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Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and Results that match 1 of 2 words
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How eating feeds into the body clock - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/how-eating-feeds-into-the-body-clock/25 Apr 2019: These are endogenous daily rhythms that occur in every cell of the body; affecting a wide range of physiological processes, from when we sleep, to hormone levels, to how quickly we -
Insights into how KAP1 silences viral origin DNA in our genomes - MRC …
https://www2.mrc-lmb.cam.ac.uk/insights-into-how-kap1-silences-viral-origin-dna-in-our-genomes/10 Jul 2019: KAP1 is the primary regulator of these retrovirus insertions. Guido Stoll, a PhD student in Yorgo’s group, used X-ray crystallography to determine the structure of the part of KAP1 -
Decade-long collaboration results in the first structure of the…
https://www2.mrc-lmb.cam.ac.uk/decade-long-collaboration-results-in-the-first-structure-of-the-fanconi-anaemia-core-complex/31 Oct 2019: to exogenous chemicals, such as chemotherapeutic drugs and alcohol, or endogenous by-products of normal cellular metabolism. -
Articleshttps://doi.org/10.1038/s41594-019-0196-z A folded…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%20NSMB%202019%20SI.pdf26 Feb 2019: c, Growth of strains containing point mutations at the elbow in the endogenous mukB gene. -
The ER membrane protein complex promotes biogenesis of sterol-related …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/JCS_2019.pdf18 Jan 2019: SQS insertion by EMC enables sterol biosynthesisTo determine the mechanism responsible for downregulating SQSin EMC-knockout cells, we monitored endogenous SQS synthesisand turnover by performing 35S-Met/Cys pulse-chase assays. ... A) 35S-Met/Cys -
Articleshttps://doi.org/10.1038/s41594-019-0196-z 1MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%202019%20NSMB.pdf4 Mar 2019: Articleshttps://doi.org/10.1038/s41594-019-0196-z. 1MRC Laboratory of Molecular Biology, Cambridge, UK. 2Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK. 3Bioanalytics, Institute of Biotechnology, Technische -
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https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. Competing interest: See. page 28. Funding: See page 28. Received: 11 March 2019. Accepted: 15 May 2019. Published: 16 May 2019. Reviewing editor: Maya. Schuldiner, Weizmann Institute,. Israel. Copyright -
Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: Nature Structural & Molecular Biology, doi:10.1038/s41594-019-0331-x -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Cite as: Z. Lin et al., Science 10.1126/science.aaz4352 (2019). REPORTS. First release: 14 November 2019 www.sciencemag.org (Page numbers not final at time of first release) 1. Alpha and beta tubulins form obligate heterodimers (hereaf-ter
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