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Group Summaries for Alumni | Department of Pharmacology
https://www.phar.cam.ac.uk/group-summaries-alumni1 May 2024: derived from the most clinically advanced AURKA inhibitor, alisertib, that are able to clear both endogenous and exogenous AURKA from cells and to downregulate its interphase functions. -
Feed aggregator | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator1 May 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the -
Funded PhD Opportunities | Department of Pharmacology
https://www.phar.cam.ac.uk/postgraduate/studentships1 May 2024: It should also be possible to explore the effects of endogenous modulators to some degree by altering the concentrations of Ca2+, Mg2and ATP in the pipette solution. -
Congratulations to Abigail Pearce for her successful PhD viva! |…
https://www.phar.cam.ac.uk/news/congratulations-abigail-pearce-her-successful-phd-viva1 May 2024: Viva. Her thesis she defended is entitled "Influence of Peptide Allosteric Modulators on Agonist Bias at Class B1 G protein-Coupled Receptors", which looks at the endogenous mechanisms by which Class -
Previous Seminar Series Talks | Department of Pharmacology
https://www.phar.cam.ac.uk/previous-seminar-series-talks1 May 2024: 17th Febuary. Dr Shafaq Sikander. William Harvey Research Institute. Endogenous and immunological mechanisms of musculoskeletal pain. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/rahman/pub1 May 2024: 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. -
Projects available for October 2024 | Department of Pharmacology
https://www.phar.cam.ac.uk/postgraduate/abstracts1 May 2024: Indicating we can reprogram an organ with extremely limited endogenous regenerative potential towards cardiomyogenesis. -
Phar Cambridge RSS Paper feed | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator/sources/221 May 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/taylor/Pub1 May 2024: Mol. Pharm. 92, 533-545. Keebler, MV & Taylor CW (2017) Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites. ... 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. Biochem. J. -
Recent Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator/sources/121 May 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the
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