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1 - 3 of 3 search results for endogenous retrovirus |u:www-vendruscolo.ch.cam.ac.uk where 0 match all words and 3 match some words.

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  2. The Vendruscolo Laboratory

    www-vendruscolo.ch.cam.ac.uk/research.html
    28 Feb 2023: The endogenous proteins that are sequestered by the aggregates share distinct physicochemical properties: They are relatively large in size and significantly enriched in predicted unstructured regions, features that are strongly linked

  3. Extracellular protein homeostasis in neurodegenerative diseases

    www-vendruscolo.ch.cam.ac.uk/Wilson-2023-NRN.pdf
    28 Feb 2023: Overexpression of wild-type transthyre-tin in the APP23 mouse model of AD reduced cognitive and motor impairments, whereas silencing of the endogenous transthyretin gene promoted neuropathology76. ... Inspired by this mechanism, endogenous internal-izing

  4. Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience …

    www-vendruscolo.ch.cam.ac.uk/Joshi-2023-ACSCN.pdf
    2 Mar 2023: We tested human endogenous fat-soluble(red) and water-soluble (blue) vitamin metabolites in a ThT-basedscreen to identify vitamin metabolites that either accelerate or delaythe aggregation of Aβ42. ... Togetherwith the C. elegans experiments, these data

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