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3 Mar 2010: Search this website. Potential new target for Asthma treatment discovered. Potential new target for Asthma treatment discovered. ... It is not often that that someone identifies a new type of white cell in the blood.

25 Jun 2010: Search this website. Life through a lens: new giant lens developed at the LMB. ... We hope that researchers will be able to benefit from this new technology from next year.

14 Oct 2010: This new approach will enable researchers to improve its use as a treatment for diseases such as Parkinson’s, cerebral palsy and chronic migraine. ... This new clipping method produced a refined botox-like molecule, practical for clinical use but

21 Nov 2010: Membrane curvature and COP coated vesicle budding. ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions. Ambroggio E, Sorre B, Bassereau P, Goud B, Manneville JB, Antonny B. EMBO J. 2009, Nov19.

6 Oct 2010: The new study investigated how neurons expressing fruitless are wired up.

2 Nov 2010: The research team has further shown that increasing the amount of TRIM21 protein in cells makes this process even more effective, suggesting new ways of making better antiviral drugs. ... for developing new antiviral drugs.”.

17 Dec 2010: The key genes responsible for determining the amoebal sexes are not related to any known in other organisms, showing that a completely new mode of sex-determination has been discovered.

26 Aug 2010: into a new rhythm.”. ... If further studies in humans confirm what this study has shown in mice, this could eventually lead to an entirely new approach to treating mental illnesses such as bipolar disorder.”.

18 Oct 2010: Dr Venki Ramakrishnan’s lab from the LMB’s Structural Studies Division have uncovered the molecular mechanism by which toxins such as ricin and

7 Feb 2010: Tutorial: Validation with Coot. CCP4 Workshop New Delhi 2010. February 7, 2010.

18 Jun 2010: In support of this, overexpression or knockdown of FCHO1 and FCHO2 altered the nucleation rate of CCPs, as determined by the number of new CCPs per unit area per second. ... Together, these results reveal a new piece of the CCP assembly puzzle and

16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.].

11 Nov 2010: for some years now brought to our atten-tion the conservation of the actin andtubulin cytoskeletons across kingdomsthrough their structural studies (1, 2), arenow giving us new striking images to thinkabout ... 1). Thechange is driven by a new structural

16 May 2010: Associate the same sequence with the new Helix molecule. • Dock sidechains on the new molecule (it should work if your helix is good). • ... Coot displayes a new molecule that almost fits the so-far unbuilt density.].

15 Apr 2010: 2008. A novel component of the division-site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD.

2 Aug 2010: Further devel-opment of inhibitors guided by struc-tures could lead to a new generation of improved inhibitors with applications as chemical tools to investigate PtdIns(3)P-dependendent pathways and

1 Jun 2010: This brings the system into a new interacting ground state. c, The new ground state is characterized by identifying the state of the individual ions. ... discover novel quantum phenomena, identify new quantum phases or just design interest-ing quantum

3 Mar 2010: Tutorial: Ligand Fitting with Coot. CCP4 Workshop New Delhi 2010. March 3, 2010. ... The centre of the screen is a bit crowded now. Undisplay those new ligands.

21 Jan 2010: Coot adds intermediate white atoms and pops up a dialog]. • Accept the new atoms. ... 15. • Now optimize the fit of this new residue with Real Space Refinement.

28 Apr 2010: There are still questions about how the structure recognizes the very slight curvature of the polar membrane, but the new structural information greatly advances the discussion.

2 Aug 2010: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005. ... This can becrucial in the design of new generations of Vps34inhibitors with improved specificity, solubility,and cellular

21 Oct 2010: The identificationof quadruple as well as double filaments posed a new question,however: Which filament is present in cells? ... Both formed filaments similar to those of native TubZ. We then reconstructed the new filaments in three dimensionsto reveal

17 Feb 2010: References. Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ,Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC(2002) PHENIX: building new software for automated crystal-lographic ... Mol Microbiol 51:1321–1332. Gerdes K (2009)

14 Sep 2010: Filaments stabilized in this way continue to polymerize with the addition of new ParM subunits at both ParR–parC-capped ends, although the actual rate of elongation of an individual

20 May 2010: Corresponding authors. LW Hamoen, The Centre for Bacterial CellBiology, Medical Science New Building, Medical School, NewcastleUniversity, Richardson Road, Newcastle upon Tyne NE2 4AX, UK.Tel.: þ44 191 208 3240; Fax: þ44 ... These were then removed

2 Aug 2010: We devised a new expression and purification strategy by introducing a TEV protease. ... All propeller-shaped inhibitors create a new specificity pocket not present in the apo form of the enzyme.

20 Jul 2010: Journal of Molecular Biology, doi:10.1016/j.jmb.2010.06.030

2 Aug 2010: This conformational changelifts the phenylalanine residue of the DFG motif to disruptits interaction with helix αC, thereby creating a new hydro-phobic pocket deep behind the ATP-binding site that has ... For these inhibitors, a new pocket is formed

7 Apr 2010: Processes of membrane shaping belonging to the second classinclude transient distortions of the membrane continuity and re-connections of the membrane surface in a new way.

30 Apr 2010: Stable for at least 2 years.4. T7 or SP6 polymerase (New England Biolabs). ... chromatography resin, wash extensively with bufferscontaining the desired detergent, and elute in a buffer contain-ing this new detergent.

14 Dec 2010: predicted gene products on chromosome one, we attempt to find new molecules that. ... To. this end, the worm has proven invaluable in the identification of new molecules.

1 Dec 2010: The EMBO Journal, (2010). doi:10.1038/emboj.2010.315

4 Oct 2010: Roles of Amphipathic Helices and the Bin/Amphiphysin/Rvs(BAR) Domain of Endophilin in Membrane CurvatureGenerationSReceived for publication, March 26, 2010, and in revised form, April 16, 2010 Published, JBC Papers in Press, April 23, 2010, DOI

16 Feb 2010: To maximize the severity of the phenotype (if any) caused by CtmPrP, the new.

20 Nov 2010: This zippering explains how generation of aSNARE complex brings the membranes together, but doesnot explain the mechanism of membrane fusion per se [53].New results show that SNARE assembly tends to