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30 Apr 2013: Search this website. New mechanism in the body’s timekeeping revealed. New mechanism in the body’s timekeeping revealed. ... This provided a completely new perspective on how the circadian clock of the brain keeps accurate 24-hour time.

26 Apr 2013: Bayesian Statistics has two components: likelihood, through which new information from the experimental data is transferred to the model; and a probability distribution that ensures the model's consistency with the

1 Feb 2013: The discovery also provides useful insights into how new proteins are created in the evolutionary process. ... This represents an elegant molecular mechanism that could mediate incremental evolution of new cellular functions.

28 Oct 2013: Michael Neuberger, Deputy Director of the LMB and Head of Division of Protein and Nucleic Acid Chemistry died on Saturday 26 October, after several months

20 Dec 2013: Research from Greg Jefferis’s group in the LMB’s Neurobiology Division has uncovered a biological switch that determines which part of the fruit fly’s

9 Oct 2013: The LMB is delighted to congratulate Michael Levitt, Arieh Warshel and Martin Karplus on being awarded the 2013 Nobel Prize in Chemistry, for the

24 Jan 2013: Research in the group of Kiyoshi Nagai in the LMB’s Structural Studies Division has for the first time provided detailed information on the structure and

4 Nov 2013: 4 November, 2013. New research from Philipp Holliger’s group in the LMB’s PNAC Division demonstrates the power RNA could have wielded to enable the first forms of life on ... At its most basic level, all life can be viewed as a mechanism for

11 Jun 2013: In the second paper, published in the journal Cell, work led by Kirstin Keusekotten and Paul Elliott, in collaboration with researchers from Cologne, Munich and Copenhagen, identified a new deubiquitinating enzyme ... Identification of a new regulator

22 Oct 2013: For all of these patients, the use of PI3K delta inhibitors offers a potential and exciting new avenue of treatment aimed at normalising the function of immune cells and thereby prevent

21 May 2013: Work in Leon Lagnado’s group in the LMB’s Neurobiology Division is showing how synapses transmit visual signals in the retina of zebrafish. The group

22 Mar 2013: 22 March, 2013. The LMB is presenting a wide range of public engagement events and activities throughout 2013 to celebrate the move to its new building and the MRC Centenary.

31 Jan 2013: More generally, the study suggests that TMCs comprise a new family of ion channels that may participate in a range of sensory transduction processes in humans and other animals.

26 Jul 2013: It is with great sadness that we report that Hugh Huxley died yesterday following a major heart attack on Monday at his home with Frances in Woods Hole.

4 Mar 2013: New research, led by Leo James and Will McEwan from the LMB’s PNAC Division, has uncovered a previously unrecognised mechanism of intracellular pathogen detection which may provide a deeper understanding ... The new findings, published in Nature

11 Jul 2013: 11 July, 2013. New research from Leon Lagnado’s group in the LMB’s Neurobiology Division shows how food-related smells ‘re-tune’ zebrafish vision by making the retina more sensitive

14 Aug 2013: >New features. Note: New features are listed in reverse chronoligical order not in order of their importance. ... Version. Feature id. Feature description. Requested by. 5.8.0023. Scaling. New function for scaling has been added (by default this function

1 Jul 2013: It is better JLigand to generate new entries and links. It is an external resource at the moment. ... There are number of very good resources to generate new entries.

1 Jul 2013: In new pdb edition it their names are H5' and H5''. ... This version is compliant with new pdb. Many users. 5.41. EPE.

23 Apr 2013: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures

29 Apr 2013: New research, from a team of scientists in the LMB’s Structural Studies Division and the Texas A&M Health Science Center, illustrates the molecular mechanism behind a fundamental cellular process. ... The research, published in PNAS, provides new

14 Feb 2013: Recent advances in GPCR biology have led to the determination of new structures of several GPCRs in quick succession and this work reveals new, and critically important details about the similarities

27 Sep 2013: The molecular mechanism behind this tidal clock is still a mystery but the finding offers scope for new discoveries of how genes control biologically critical behaviour.

