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  2. PPL number: | Granted: 05 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf
    18 Jun 2021: This network will be utilised to maximise the dissemination of the new knowledge gained through this project. ... 3) By generating large quantities of human cells, where appropriate, we can continue to perform new studies using the same human cells.
  3. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_nts_expires2026_redacted.pdf
    13 Sep 2021: The new insights gained could lead to new strategies for treating such disorders, including learning disabilities and Alzheimer's disease. ... Moreover, our institution's web pages provide regular updates on new developments in the 3Rs.
  4. PPL number: | Granted: 02 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_regulation_of_fat_mass_and_its_association_with_metabolic_disease_redacted.pdf
    18 Jun 2021: tolerance, providing new information on how the genes under investigation impact human metabolism and health. ... or 'negative' in the same way that a trial of a new treatment would be.
  5. PPL number: | Granted: 12 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/promoting_proliferation_in_non-regenerative_tissues_redacted.pdf
    18 Jun 2021: The work will;. 1. Provide new insights into the mechanisms required for regeneration. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.
  6. PPL number: | Granted: 24 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf
    18 Jun 2021: This project will likely result in new information and publications about the following:. ... In recent years scientists have developed a new way of growing (culturing) cells in 3 dimensions.
  7. PPL number: | Granted: 30 Jun 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_mechanisms_involved_in_genome_regulation_nts_redacted.pdf
    13 Sep 2021: This second part will provide new hypotheses and research avenues for future research projects about mitochondrial and neurodegenerative diseases. ... Data generated from this project will form the basis for new funding applications, and may eventually
  8. PPL number: | Granted: 14 Jul 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_transposable_elements_in_cichlid_fish_development_and_evolution_nts_redacted.pdf
    13 Sep 2021: Our investigations and the data generated are expected to lead to new collaborations with other researchers. ... We will incorporate new recommendations on animal welfare, as soon as possible after their publication.
  9. PPL number: | Granted: 04 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_and_treatment_of_pulmonary_vascular_diseases_redacted.pdf
    18 Jun 2021: We aim to develop new approaches to treatment that target the pathways identified from human genetic studies. ... We will disseminate new knowledge and findings by publishing our results in internationally recognised scientific journals.
  10. PPL number: | Granted: 06 Jul 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_the_immune_system_in_cardiovascular_disease_nts_expires2026_redacted.pdf
    13 Sep 2021: However, our understanding of how this happens is still limited, and this has prevented scientists from finding new effective treatments. ... Our results will therefore benefit the scientific community through the provision of important new knowledge
  11. PPL number: | Granted: 02 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf
    18 Jun 2021: We expect to test new compounds that inhibit alpha-synuclein aggregation into clumps and spreading to delay the development of pathology. ... Several collaborations are in place and will be developed to obtain new tools to further the understanding of

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