions of the genome harbouring

26 Aug 2014: Published on. 26 August, 2014. New research from Madan Babu’s group in the LMB’s Structural Studies Division, in collaboration with Toby Gibson from the European Molecular Biology Laboratory in ... However in some cases, the mRNA molecules that code

6 Aug 2014: R.Nicholls. Map sharpeining. It is more like new feature than a bug.

15 May 2014: The MRC Laboratory of Molecular Biology and AstraZeneca are today announcing a plan for a research fund to facilitate collaboration between LMB and

4 Apr 2014: Stanley received the Nobel Prize for Physiology or Medicine in 1997, “for his discovery of Prions – a new biological principle of infection”.

6 Jun 2014: Eeson developed a new method of purifying the complex from chicken cells by fusing a tag to one of the FA proteins and using this to ‘fish’ out the entire complex.

12 Sep 2014: Stephen J. Elledge, Gregor Mendel Professor of Genetics, Department of Genetics, Harvard Medical School will give the 2014 Francis Crick Lecture on Friday

22 Apr 2014: Chris and Lori made large sheets of graphene using a new custom-made instrument, designed and built here at the LMB. ... They then invented a new way to change the properties of graphene using a hydrogen plasma so they could control how proteins stick to

27 Mar 2014: On Saturday 15 and Sunday 16 March over 50 LMB scientists helped to showcase LMB research during the Cambridge Science Festival. The LMB had three

28 Mar 2014: new proteins into the EM maps and optimise their fit.

15 Apr 2014: Published on. 15 April, 2014. Harish Chandra Soundararajan and Simon Bullock from the LMB’s Cell Biology Division have created a new technique for studying how dynein motors move individual mRNA ... In the current study, unprecedented details of this

2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to

14 Apr 2014: Firstly, follow these steps:. Start a new session - close PyMOL, then re-open it. ... Start a new ProSMART CCP4i job, and load 1ryx.pdb and 1ryx_prosmart_refine.pdb as the target and reference structures, respectively.

26 Aug 2014: organisms. GOPAL, which stands for Genetically encoded Orthogonal Protection and Activated Ligation, is a new technology that allows cells to produce proteins that can be linked together in a precise way. ... The technology will help produce new protein

22 Aug 2014: The fact that the mother can protect the genomic integrity of the developing fetus is a new and significant finding.

14 Apr 2014: Firstly, follow these steps:. Start a new session - close CCP4mg, then re-open it. ... Firstly follow these steps:. Start a new session - close CCP4mg, then re-open it.

14 Apr 2014: For our next round of refinement:. Open a new REFMAC5 job in the CCP4i GUI. ... Provide the original 1ryx.mtz structure factor file in the "MTZ in" fields, and provide the new modified model in the "PDB in" field.

2 Oct 2014: A new set of conditions can easily be achieved by an increase in the salt or PEG concentration, a shift towards one of the two mixed PEGs or even a change ... Anomalous scattering centres The coupling of new crystallization screens with modern methods to

9 Jul 2014: Second option, two candidates. 12. Building the new Dictionary Clustering the data from COD. ... 15. Generator of molecule geometries using the new Dictionary. A “greedy” global optimization scheme.

6 Oct 2014: 2) Put zero inside the sphere centred at current atom with new radius. ... n4 - weighting options. New instructions (a little bit more flexible and useful for complex molecules):.

8 Nov 2014: that benefit from bacteria. Validation of. this promising new cell culture model for. ... The power of quantitative proteomics may. well shift how new biological pathways are.

30 Apr 2014: Amino acids to make new proteins and neurotransmitters. Vitamins to carry out essential processes, especially B vitamins, and to act as antioxidants (E & C).

21 Mar 2014: 2. Prepare new Matrigel plates as above or warm pre-prepared Matrigel coated dishes in the incubator. ... Add additional media needed. c. Generally minimize pipetting! 8. Transfer 0.5 ml cells per new well and place back in the incubator, being careful