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Melina Schuh awarded the EMBO Gold Medal - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/melina-schuh-awarded-the-embo-gold-medal/
16 May 2018:
This method is the first widely applicable protein degradation method that acts directly on the level of the endogenous protein.
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The ER membrane protein complex is a transmembrane domain insertase
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf27 Jan 2018: This system contains endogenous mRNAs (primarily encoding the 14 kD globins and a prominent 70 kD protein) that contribute to background, but has the advantage of retaining native cytosolic conditions, most ... aureus is used to digest endogenous mRNA.
16 May 2018:
This method is the first widely applicable protein degradation method that acts directly on the level of the endogenous protein.
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