20 Sep 2013: Professor Scott Emr will give the 2013 Milstein Lecture on Thursday 26 September at 4.15pm in the LMB’s Max Perutz Lecture Theatre. The lecture, entitled

15 Nov 2013: Nick’s group have shown that the new ‘ligand trap’ is active in cell culture model systems and are currently testing it in a range of other models. ... The molecule identified in this work is a potentially important therapeutic which could lead to

25 Oct 2013: Joan Steitz will give the John Kendrew Lecture 2013 on Friday 1st November at 4.15pm in the LMB’s Max Perutz Lecture Theatre. The title of the lecture is

6 Feb 2013: Two factors were crucial to this success. Firstly, they recorded images with much less noise on a new type of direct-electron detector, which was co-developed with the LMB. ... Secondly, because these new cameras are also very fast, they allowed the

12 Jul 2013:

22 Jul 2013: Published on. 22 July, 2013. Work carried out by Melina Schuh’s group in the LMB’s Cell Biology Division has provided new insights into how the spindle is asymmetrically positioned

27 Jun 2013: Describe the different shapes of viruses and the process viruses use to infect a host cell, replicate, and infect new viruses. ... Ã Understanding how TRIM21 and antibodies work may help scientists devise new therapies for virus infection.

31 May 2013: Work published in the journal Structure by Kiyoshi Nagai’s group in the LMB’s Structural Studies Division, has provided further detailed information on

15 Jul 2013: While fully sequenced genomes are available for many important experimental organisms, a major challenge has been to identify the functions of the genes

28 Jun 2013: public, on Saturday 22 June, to celebrate the opening of its new building and the centenary of the Medical Research Council (MRC). ... Steve joked, to the audience’s delight, about why the new building wouldn’t work and how the LMB could up its Nobel

23 Dec 2013: The G109K substitution has a dramatic ef-fect, because in the new crystals the protein filaments are absent,but dimers are still present (Fig. ... Construction of Plasmids for Protein Purification. pMal-C2X (New EnglandBiolabs) was used to clone and

14 May 2013: structure determination and explains why the development of more. efficient crystallization screens is still challenging (McPherson &. Cudney, 2006). We are constantly testing new conditions and will. eventually integrate them into our

2 May 2013: Amazing? New? First pacemakers were introduced in the early 1960s. 3 million people worldwide use them. ... rTMS (repetitve transcranial magnetic stimulation) devices are marketed for the treatment of certain types of major depression in Canada, Australia

23 Dec 2013: CONTENT ALERTS. more>>article), Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this.

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.

30 Jul 2013: Nicotinic acetylcholinereceptorandthestructuralbasisofneuromuscular transmission:insightsfromTorpedopostsynapticmembranes. Nigel UnwinMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Abstract. The nicotinic

19 Mar 2013: C.,and De Camilli, P. (1997) The SH3 domain of amphiphysin binds theproline-rich domain of dynamin at a single site that defines a new SH3binding consensus sequence.

28 May 2013: Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. ParrotSummary:A new classical density modification program,. employing the latest techniques. ... Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. Nautilus: A new tool for nucleic acid model building Automated (CCP4i)

21 May 2013: coordinates xyz indicates where the function wants new atoms added. • Substructure completion is done by adding new atoms at these locations and then re-refining. • ... New atoms. Peaks in llg map. Calculating Electron Density • ML function is good

10 Jan 2013: information coming from the native data. This new set of phases.

5 Aug 2013: Deubiquitinases Sharpen SubstrateDiscrimination during MembraneProtein Degradation from the ERZai-Rong Zhang,1,3, Juan S. Bonifacino,1 and Ramanujan S. Hegde2,1Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child

25 Sep 2013: Email alerting service hereright-hand corner of the article or click Receive free email alerts when new articles cite this article - sign up in the box at the top.

28 May 2013: Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. ParrotSummary:A new classical density modification program,. employing the latest techniques. ... Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012. Nautilus: A new tool for nucleic acid model building Automated (CCP4i)

21 May 2013: coordinates xyz indicates where the function wants new atoms added. • Substructure completion is done by adding new atoms at these locations and then re-refining. • ... New atoms. Peaks in llg map. Calculating Electron Density • ML function is good

13 May 2013: collect data from a new, better crystal – after your return home it will not be quite as easy!Sometimes the best decision is to throw the crystal away and not waste ... if it should be discarded and a new dataset collected on a new crystal.A further

11 Jun 2013: Molecular replacement. New structures from old. The Phase Problem. amplitude. phase.