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Methods Passmore Lab
https://www2.mrc-lmb.cam.ac.uk/groups/passmore/Methods.html5 Jan 2024: tag endogenous genes in human cells. -
Leo James - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/h-to-m/leo-james/25 Aug 2023: A Method for the Acute and Rapid Degradation of Endogenous Proteins.. -
Scientific Glossary - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-glossary/21 Jul 2023: chemotherapeutic drugs and alcohol, or endogenous by-products of normal cellular metabolism. -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: A Method for the Acute and Rapid Degradation of Endogenous Proteins. -
Books - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/21 Jul 2023: Paperback, 135pp. Includes: Technology Transfer in Britain: The case of Monoclonal Antibodies, Self and Non-self: A history of Autoimmunity, Endogenous Opiates, The Committee on Safety of Drugs. -
Kate McDole - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/h-to-m/kate-mcdole/21 Jul 2023: Generation and live imaging of an endogenous Cdx2 reporter mouse line.. -
LMB Fellows - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/lmb-fellows/23 Apr 2024: His application of forward-genetic screens discovered the Human Silencing Hub ‘HUSH’, the critical transcriptional epigenetic repressor complex for silencing both newly integrated retroviruses and mobile endogenous retrotransposons. -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: This yielded protein levels of CreS similar to endogenous levels in wt strain CB15N (SI Appendix, Fig. ... Subcellular Organization of CreS Filaments. The ultrastructure of endogenous CreS assemblies at normal levels in C. -
The patterned assembly and stepwise Vps4-mediated disassembly of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hurtig%202023%20sciadv.ade5224.pdf16 Jul 2023: 1A), hereafter calledVps4E209Q. This point mutation prevents AAA-ATPases like Vps4from hydrolyzing bound ATP and can therefore interfere with theactivity of endogenous Vps4 complexes when overexpressed (24,28). -
Diverse cytomotive actins and tubulins share a polymerization switch…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Wagstaff%202023Sci%20Advances%20cytomotive%20switch%20sciadv.adf3021.pdf16 Jul 2023: Note that using this pro-cedure, only the α-tubulin is overexpressed, and this is enough torecover functional αβ-tubulin heterodimers, as the recombinantα-tubulin associates with endogenous β-tubulin. ... The absence of endogenous, untagged
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